To compare the effects of taping techniques on clinical measures in patellofemoral pain syndrome (PFPS) patients.Crossover experimental design.Controlled laboratory.Twenty physically active PFPS patients.Isokinetic strength and endurance, and perceived pain.Bilateral baseline differences existed for strength (involved = 1.8 ± 0.5 Nm/kg; uninvolved = 2.1 ± 0.5 Nm/kg; p = 0.001) and endurance (involved = 35.6 ± 14.0 J/kg; uninvolved = 40.2 ± 12.9 J/kg; p = 0.013). Strength (McConnell = 2.1 ± 0.6 Nm/kg, 95% SCI = (1.1, 4.2); Spider ® = 2.1 ± 0.5 Nm/kg, 95% SCI = (0.9, 4.0)) and endurance (McConnell = 42.9 ± 13.8 J/kg, 95% SCI = (2.9, 11.6); Spider ® = 42.5 ± 11.0 J/kg, 95% SCI = (2.6, −11.3)) increased when taped compared to baseline. Pain decreased during strength (baseline = 3.0 ± 2.2 cm; McConnell = 1.9 ± 1.7 cm, 95% SCI = (−1.8, −0.4); Spider ® = 1.6 ± 2.0 cm, 95% SCI = (−2.0, −0.5)) and endurance (baseline = 2.5 ± 2.0 cm; McConnell = 1.5 ± 1.8 cm, 95% SCI = (−1.6, −0.4); Spider ® = 1.1 ± 0.8 cm, 95% SCI = (−1.7, −0.5)) measurements when taped. Differences between taping techniques were insignificant.Taping improved clinical measures in PFPS patients. No differences existed between Spider ® and McConnell techniques.