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A label-free electrochemical aptasensor was developed for selective detection of saxitoxin (STX). It is taking advantage of target-induced conformational change of an STX-specific aptamer when it binds to the toxin. A monolayer of octadecanethiol was deposited on a gold electrode, and then coated with a film of multiwalled carbon nanotubes (MWCNTs) to which the aptamer was covalently conjugated. Methylene...
A new electrochemical sensing platform was designed for sensitive detection of copper(II) (Cu2+) based on click conjugation of two short oligonucleotides by using methylene blue‐functionalized hairpin DNA as the template. The analyte (Cu2+) was in situ reduced to Cu+ by sodium ascorbate, which catalyzed the click conjugation between two single‐stranded oligonucleotides one was labelled with a 5′‐alkyne...
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