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The limits of supercritical fluid chromatography have been experimentally explored using inlet pressures at the limits of the current commercial instrumentation (400–600 bar), as well as pressures significantly surpassing this (up to 1050 bar). It was found that efficiencies in the range of 200,000 theoretical plates can be achieved for a void time t0 of roughly 6min using superficially porous particles...
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