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The preparation of structured antibody layers was shown. For this purpose, a (3‐aminopropyl)‐trimethoxysilane (APTMS) monolayer on a silicon wafer was pholithographically structured. To the APTMS structures, IgG antibodies can easily be attached via glutaraldehyde coupling. To prevent unspecific bonding to the bare silicon substrate, a commercial blocking agent has to be used.
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