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Purpose Copper peptide (GHK-Cu) plays an important role in skin regeneration and wound healing. However, its skin absorption remains challenging due to its hydrophilicity. Here we use polymeric microneedle array to pre-treat skin to enhance GHK-Cu skin penetration. Methods Two in vitro skin models were used to assess the capability of microneedles in facilitating skin delivery of GHK-Cu. Histological...
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