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Engrailed‐1 (EN1) is a developmental gene that encodes En1, a highly conserved transcription factor involved in regionalization during early embryogenesis and in the later maintenance of normal neurons. After birth, EN1 still plays a role in the development and physiology of the body; for example, it exerts a protective effect on midbrain dopaminergic (mDA) neurons, and loss of EN1 causes mDA neurons...
We demonstrate a THz-biochip integrated with a compact high-efficiency micro-THz source with tunable THz frequencies for direct, sensitive, localized label-free bio-sensing. The capability to identity different illicit drug powders is successfully demonstrated.
Transitional cell carcinoma of the urinary bladder is associated with occupational exposure to 4,4′-methylenebis(2-chloroaniline) (MBOCA). A program to monitor MBOCA levels in the work environment and to screen for bladder cancer was performed at four MBOCA manufacturing factories. The U.S. Occupational Safety and Health Administration analytic method No. 24 was adopted in this study to measure...
General regulations and risk assessment regarding toxicants are single-compound oriented even though humans are exposed to multi-chemicals in the general environment. This study investigated the effects of different levels of N,N-dimethylformamide (DMF) and co-exposure levels of methyl ethyl ketone (MEK) and toluene (TOL) on two biomarkers of DMF exposure: non-metabolized urinary (U-)DMF and the DMF...
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