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There is an unmet need to develop new agents or strategies against therapy resistant pancreatic cancer (PanCA). Recent studies from our laboratory showed that STAT3 negatively regulates NF‐κB and that inhibition of this crosstalk using Nexrutine® (Nx) reduces transcriptional activity of COX‐2. Inhibition of these molecular interactions impedes pancreatic cancer cell growth as well as reduces fibrosis...
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