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The nanocrystalline fraction of the natural biopolymer bacterial nanocellulose (BNC) was isolated by controlled degradation resulting in anionic surface modifications. The potential of those nanowhiskers for safe and efficient gene delivery was tested using electrostatic layer assemblies with different poly(ethylene imine)s (2.5 and 25 kDa) and plasmid DNA. For different isolation techniques (sulfuric...
For the loading of the natural biopolymer bacterial nanocellulose (BNC) with drugs, usually an adsorption method has been described. In the present study, a high-speed loading technique based on vortexing was established for the incorporation of proteins in BNC as drug delivery system. Compared to the conventional technique, vortexing accomplished in 10min the same protein loading capacity as the...
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