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Maciej Przybyłek

user

City

Bydgoszcz

Institution

Nicolaus Copernicus University Collegium Medicum in Bydgoszcz

Role

Academic staff

External Ids

OrcId: 0000-0002-3399-6129
PbnId: 3969096
ResearcherId: D-6353-2014

Interests

Other Engineering and Technologies, Nanotechnology, Mathematics and 15 other

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Keywords

Organic chemistry, Crystallography, Mass spectrometry, Molecular modelling, PharmacyEnvironmental chemistry, Chromatography, Physical chemistry, Photochemistry, Analytical chemistry, Spectroscopy, Theoretical chemistry, Crystal engineering

Resources

article

Thermodynamics and Intermolecular Interactions of Nicotinamide in Neat and Binary Solutions: Experimental Measurements and COSMO-RS Concentration Dependent Reactions Investigations

Piotr Cysewski, Maciej Przybyłek, Anna Kowalska, Natalia Tymorek

7365

In this study, the temperature-dependent solubility of nicotinamide (niacin) was measured in six neat solvents and five aqueous-organic binary mixtures (methanol, 1,4-dioxane, acetonitrile, DMSO and DMF). It was discovered that the selected set of organic solvents offer all sorts of solvent effects, including co-solvent, synergistic, and anti-solvent features, enabling flexible tuning of niacin solubility...
article

Solvent Screening for Solubility Enhancement of Theophylline in Neat, Binary and Ternary NADES Solvents: New Measurements and Ensemble Machine Learning

Piotr Cysewski, Tomasz Jeliński, Patryk Cymerman, Maciej Przybyłek

7347

Theophylline, a typical representative of active pharmaceutical ingredients, was selected to study the characteristics of experimental and theoretical solubility measured at 25 °C in a broad range of solvents, including neat, binary mixtures and ternary natural deep eutectics (NADES) prepared with choline chloride, polyols and water. There was a strong synergistic effect of organic solvents mixed...
article

Thermodynamic Characteristics of Phenacetin in Solid State and Saturated Solutions in Several Neat and Binary Solvents

Maciej Przybyłek, Anna Kowalska, Natalia Tymorek, Tomasz Dziaman, more

4078

The thermodynamic properties of phenacetin in solid state and in saturated conditions in neat and binary solvents were characterized based on differential scanning calorimetry and spectroscopic solubility measurements. The temperature-related heat capacity values measured for both the solid and melt states were provided and used for precise determination of the values for ideal solubility, fusion...

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Public collections

collection

Green solvents

Maciej Przybyłek
collection

Mass Spectra Interpretation

Maciej Przybyłek
collection

Organochlorine Pollutants

Maciej Przybyłek

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