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In this paper, a novel hybrid multi-objective optimization algorithm based on the nondominated sorting genetic algorithm II for large array thinning is presented. The iterative fast Fourier transform (IFFT) technique with a judge factor is introduced into the optimizer to accelerate the convergence. The global characteristics of a genetic algorithm show its optimization capability in the early phase...
Due to the existence of systematic bias in the measurements, inter-chip normalization is required before integrated data analysis of multiple microarray datasets. Current inter-chip normalization methods rely on some assumptions, which can rarely be verified by experiments, such as the invariant expression level of housekeeping genes or the stability of statistical data distribution. In this paper,...
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