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Terapia genowa jest jedną z najbardziej dynamicznie rozwijających się w ostatnich latach dziedzin medycyny. Toczą się liczne próby efektywności tej terapii m. in. w chorobach dziedzicznych (muskowiscydoza, rodzina hipercholesterolemia), niektórych typach nowotworów (czerniak złośliwy, raki płuc, piersi, jajnika), czy zaburzeń w układzie krążenia (zjawisko restenozy po zabiegu PTACA) (1,2). Podstawą...
Brainstem serotonin (5-HT)-containing cells are remarkable for their widespread axonal projections and having their highest activity during wakefulness and lowest during rapid eye movement sleep. One important site of action of 5-HT is on upper airway motoneurons. However, which of the 14 known 5-HT receptors mediate the effects is uncertain. We used the reverse transcriptase/polymerase chain reaction...
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