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The Cre‐loxP system has been widely used for specific DNA recombination which induces gene inactivation or expression. Recently, photoactivatable‐Cre (PA‐Cre) proteins have been developed as a tool for spatiotemporal control of the enzymatic activity of Cre recombinase. Here, we generated transgenic mice bearing a PA‐Cre gene and systematically investigated the conditions of photoactivation for the...
Cover illustration: The cover image is based on the Research Article Repetitive short‐pulsed illumination efficiently activates photoactivatable‐Cre as continuous illumination in embryonic stem cells and pre‐implantation embryos of transgenic mouse by Kanae Kishi et al., https://doi.org/10.1002/dvg.23457.
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