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This paper describes the application of adaptive neuro-fuzzy inference architecture for supporting the diagnosis of lumbar disc herniation. The fuzzy system has been trained with the backpropagation gradient descent method in combination with the least squares method. A total of 38 patients have been divided into training and testing data sets. The performance of the fuzzy model has been evaluated...
Eimeria is an internal animal parasite that causes serious diseases and animal death, and reduces animal productivities. Eimeria has more than one species for every single genus of animals. An early diagnosis of Eimeria infection is usually achieved by examining fecal microscopy images. As Eimeria oocysts vary in terms of shapes, sizes and textures, they can be detected by measuring differences in...
The reasons for hearing loss are complex and currently the mechanics are not entirely clear. Outer hair cell (OHC) loss is believed to play an important role. Experimental observations shown that damage on OHCs due to ototoxic acid starts from the outermost row to the innermost row, whereas, loss of OHCs due to intense noise exposure occurs from the innermost row to the outermost row. Inspired by...
Science and technology are ever more frequently used in sports for achieving the competitive advantage. Motion tracking systems, in connection to the biomechanical biofeedback, help in accelerating motor learning. Requirements about various parameters important in real-time biofeedback applications are discussed. Special focus is given on feedback loop delays and its real-time operation. Optical tracking...
This paper aims to highlight importance of coupled thermo-mechanical analysis of structures and devices made of shape memory alloys (SMA). Ti-Ni alloys are recognized as very biocompatible SMA, so theirs usage is very often in medical purpose. Stent implants made of SMA are the best known application of such materials, so the unit cell of some typical stent model is used to demonstrate the necessity...
The reported study represents a nice example of how state-of-the-art molecular modeling techniques can be used to study complicated macromolecular complexes, whose structures have not yet been experimentally determined, and to validate these against the available experimental data. The proposed structure will facilitate future studies on the rational design of successful Aflatoxin B1 (AFB1) modulators...
The finite element method is increasingly used in the analysis of blood flow through blood vessels. Our work represents the research of blood flow through a cerebral aneurysm. The current work describes the blood flow in 4 patient-specific models of saccular aneurysms. They are located in the region of the anterior and posterior circulation of the circle of Willis. The unstructed grids are constructed...
With limited researches, there is still lack of pathway networks of Chuan-wu (also called Aconitum carmichaelii) against rheumatoid arthritis which might provide clues for further researches. In this study, started from the chemical compounds, proteins targeted by Chuan-wu were explored. After that, pathway networks enriched with these targeted proteins were analyzed with hypergeometric distribution...
Atherosclerosis is a medical condition becoming the number one cause of death worldwide. For this reason, any developement that may help physicians in early diagnostic and selection of the most appropriate treatment strategy is of great importance. In this paper we describe three-dimensional computer model of plaque formation and development for human coronary artery. In order to validate proposed...
Gait analysis is nowadays considered, as a promising contributor towards early detection of cognitive and physical status deterioration when it comes to elderly people. However, the majority of recent efforts on indoor gait analysis methodologies are limited as they only exploit the average walking speed. Applying density based clustering algorithms on indoor location datasets could accelerate context...
Free radical scavenging of gallic acid was studied through electron transfer mechanism (ET) in water and pentylethanoate solutions. Examination was performed using density functional theory (DFT) and Marcus theory. Three particular free radicals were selected for analysis of mechanistic pathway of the second step of sequential proton loss electron transfer (SPLET). Based on the thermochemical and...
Mandible internal fractures are a common injury because of the mandible's lack of structural support. For the treatment of such injuries various fixation elements are used. In order to improve quality of the orthodontists interventions anatomically correct and geometrically accurate customized implants are necessary. In this paper an example of accurate geometrical model of the customized plate implant...
Image filtering is one of the most common and important tasks in image processing applications. In this paper, image processing using a mean filtering algorithm combined with thresholding and binarization algorithms for the 3D visualization and analysis of murine lungs is explained. These algorithms are then mapped on the Maxler's MAX2336B Dataflow Engine (DFE) to significantly increase calculation...
In the past, genome sequence databases had used main memory indexing, such as the suffix tree, for fast sequence searches. With next generation sequencing technologies, the amount of sequence data being generated is huge and main memory indexing is limited by the amount of memory available. K-mer based techniques are being more used for various genome sequence database applications such as local alignment...
We present ePGA (electronic Pharmacogenomics Assistant), a web-based system that offers two main services to the engaged pharmacogenomic biomedical communities namely, explore — a service to search and browse through established pharmacogenomic gene-drug associations, and translate — a service to infer metabolizing phenotypes from individual genotype profiles. Furthermore, we present our work on utilizing...
In this research, a web-based simulator is developed, which can be used for generating image sequences of moving spermatozoa cells. It can be used for assessment of multiple object tracking algorithms, especially Computer Aided Sperm Analysis (CASA) systems. The developed software has many useful parameters such as blurring images or adding noise and it also gives full control of sperm counts and...
Discovering useful patterns in medical time series data such as EEG and EMG recordings is an important step for gaining useful insights into the data and medical problem under investigation, and for building accurate classifiers. However, pattern mining algorithms often require a binning step, which maps the time series data into a representation in terms of discretized values, in order to discover...
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