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Items from 1 to 20 out of 1,377 results

article

Exosomal hsa_circRNA_047733 integrated with clinical features for preoperative prediction of lymph node metastasis risk in oral squamous cell carcinoma

Qingrong Deng, Yujia Chen, Lisong Lin, Jing Lin, more

Journal of Oral Pathology & Medicine > 52 > 1 > 37 - 46

Background To evaluate whether exosomal circRNAs could serve as diagnostic biomarkers for the accurate preoperative prediction of lymph node metastasis (LNM) risk in oral squamous cell carcinoma (OSCC) patients. Methods A combinative strategy of exosomal circRNAs microarray and qRT‐PCR verification was employed to dig LNM‐related circRNA signatures. Then, a dynamic nomogram was developed based...

article

Deep learning radiomics of ultrasonography for comprehensively predicting tumor and axillary lymph node status after neoadjuvant chemotherapy in breast cancer patients: A multicenter study

Jionghui Gu, Tong Tong, Dong Xu, Fang Cheng, more

Cancer > 129 > 3 > 356 - 366

Background Neoadjuvant chemotherapy (NAC) can downstage tumors and axillary lymph nodes in breast cancer (BC) patients. However, tumors and axillary response to NAC are not parallel and vary among patients. This study aims to explore the feasibility of deep learning radiomics nomogram (DLRN) for independently predicting the status of tumors and lymph node metastasis (LNM) after NAC. Methods In...

article

Surgeon‐performed ultrasound changes surgical management in patients with thyroid cancer

Mario Tapia, Clemente Chia, Jamil Manji, Matthew J. R. Magarey, more

ANZ Journal of Surgery > 92 > 12 > 3268 - 3272

Background A comprehensive neck ultrasound (US) is essential in the operative planning of patients with thyroid disease. Recent literature has shown surgeon‐performed US (SUS) can be more accurate than radiology‐performed US for the purpose of surgical planning. Missed findings on radiology‐performed ultrasound may lead to inadequate surgical management. Methods A retrospective cohort study of...

article

Development and validation of a nomogram for the prediction of lymph node metastasis within 2‐year postoperatively in cT1‐T2N0 oral squamous cell carcinoma

Aoming Cheng, Zhen Wang, Xiaohong Yuan, Huan Liu, more

Head & Neck > 45 > 1 > 103 - 114

Background The current neck management for early oral squamous cell carcinoma (OSCC) has always been a controversial issue. A comprehensive model is necessary for predicting an individual's metastasis risk and appropriate patient counseling. Methods A nomogram for predicting 2‐year LNM in patients with cT1‐2N0 OSCC was developed and validated using clinicopathological data from 642 patients from...

article

Occult metastasis to the superficial level VI lymph nodes in papillary thyroid carcinoma

Ha Na Lee, Chang Myeon Song, Yong Bae Ji, Jae Kyung Myung, more

Head & Neck > 44 > 12 > 2796 - 2802

Background This study aimed to evaluate the incidence and risk factors of occult metastasis to superficial level VI, defined as the space anterior to the strap muscles, including the lymph nodes between the sternocleidomastoid and sternohyoid muscles and suprasternal space lymph nodes. Methods We studied 129 patients with papillary thyroid carcinoma who underwent thyroidectomy and neck dissection,...

article

Superiority of metastatic lymph node ratio over number of node metastases and TNM/AJCC N classification in predicting cancer‐specific survival in medullary thyroid cancer

Andreas Machens, Kerstin Lorenz, Frank Weber, Henning Dralle

Head & Neck > 44 > 12 > 2717 - 2726

Background In medullary thyroid cancer (MTC), it is unclear which nodal classification system, metastatic lymph node ratio (MLNR), number of node metastases, or TNM/AJCC N classification, predicts cancer‐specific survival best. Methods Kaplan–Maier analysis of cancer‐specific survival after operation at a tertiary center. Results Included were 505 MTC patients. The spread of the survival curves...

article

Prognosis of pancreatic head cancer with different patterns of lymph node metastasis

Seung Ki Min, Yunghun You, Dong Wook Choi, In Woong Han, more

Journal of Hepato‐Biliary‐Pancreatic Sciences > 29 > 9 > 1004 - 1013

Background The nodal stage of pancreatic ductal adenocarcinoma (PDAC) is revised in the AJCC 8th edition. Studies on the prognosis of PDAC according to lymph node metastasis (LNM) are still ongoing. We attempted to find the patterns of nodal involvement and to reveal its clinical significance to overall survival (OS). Methods We analyzed 585 patients who received pancreatic head cancer surgery...

article

Optimization of prostate cancer patient lymph node staging via the integration of neutrophil–lymphocyte ratios, platelet–lymphocyte ratios, and ⁶⁸Ga‐PSMA‐PET‐derived SUVmax values

Yinzhao Wang, Yongxiang Tang, Xiaomei Gao, Yu Gan, more

The Prostate > 82 > 15 > 1415 - 1421

Background At present, standardized parameters for quantitatively evaluating ⁶⁸Ga‐PSMA‐PET/CT outcomes when diagnosing lymph node metastasis in prostate cancer patients are lacking. Inflammatory hematological biomarkers offer value as robust predictors of certain cancer‐related outcomes. The present study was thus developed to explore approaches to improving the utility of ⁶⁸Ga‐PSMA‐PET/CT for diagnosing...

article

Development of a novel signature derived from single cell RNA‐sequencing for preoperative prediction of lymph node metastasis in head and neck squamous cell carcinoma

Yibin Dai, Ziyu Wang, Enshi Yan, Jin Li, more

Head & Neck > 44 > 10 > 2171 - 2180

Background Lymph node metastasis (LNM) is considered as an adverse prognostic indicator for cancer patients. Preoperative knowledge of LNM is valuable for pretreatment decision making. Here, we sought to develop and validate an LNM signature for preoperative prediction of LNM in patients with head and neck squamous cell carcinoma (HNSCC). Methods By studying single cell RNA‐sequencing data (scRNA‐seq),...

article

Single‐cell RNA‐seq dissecting heterogeneity of tumor cells and comprehensive dynamics in tumor microenvironment during lymph nodes metastasis in gastric cancer

Yan Qian, Ertao Zhai, Sile Chen, Yinan Liu, more

International Journal of Cancer > 151 > 8 > 1367 - 1381

Lymph node metastasis is the common metastasis route of gastric cancer. However, until now, heterogeneities of tumor cells and tumor microenvironment in primary tumors (PT) and metastatic lymph nodes (MLN) of gastric cancer (GC) remains uncharacterized. In our study, single cell RNA sequencing was performed on tissues from PT and MLN of gastric cancer. Trajectory analysis and function enrichment analyses...

article

SPP1 as a key gene in the lymph node metastasis and a potential predictor of poor prognosis in head and neck carcinoma

Shunli Feng, Wubin Yuan, Zhen Sun, Xiaopeng Guo, more

Journal of Oral Pathology & Medicine > 51 > 7 > 620 - 629

Background Lymph node metastasis (LNM) is an important cause leading to recurrence and development of head and neck carcinoma (HNC), with the precise mechanisms unclear. Thus, we aimed to identify the key genes involved in LNM and further evaluate their expressions and roles. Methods A cohort of HNC in the TCGA was analyzed. The study involved three phases (one screening and two validation phases)...

article

Preoperative Prediction of Axillary Lymph Node Metastasis in Breast Cancer Using CNN Based on Multiparametric MRI

Zijian Wang, Hang Sun, Jing Li, Jing Chen, more

Journal of Magnetic Resonance Imaging > 56 > 3 > 700 - 709

Background Multiparametric magnetic resonance imaging (MRI) is widely used in breast cancer screening. Accurate prediction of the axillary lymph nodes metastasis (ALNM) is essential for breast cancer surgery and treatment. However, there is no mature and effective discerning method for ALNM based on multiparametric MRI. Purpose To evaluate the ALNM using T1‐weighted imaging (T1WI), T2‐weighted...

article

A Nomogram of Combining IVIM‐DWI and MRI Radiomics From the Primary Lesion of Rectal Adenocarcinoma to Assess Nonenlarged Lymph Node Metastasis Preoperatively

Haodong Jia, Xueyan Jiang, Kaiyue Zhang, Jin Shang, more

Journal of Magnetic Resonance Imaging > 56 > 3 > 658 - 667

Background Lymph node (LN) staging plays an important role in treatment decision‐making. Current problem is that preoperative detection of LN involvement is always highly challenging for radiologists. Purpose To explore the value of the nomogram model combining intravoxel incoherent motion diffusion‐weighted imaging (IVIM‐DWI) and radiomics features from the primary lesion of rectal adenocarcinoma...

article

Prognostic and clinicopathological significance of cytocapsular tubes in oral squamous cell carcinoma

Wenjin Wang, Nan Xie, Chen Yi, Ming Zhang, more

Journal of Oral Pathology & Medicine > 51 > 6 > 520 - 528

Background Cytocapsular tubes (CTs) provide membranous channels for cancer cells interconnection and multidirectional locomotion, which facilitate cancer cell transportation and metastasis. However, the clinicopathological significance of CTs has not been documented in oral squamous cell carcinoma (OSCC). Herein, we aimed to identify CTs and assess their clinicopathological significance in OSCC....

article

Clinicopathological predictors of finding additional inguinal lymph node metastases in penile cancer patients after positive dynamic sentinel node biopsy: a European multicentre evaluation

Hielke M. Vries, Hack Jae Lee, Wayne Lam, Rosa S. Djajadiningrat, more

BJU International > 130 > 1 > 126 - 132

Objective To develop a predictive model for additional inguinal lymph node metastases (LNM) at inguinal lymph node dissection (ILND) after positive dynamic sentinel node biopsy (DSNB) using DSNB characteristics to identify a patient group in which ILND might be omitted. Patients and Methods We conducted a retrospective study of 407 inguinal basins with a positive DSNB in penile cancer patients...

article

Magnetic Resonance Imaging‐Based Radiomics Features Associated with Depth of Invasion Predicted Lymph Node Metastasis and Prognosis in Tongue Cancer

Fei Wang, Rukeng Tan, Kun Feng, Jing Hu, more

Journal of Magnetic Resonance Imaging > 56 > 1 > 196 - 209

Background Adequate safe margin in tongue cancer radical surgery is one of the most important prognostic factors. However, the role of peritumoral tissues in predicting lymph node metastasis (LNM) and prognosis using radiomics analysis remains unclear. Purpose To investigate whether magnetic resonance imaging (MRI)‐based radiomics analysis with peritumoral extensions contributes toward the prediction...

article

A model based on endorectal ultrasonography predicts lateral lymph node metastasis in low and middle rectal cancer

Li Yan, Zhou Weifeng, Wang Qin, Wang Jinping

Journal of Clinical Ultrasound > 50 > 5 > 705 - 712

Purpose To investigate the risk factors for lymph node (LN) metastasis in low and middle rectal tumors, construct a predictive model and test the model's diagnostic efficacy. Methods The clinical and pathological data of 172 patients with rectal cancer confirmed by surgery were retrospectively evaluated, among whom 61 patients were finally included in this study. Patients were divided into positive...

article

Predictive value of metastatic lateral lymph node ratio for recurrence in pathologically lateral lymph node‐positive papillary thyroid cancer patients with palpable lymph nodes

Wenwu Dong, Kiyomi Horiuchi, Eiichiro Noguchi, Takahiro Okamoto

Head & Neck > 44 > 7 > 1623 - 1630

Background This study aimed to identify the predictive value of the extent of metastatic lymph nodes in the central and lateral neck compartment for recurrence in papillary thyroid cancer (PTC) patients with pathologically lateral lymph node metastasis (pN1b). Methods This study enrolled 252 patients with pN1b from PTC. Results During a mean follow‐up of 17.6 years, 55 (21.8%) patients experienced...

article

Trends of lymph node sampling and metastasis in pediatric and young adult patients with clear cell, epithelioid, and synovial sarcomas

Jennine H. Weller, Carly Westermann, Palak Patel, Ross M. Beckman, more

Pediatric Blood & Cancer > 69 > 6 > n/a - n/a

Background Clear cell sarcoma of soft tissue (CCS), epithelioid sarcoma, and synovial sarcoma are rare tumors historically identified as high risk for lymph node metastasis. This study investigates incident nodal metastasis and associated survival in children and young adults with these subtypes. Procedure Using the National Cancer Database (2004–2015), we created a retrospective cohort of 1303...

article

The prognostic value of the number of positive lymph nodes and the lymph node ratio in early‐stage cervical cancer

Ester P. Olthof, Constantijne H. Mom, Malou L. H. Snijders, Hans H. B. Wenzel, more

Acta Obstetricia et Gynecologica Scandinavica > 101 > 5 > 550 - 557

Introduction To establish the impact of the number of lymph node metastases (nLNM) and the lymph node ratio (LNR) on survival in patients with early‐stage cervical cancer after surgery. Material and methods In this nationwide historical cohort study, all women diagnosed between 1995 and 2020 with International Federation of Gynecology and Obstetrics (FIGO) 2009 stage IA2–IIA1 cervical cancer and...

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LYMPH NODE METASTASIS (1,377)
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Search results

Exosomal hsa_circRNA_047733 integrated with clinical features for preoperative prediction of lymph node metastasis risk in oral squamous cell carcinoma

Deep learning radiomics of ultrasonography for comprehensively predicting tumor and axillary lymph node status after neoadjuvant chemotherapy in breast cancer patients: A multicenter study

Surgeon‐performed ultrasound changes surgical management in patients with thyroid cancer

Development and validation of a nomogram for the prediction of lymph node metastasis within 2‐year postoperatively in cT1‐T2N0 oral squamous cell carcinoma

Occult metastasis to the superficial level VI lymph nodes in papillary thyroid carcinoma

Superiority of metastatic lymph node ratio over number of node metastases and TNM/AJCC N classification in predicting cancer‐specific survival in medullary thyroid cancer

Prognosis of pancreatic head cancer with different patterns of lymph node metastasis

Optimization of prostate cancer patient lymph node staging via the integration of neutrophil–lymphocyte ratios, platelet–lymphocyte ratios, and ⁶⁸Ga‐PSMA‐PET‐derived SUVmax values

Development of a novel signature derived from single cell RNA‐sequencing for preoperative prediction of lymph node metastasis in head and neck squamous cell carcinoma

Single‐cell RNA‐seq dissecting heterogeneity of tumor cells and comprehensive dynamics in tumor microenvironment during lymph nodes metastasis in gastric cancer

SPP1 as a key gene in the lymph node metastasis and a potential predictor of poor prognosis in head and neck carcinoma

Preoperative Prediction of Axillary Lymph Node Metastasis in Breast Cancer Using CNN Based on Multiparametric MRI

A Nomogram of Combining IVIM‐DWI and MRI Radiomics From the Primary Lesion of Rectal Adenocarcinoma to Assess Nonenlarged Lymph Node Metastasis Preoperatively

Prognostic and clinicopathological significance of cytocapsular tubes in oral squamous cell carcinoma

Clinicopathological predictors of finding additional inguinal lymph node metastases in penile cancer patients after positive dynamic sentinel node biopsy: a European multicentre evaluation

Magnetic Resonance Imaging‐Based Radiomics Features Associated with Depth of Invasion Predicted Lymph Node Metastasis and Prognosis in Tongue Cancer

A model based on endorectal ultrasonography predicts lateral lymph node metastasis in low and middle rectal cancer

Predictive value of metastatic lateral lymph node ratio for recurrence in pathologically lateral lymph node‐positive papillary thyroid cancer patients with palpable lymph nodes

Trends of lymph node sampling and metastasis in pediatric and young adult patients with clear cell, epithelioid, and synovial sarcomas

The prognostic value of the number of positive lymph nodes and the lymph node ratio in early‐stage cervical cancer

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