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Continuous monitoring of an individual's stress levels is essential to manage stress and mental state in an effective way. With increasing ubiquity of wearable heart rate monitors and their unobtrusiveness, HRV (Heart rate variability) derived from heart rate signals has emerged as one of the most relevant parameters for continuous monitoring of stress. In the present work, we have made an attempt...
In bioindustrial large scale fermenters microorganisms are exposed to conditions of unsteady nutrient supply which occur only rarely on small lab-scale fermenters and lead to economic losses. In aerobic processes cells face different availabilities of oxygen, nitrogen and carbon sources along various directions inside a fermenter. The adaptation of the central metabolism in the facultative anaerobic...
In medical procedures, needle insertion is a challenging task highly dependent on the surgeon's manual skills. Implanted needles are used for drug delivery, biopsy, delivery of radiation sources, etc. In the named clinical procedures, the accuracy of the needle placement is crucial for patient treatment outcomes. Therefore, we have proposed an automated medical device for needle implantation to eliminate...
In this paper we present a method for brain tumor segmentation and assess its performance discussing parameters — complexity of initial conditions that need to be set manually, tumor surface area recognition, and computational time. The methodology includes performing segmentation on computerized tomography (CT) medical images from 37 patients. Furthermore, one approach to user friendly two- and three-dimensional...
In this paper the methodology of vertical jump analysis is presented. Measured results of vertical force during jump are presented. Six subjects (members of "Red star" football club) perform different types of jump (flywheel jump, jump without flywheel, and jump with landing on the left and right foot while vertical ground reaction force is measured using a force plate. One axial load cell...
The independence and the maintenance of the autonomy of the elderly promotes the self-care and the quality of living of the long-lived population. With the aid of Information and Communication Technologies (ICT), KINOPTIM project develops a tele-monitoring solution to be used by the elderly in their home environment in order to reduce the risk of falls by remotely monitoring the mobility of the persons...
In order to improve locoregional tumor control obtainable with radiation therapy (RT) alone, many approaches have been used. In the past decade, focus of interests was on metal-enhanced RT as metal nanoparticles (NP) held promise in simulation studies as well as both in vitro and in vivo radiosensitizing investigations. Gold NPs have predominantly been studied showing unequivocally great potential...
Calcium silicate cements (CSC) present numerous properties that favor its use in dentistry. The purpose of this study was to investigate how the addition of soy extract affects porosity and wettability of the CSC. Soy was added to commercially available CSC named Portland cement (Italcementi, Spa Bergamo, Italy) at 10 weight % Pure Portland cement was used as a control material. Particle cement size...
The main objective of the study was to treat Alzheimer's disease (AD) plaques using focused ultrasound (FUS) induced blood brain barrier (BBB) opening with and without delivery of antibodies in a rabbit model for AD. The animal model was achieved by feeding a high cholesterol diet to rabbits for 4 months. A single spherically focused MRI compatible transducer was used which operated at 1 MHz, had...
Optic disc is one of the fundamental regions located in the internal retina that helps ophthalmologists in analysis and early diagnosis of many retinal diseases such as optic atrophy, optic neuritis, papilledema, ischemic optic neuropathy, glaucoma and diabetic retinopathy. An accurate and early diagnosis requires an accurate optic disc examination. Presence of different retinal abnormalities and...
Drug traffickers are active and always looking for new ways to mix drugs to avoid their detection and identification. One example is black cocaine, which is a mixture of cocaine base and cocaine hydrochloride and other additional substances. It is challenging for investigators to accurately identify the test for investigative purposes without conducting an on-site evaluation. Presumptive drug test...
In this paper, we propose a computationally efficient method to estimate the optimal order of the autoregressive (AR) modeling of electroencephalographic (EEG) signals in order to use the AR coefficients as features for the analysis of EEG signals and the automatic detection of epileptic seizures. The estimation of the optimal AR-order is made using regression analysis of statistical features extracted...
In this paper, we described the practical application of data mining methods for estimation of survival rate and disease relapse for breast cancer patients. A comparative study of prominent machine learning models was carried out and according to the achieved results we concluded that the classifiers obviously learn some of the concepts of breast cancer survivability and recurrence. These algorithms...
Cochlea is a part of the inner ear and it has complex anatomy and function. The proper functioning of the cochlea includes the generation of a traveling wave along the basilar membrane, which leads to depolarization of hair cells in the Organ of Corti and subsequent auditory nerve excitation (mechanoelectrical transduction). To represent the behavior of the organ of Corti, electro-mechanical cochlea...
The bioactive and degradable 70poly(50lactic-co-50glycoric acid)/30(60SiO2-40CaO) composite, which had a dual pore structure, was synthesized by a gas expansion method. The bioactive 60SiO2-40CaO powders were prepared through a sol-gel method from tetraethyl orthosilicate and calcium nitrate tetrahydrate under nitric acidic condition followed by the heat treatment at 900oC for 1 h. The 70poly(50lactic-co-50glycoric...
Using methods of molecular modeling, we have derived a universal spatial model of the orange carotenoid protein (OCP) and phycobilisome (PBS) core interaction in process of energy excess dissipation. The protrusion of the phy-cobilin domain (PB) of the core-membrane linker polypeptide (Lcm) forms the interaction site for the OCP central cavity on the PBS core surface. This spatial arrangement has...
In this paper, we propose an acoustic signal synthesizing algorithm called two-step reconstruction algorithm based on the geometrical information of ROI(region of interest). Even though we apply the same conventional reconstruction algorithm, we can obtain the better image quality of ROI by using the proposed two-step reconstruction algorithm. We comment on the mathematical minor mistakes in applying...
An easily performed and objective test of patients fine motor skills would be valuable in the diagnosis of Parkinson's disease (PD). In this study we present a set of automatic methods for quantifying the motor symptoms of PD and show that these automatically extracted features can be used to distinguish PD from other movement disorders causing tremor, namely essential tremor (ET), functional tremor...
The importance of the development of the Primary Care network in a developed country is indisputable high. The increasing pressure for productivity improvement and reduction of costs, requires activities focusing on the control and optimization of care processes improving their efficiency and effectivity. A keystone in such priority is the utilization of several effective and comprehensive processes...
In spite of numerous studies on biomechanics of the mucous membrane supported dentures, satisfactory determination of the mucous membrane loads is still lacking. The aim of this study was to evaluate the effect of different mucosa thickness and resiliency on stress distribution of complete denture using a three-dimensional finite element analysis. A edentulous mandible with complete denture was converted...
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