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The cellular functions, such as tissue‐rebuilding ability, can be directly affected by the metabolism of cells. Moreover, the glucose metabolism is one of the most important processes of the metabolism. However, glucose cannot be efficiently converted into energy in cells under ischemia hypoxia conditions. In this study, a high‐energy intermediate fructose hydrogel (HIFH) is developed by the dynamic...
Exudate management is critical to improve chronic wound healing. Herein, inspired by a Janus‐structured lotus leaf with asymmetric wettability, a Janus electrospun short fiber scaffold is fabricated via electrospinning technologies and short fiber modeling. This scaffold is composed of hydrophilic 2D curcumin‐loaded electrospun fiber and hydrophobic 3D short fiber via layer‐by‐layer assembly and electrostatic...
Macrophage immunotherapy is an emerging treatment strategy that modulates the immune system to promote wound healing. The functionality and regeneration of tissue depend on spatially and temporally regulating the biophysical and biochemical microenvironmental with poorly understood mechanisms. Biomaterials are carefully crafted to display and deliver macrophage regulatory signals in a precise and...
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