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chapter

Experimental realization of a decentralized active disturbance rejection controller for a coupled tank system

Soumya Ranjan Mahapatro, Bidyadhar Subudhi, Sandip Ghosh

TENCON 2017 - 2017 IEEE Region 10 Conference > 1137 - 1141

TENCON 2017 - 2017 IEEE Region 10 Conference

This paper presents design and real-time implementation of a decentralized active disturbance rejection controller (ADRC) for liquid level regulation of a coupled tank system. To obtain a suitable feasible model of the coupled tank system, in this work system identification approach is employed. Further, based on the identified model, a decoupler has been designed to reduce the coupling effects between...

article

The limits of food safety testing: A case study of Escherichia coli testing of beef trim

Peyton Ferrier, Jean C. Buzby, P. Ferrier, J.C. Buzby

Food Control > 2014 > 38 > Complete > 227-234

Beef trim, the primary component of ground beef, is tested by both the Food Safety and Inspection Service (FSIS) and meat packers for Escherichia coli O157:H7 under a zero tolerance standard. We compare and contrast the process control and filtering roles of this testing on costs and food safety outcomes. Both of these roles of testing have been alternatively emphasized in recent legislative proposals...

article

Analysis of 2D and 3D circular braiding processes: Modeling the interaction between the process parameters and the pre-form architecture

G. Guyader, A. Gabor, P. Hamelin, G. Guyader, more

Mechanism and Machine Theory > 2013 > 69 > Complete > 90-104

This paper focuses on the modeling of a 2D and 3D circular braiding process to establish the adapted relationships between the architecture of the complex-shaped braids and the process parameters by considering the transitory and steady-state process stages. The modeling approach is based on differential geometry. We describe the trajectory of a strand of yarn as a parameterized curve on an elementary...

article

Fault detection and isolation and fault tolerant control of a catalytic alkylation of benzene process

David Chilin, Jinfeng Liu, Xianzhong Chen, Panagiotis D. Christofides

Chemical Engineering Science > 2012 > 78 > Complete > 155-166

In this work, we focus on the application of an integrated fault detection and isolation and fault tolerant control (FDIFTC) framework to a catalytic alkylation of benzene process. We consider that the catalytic alkylation of benzene process is controlled by a distributed model predictive control (DMPC) system and is subjected to unknown, persistent actuator faults. The FDIFTC system monitors closed-loop...

article

Systemes d'aide a la conduite des procedes industriels

François-Marie Lesaffre, Claude Thirion, Laurent Baudouin

Mecanique & Industrie > 2000 > 1 > 5 > 447-455

Pour la realisation de ses systemes d'aide a la conduite integrant le savoir-faire de ses meilleurs experts, USINOR a mis au point l'environnement de developpement Process Works. Il est a la fois un langage permettant de declarer les connaissances a l'oeuvre dans la conduite des procedes: modeles, perception, raisonnements, proposition d'actions, et a la fois un environnement couvrant les diverses...

article

Model‐based control of titer and glycosylation in fed‐batch mAb production: Modeling and control system development

Yu Luo, Varghese Kurian, Liqing Song, Evan A. Wells, more

AIChE Journal > 69 > 4 > n/a - n/a

Therapeutic monoclonal antibodies (mAbs) are typically manufactured using mammalian cell cultures in fed‐batch bioreactors, with increasing emphasis on meeting productivity and product quality attribute targets that depend strongly on such process variables as nutrient feed rates and bioreactor operating conditions. In this article, we identify, categorize, and address the challenges of achieving...

article

Digital twin of a continuous chromatography process for mAb purification: Design and model‐based control

Anamika Tiwari, Vishnu Swaroopji Masampally, Anshul Agarwal, Anurag S. Rathore

Biotechnology and Bioengineering > 120 > 3 > 748 - 766

Model‐based design of integrated continuous train coupled with online process analytical technology (PAT) tool can be a potent facilitator for monitoring and control of Critical Quality Attributes (CQAs) in real time. Charge variants are product related variants and are often regarded as CQAs as they may impact potency and efficacy of drug. Robust pooling decision is required for achieving uniform...

article

Development and Validation of a Calculation Routine for the Precise Determination of Pulse Overlap and Accumulated Fluence in Pulsed Laser Surface Treatment

Tobias Fox, Frank Mücklich

Advanced Engineering Materials > 25 > 3 > n/a - n/a

In laser material processing, a variety of parameters like pulse fluence, total dose, step size, and pulse‐to‐pulse overlap are used to define and compare laser processes. Of these parameters, the pulse‐to‐pulse overlap can be the hardest to access as it is not implemented directly but instead depends on the spot diameter, its shape, and the respective scanning path that is used to cover the surface...

article

Quality‐by‐control of intensified continuous filtration‐drying of active pharmaceutical ingredients

Francesco Destro, Massimiliano Barolo, Zoltan K. Nagy

AIChE Journal > 69 > 2 > n/a - n/a

Continuous manufacturing and closed‐loop quality control are emerging technologies that are pivotal for next‐generation pharmaceutical modernization. We develop a process control framework for a continuous carousel for integrated filtration‐drying of crystallization slurries. The proposed control system includes model‐based monitoring and control routines, such as state estimation and real‐time optimization,...

article

Automation of Integrated Perfusion Control Simplifying Process Intensification of Mammalian Biomanufacturing in Single‐Use Bioreactors

Markus Schulze, Dominic Kues, Wei Gao, Matthew Houser, more

Chemie Ingenieur Technik > 94 > 12 > 1968 - 1976

Production of biopharmaceuticals needs to become faster, more flexible, and efficient. Perfusion processes allow to operate cell cultivations at higher cell concentrations, shorten their process time and increase their productivity. Still, either customized software solutions or third‐party stand‐alone control devices are often used for perfusion control. Its integration into a bioreactor automation...

article

Sensor location selection for continuous pulp digesters with delayed measurements

Lu Zhang, Junyao Xie, Stevan Dubljevic

AIChE Journal > 68 > 12 > n/a - n/a

The state estimation and sensor placement for a continuous pulp digester with delayed measurements are investigated. The underlying model of interest is heat transfer in a pulp digester modeled by two coupled hyperbolic partial differential equations and an ordinary differential equation. Output measurements are considered with delay due to the possible low sampling rate. The Cayley–Tustin transformation...

article

Comparison of different extractive distillation processes for chloroform/n‐hexane separation: design and control

Xingyan Zeng, Jianting Yu, Lin Zhu, Liping Lv, more

Journal of Chemical Technology & Biotechnology > 97 > 12 > 3520 - 3533

Background When extracting total glycosides from Panax notoginseng, a waste liquid containing chloroform and n‐hexane will be produced. These waste liquids are not separated and recycled in time, which will not only waste resources but also cause environmental pollution. Chloroform and n‐hexane form an azeotrope which cannot be separated by ordinary distillation methods. This study proposes three...

article

11.3: Invited Paper: MicroLED End‐to‐End Process Control

John C. Robinson, Bobby Barnett

SID Symposium Digest of Technical Papers > 53 > S1 > 125 - 128

MicroLED displays offer many key performance benefits such as brightness, contrast, and lifetime, however, cost remains a barrier to wide market acceptance. Improved yield through better process control provides a pathway to lower costs. In this paper we discuss yield and end‐to‐end process control from epitaxy and microLED patterning, driver IC (optional), backplane, mass‐transfer, and bonding.

article

Application of a Gas Sensor Array to Effectiveness Monitoring of Air Contaminated with Toluene Vapors Absorption Process

Dominik Dobrzyniewski, Bartosz Szulczyński, Jacek Gębicki

Journal of Ecological Engineering > 2022 > Vol. 23, nr 10 > 269--282

This article demonstrates the application of a gas sensor array to monitor the effectiveness of the absorption process of air stream purification from odorous compounds (toluene vapors). A self-constructed matrix consisting of five commercially available gas sensors was used. Multiple linear regression (MLR) was selected as the statistical technique used to calibrate the matrice. Gas chromatography...

article

Model predictive control of a second‐order hyperbolic transport‐reaction process

Guilherme Ozorio Cassol, Stevan Dubljevic

AIChE Journal > 68 > 10 > n/a - n/a

The model predictive controller (MPC) design is developed for a tubular chemical reactor, considering a second‐order hyperbolic partial differential equation as the model of the transport‐reaction process with boundary actuation. Without loss of generality, closed–closed boundary conditions and relaxed total flux are assumed. At the same time, the model is discretized in time by the Cayley–Tustin...

article

Encoder–decoder neural networks for predicting future FTIR spectra – application to enzymatic protein hydrolysis

Miroslav Kuchta, Sileshi Gizachew Wubshet, Nils Kristian Afseth, Kent‐André Mardal, more

Journal of Biophotonics > 15 > 9 > n/a - n/a

In the process of converting food‐processing by‐products to value‐added ingredients, fine grained control of the raw materials, enzymes and process conditions ensures the best possible yield and economic return. However, when raw material batches lack good characterization and contain high batch variation, online or at‐line monitoring of the enzymatic reactions would be beneficial. We investigate...

article

Zastosowanie modeli ekonometrycznych w procesie cyfrowej transformacji dostaw ciepła

Małgorzata Niestępska

Ciepłownictwo, Ogrzewnictwo, Wentylacja > 2022 > T. 53, nr 7-8 > 29--36

Wizja wdrożenia kolejnego etapu zielonej transformacji w postaci negocjowanego pakietu „fit for 55” budzi obawy przedstawicieli branży energetycznej i ciepłowniczej w Polsce. Obawy te związane są przede wszystkim ze skalą wyzwań inwestycyjnych i kosztami już ponoszonymi w ramach systemu handlu uprawnieniami do emisji CO2 czyli EU ETS. Inwazja Rosji na Ukrainę zrewidowała dotychczasowe kierunki polityki...

article

A survey and comparative evaluation of actor‐critic methods in process control

Debaprasad Dutta, Simant R. Upreti

The Canadian Journal of Chemical Engineering > 100 > 9 > 2028 - 2056

Actor‐critic (AC) methods have emerged as an important class of reinforcement learning (RL) paradigm that enables model‐free control by acting on a process and learning from the consequence. To that end, these methods utilize artificial neural networks, which are synergized for action evaluation and optimal action prediction. This feature is highly desirable for process control, especially when the...

article

Economic optimization and dynamic control of pressure‐swing distillation for separating the ternary azeotrope of butanone/n‐heptane/isopropanol

Cuncheng Ma, Defeng Sun, Fangkun Zhang, Qilei Xu, more

Journal of Chemical Technology & Biotechnology > 97 > 9 > 2557 - 2571

BACKGROUND Economic optimization and dynamic control of the separation process for recovering the ternary mixture of butanone (MEK)/n‐heptane/isopropanol (IPA) from industrial wastewater is a significant topic. In this work, the optimal pressure‐swing distillation (PSD) sequence, heat integration and dynamic control for separating MEK/n‐heptane/IPA were investigated systematically. The optimal separation...

article

Process analytical technology as key‐enabler for digital twins in continuous biomanufacturing

Axel Schmidt, Heribert Helgers, Lara Julia Lohmann, Florian Vetter, more

Journal of Chemical Technology & Biotechnology > 97 > 9 > 2336 - 2346

Over the last few years rapid progress has been made in adopting well‐known process modeling techniques from chemicals to biologics manufacturing. The main challenge has been analytical methods as engineers need quantitative data for their workflow. Industrialization 4.0, Internet of Things, artificial intelligence and machine learning activities up to big data analysis have taken their share in solving...

INFONA - science communication portal

Search results

Experimental realization of a decentralized active disturbance rejection controller for a coupled tank system

The limits of food safety testing: A case study of Escherichia coli testing of beef trim

Analysis of 2D and 3D circular braiding processes: Modeling the interaction between the process parameters and the pre-form architecture

Fault detection and isolation and fault tolerant control of a catalytic alkylation of benzene process

Systemes d'aide a la conduite des procedes industriels

Model‐based control of titer and glycosylation in fed‐batch mAb production: Modeling and control system development

Digital twin of a continuous chromatography process for mAb purification: Design and model‐based control

Development and Validation of a Calculation Routine for the Precise Determination of Pulse Overlap and Accumulated Fluence in Pulsed Laser Surface Treatment

Quality‐by‐control of intensified continuous filtration‐drying of active pharmaceutical ingredients

Automation of Integrated Perfusion Control Simplifying Process Intensification of Mammalian Biomanufacturing in Single‐Use Bioreactors

Sensor location selection for continuous pulp digesters with delayed measurements

Comparison of different extractive distillation processes for chloroform/n‐hexane separation: design and control

11.3: Invited Paper: MicroLED End‐to‐End Process Control

Application of a Gas Sensor Array to Effectiveness Monitoring of Air Contaminated with Toluene Vapors Absorption Process

Model predictive control of a second‐order hyperbolic transport‐reaction process

Encoder–decoder neural networks for predicting future FTIR spectra – application to enzymatic protein hydrolysis

Zastosowanie modeli ekonometrycznych w procesie cyfrowej transformacji dostaw ciepła

A survey and comparative evaluation of actor‐critic methods in process control

Economic optimization and dynamic control of pressure‐swing distillation for separating the ternary azeotrope of butanone/n‐heptane/isopropanol

Process analytical technology as key‐enabler for digital twins in continuous biomanufacturing

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