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Introduction
The effect of whole‐grain (WG) versus refined‐grain (RG) diets on glucose‐stimulated insulin secretion (GSIS) and β‐cell function is unclear.
Methods
In a double‐blind crossover randomized controlled trial, 13 prediabetic adults (37.2 ± 1.8 y, BMI: 33.6 ± 1.4 kg m−2, 2 h glucose: 146.9 ± 11.6 mg dL−1) are provided isocaloric‐matched WG and RG diets for 8‐weeks each, with an 8–10 week...
Whole-grain intake is associated with lower risk of type 2 diabetes but the mechanisms are unclear.We tested the hypothesis that a WG diet reduces insulin resistance and improves glucose use in individuals at risk for type 2 diabetes compared with an isocaloric-matched refined-grain diet.A double-blind, randomized, controlled, crossover trial of 14 moderately obese adults (Age, 38 ± 2 y; BMI, 34.0 ± 1...
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