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Exosomes are small (30–100 nm) membrane vesicles that serve as regulatory agents for intercellular communication in cancers. Currently, exosomes are detected by immuno‐based assays with appropriate pretreatments like ultracentrifugation and are time consuming (>12 h). We present a novel pretreatment‐free fluorescence‐based sensing platform for intact exosomes, wherein exchangeable antibodies and...
Ein Fluoreszenzsensor für intakte Exosome, der keine Probenvorbehandlung voraussetzt, wurde durch molekulares Prägen und anschließende Modifizierung hergestellt. In ihrer Zuschrift auf S. 1626 ff. zeigen T. Takeuchi et al., dass durch Anbringen von Antikörpern und molekularen Fluoreszenzreportern ausschließlich in den nanoskopischen Bindebuchten ein hoch empfindlicher Exosomen‐Nachweis gelingen kann...
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