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Items from 1 to 20 out of 607 results

article

Rendu-Osler-Weber disease: a gastroenterologist’s perspective

Annalisa Tortora, Maria Elena Riccioni, Eleonora Gaetani, Veronica Ojetti, more

Orphanet Journal of Rare Diseases > 2019 > 14 > 1 > 1-4

Hereditary hemorrhagic teleangectasia (HHT, or Rendu-Osler-Weber disease) is a rare inherited syndrome, characterized by arterio-venous malformations (AVMs or Telangiectasia). The most important and common manifestation is nose bleeds (epistaxis). The telangiectasias (small AVMs) are most evident on the lips, tongue, buccal mucosa, face, chest, and fingers, however; large arterio-venous malformations...

article

Retrospective chart review of GI bleeding in people with von Willebrand disease

Jonathan C. Roberts, Miguel A. Escobar, Suchitra Acharya, Nina X. Hwang, more

Haemophilia > 30 > 4 > 970 - 980

Introduction Gastrointestinal (GI) bleeding events (BEs) in von Willebrand disease (VWD) are difficult to diagnose and often recurrent. Limited data from clinical trials has led to lack of consensus on treatment options. Aim Describe current treatments and outcomes for GI BEs in people with VWD. Methods This retrospective, observational, multicentre chart review study was conducted from January...

article

Inhibition of angiogenesis in the management of refractory gastrointestinal bleeding in patients with LVAD support

Sara S. Inglis, Rabea Asleh, Vivek N. Iyer, Sarah D. Schettle, more

Artificial Organs > 48 > 6 > 646 - 654

Background Gastrointestinal bleeding (GIB) in patients with continuous flow left ventricular assist devices (CF‐LVADs) is often related to GI angiodysplasia (GIAD). We previously reported data on VEGF inhibition with IV bevacizumab in the treatment of LVAD‐associated GIAD bleeding, and now present follow‐up data on patients treated with IV bevacizumab and/or low‐dose oral pazopanib. Methods All...

article

Reduced gastrointestinal‐related hospitalisation costs following rescheduling of over‐the‐counter codeine‐containing compound analgesics in Australia: results of a single hospital audit in South Australia

Ryan Mathias, Bejamin Howes, Victoria Cock, Charles Cock

Internal Medicine Journal > 53 > 12 > 2240 - 2246

Background Codeine‐containing compound analgesics (CCCAs) are associated with dependence and, when taken in excess, significant risks of harm. A previous audit showed significant costs related to admissions for gastrointestinal (GI) complications of CCCA. Based on this and other evidence of harm, the Australian Therapeutic Goods Administration changed CCCAs to prescription only in 2018. Aims We...

article

Nonprocedural bleeding after left atrial appendage closure versus direct oral anticoagulants: A subanalysis of the randomized PRAGUE‐17 trial

Marian Branny, Pavel Osmancik, Petr Kala, Martin Poloczek, more

Journal of Cardiovascular Electrophysiology > 34 > 9 > 1885 - 1895

Introduction Observational studies have shown low bleeding rates in patients with atrial fibrillation (AF) treated by left atrial appendage closure (LAAC); however, data from randomized studies are lacking. This study compared bleeding events among patients with AF treated by LAAC and nonvitamin K anticoagulants (NOAC). Methods The Prague‐17 trial was a prospective, multicenter, randomized trial...

article

A novel self‐assembling peptide hemostatic gel as rescue therapy for fistula bleeding after endoscopic ultrasound‐guided hepaticogastrostomy

Kazunari Nakahara, Yosuke Michikawa, Junya Sato, Yosuke Igarashi, more

Journal of Hepato‐Biliary‐Pancreatic Sciences > 30 > 9 > e66 - e67

The novel synthetic self‐assembling peptide PuraStat has been approved for hemostasis in endoscopic procedures. Nakahara and colleagues describe their application of PuraStat for hemostasis of refractory fistula bleeding after endoscopic ultrasound‐guided hepaticogastrostomy. The effective and technically easy procedure is a useful option when hemostasis cannot be achieved by other means.

article

Hemorrhagic duodenal ulcer as a rare complication prior to antiplatelet therapy for Kawasaki disease

Yusuke Hashimoto, Hideki Kumagai, Yuko Okada, Mitsuru Seki, more

Pediatrics International > 65 > 1 > n/a - n/a

article

Risk of hospitalization for upper gastrointestinal bleeding in Helicobacter pylori eradicated patients newly started on warfarin or direct oral anticoagulants: A population‐based cohort study

Fang Jiang, Chengsheng Ju, Chuan‐Guo Guo, Ka Shing Cheung, more

Helicobacter > 28 > 4 > n/a - n/a

Background To investigate risks of hospitalization for upper gastrointestinal bleeding (UGIB) in H. pylori‐eradicated patients newly started on warfarin or direct oral anti‐coagulants (DOACs). Methods We identified all patients who had previously received H. pylori eradication therapy or were found to have no H. pylori on endoscopy and were then newly started on warfarin or DOACs from a population‐based...

article

EUS‐guided coil and glue injection versus endoscopic glue injection for gastric varices: International multicentre propensity‐matched analysis

Jayanta Samanta, Zaheer Nabi, Antonio Facciorusso, Jahnvi Dhar, more

Liver International > 43 > 8 > 1783 - 1792

Background Gastric varices (GVs) are conventionally managed with endoscopic cyanoacrylate (E‐CYA) glue injection. Endoscopic ultrasound (EUS)‐guided therapy using combination of coils and CYA glue (EUS‐CG) is a relatively recent modality. There is limited data comparing the two techniques. Methodology This international multicentre study included patients with GV undergoing endotherapy from two...

article

Role of rifaximin in the management of alcohol‐associated hepatitis: A systematic review and meta‐analysis

Zohaib Ahmed, Joyce Badal, Mohamad Nawras, Dhanushya Battepati, more

Journal of Gastroenterology and Hepatology > 38 > 5 > 703 - 709

Background and Aim Alcohol‐associated hepatitis (AAH) is an acute, inflammatory liver disease with severe short‐term and long‐term morbidity and mortality. AAH can lead to severe complications including hepatic failure, gastrointestinal bleeding, sepsis, and the development or decompensation of cirrhosis. Rifaximin is an antibiotic that reduces bacterial overgrowth and gut translocation, and it may...

article

Clinical outcomes of left atrial appendage occlusion in patients with previous intracranial or gastrointestinal bleeding: Insights from the LOGIC (Left atrial appendage Occlusion in patients with Gastrointestinal or IntraCranial bleeding) International Multicenter Registry

Francesco Gallo, Federico Ronco, Gianpiero D'Amico, Domenico G. Della Rocca, more

Catheterization and Cardiovascular Interventions > 101 > 6 > 1144 - 1153

Aims To compare outcomes of patients who underwent left atrial appendage occlusion (LAAO) for nonvalvular atrial fibrillation (NVAF) and contraindication to anticoagulants due to history of either gastrointestinal (GI) or intracranial (IC) bleeding. Methods Patients with NVAF that underwent LAAO for GI or IC bleeding from seven centers were included in this observational study. Baseline characteristics,...

article

Development and validation of a nomogram for esophagogastric variceal bleeding in liver cirrhosis: A cohort study in 1099 cases

Chun Hua Liu, Shuang Liu, Yong Bing Zhao, Yu Liao, more

Journal of Digestive Diseases > 23 > 10 > 597 - 609

Objectives Esophagogastric variceal bleeding (EVB) is a catastrophic complication of decompensated liver cirrhosis. We aimed to establish a nomogram based on noninvasive clinical and imaging variables to predict the risk of EVB. Methods The cut‐off value of each variable was determined through univariate regression analysis. The least absolute shrinkage and selection operator (LASSO) regression...

article

Retrospective review of secondary prevention strategies for gastrointestinal bleeding and associated clinical outcomes in left ventricular assist device patients

James Ethan Gerrald, Ayesha Ather, Aric Schadler, Emma J. Birks, more

Artificial Organs > 46 > 12 > 2423 - 2431

Background Gastrointestinal bleeding (GIB) is one of the most common bleeding complications associated with left ventricular assist devices (LVAD). Currently, there is no strong evidence or clear guidance for which secondary GIB prophylaxis strategy should be implemented after the discontinuation of aspirin. Methods Our single‐center study describes the outcomes of 26 LVAD patients who experienced...

article

Octa‐nonagenarians can perform video capsule endoscopy safely and with a higher diagnostic yield than 65–79‐year‐old patients

Tamar Thurm, Nathan Gluck, Orly Barak, Liat Deutsch

Journal of the American Geriatrics Society > 70 > 10 > 2958 - 2966

Background Video capsule endoscopy (VCE) is an effective, noninvasive modality for small bowel (SB) investigation. Its usage in the older adults is rising. However, data in octa‐nonagenarians regarding diagnostic yield and motility are lacking. Our aim was to evaluate and compare safety and efficacy of VCE between age subgroups of older adult patients. Methods This was a retrospective study of...

article

Protective effect of proton‐pump inhibitor against gastrointestinal bleeding in patients receiving oral anticoagulants: A systematic review and meta‐analysis

Hyo‐Jeong Ahn, So‐Ryoung Lee, Eue‐Keun Choi, Tae‐Min Rhee, more

British Journal of Clinical Pharmacology > 88 > 11 > 4676 - 4687

Aims The evidence of a protective effect of proton‐pump inhibitor (PPI) in oral anticoagulant (OAC)‐treated patients against gastrointestinal bleeding (GIB) is still lacking. We conducted a meta‐analysis to estimate the risk of GIB in patients with OAC and PPI cotherapy. Methods A systematic search of PubMed, EMBASE, Cochrane and Scopus databases was performed for studies reporting GIB risk in...

article

Neutrophil‐to‐Lymphocyte ratio on admission predicts gastrointestinal bleeding in acute basal ganglia hemorrhage

Xuewei Jiang, Liangliang Zhou, Yinuo Chen, Yuqing Tang, more

Journal of Clinical Laboratory Analysis > 36 > 10 > n/a - n/a

Background Gastrointestinal bleeding (GIB) is a potential contributing factor for poor prognosis of spontaneous basal ganglia hemorrhage (BGH). This study aimed to investigate the predictive value of new inflammatory biomarkers including neutrophil to lymphocytes (NLR) on admission and construct a nomogram for rapidly predicting GIB in acute BGH. Methods The retrospective study included all patients...

article

Endoscopy for the diagnosis and treatment of gastrointestinal bleeding caused by malignancy

Hamzah Abu‐Sbeih, David Szafron, Ahmed A. Elkafrawy, Victor Garcia‐Rodriguez, more

Journal of Gastroenterology and Hepatology > 37 > 10 > 1983 - 1990

Background and Aim The diagnosis and treatment of gastrointestinal (GI) bleeding secondary to malignancy can be challenging. Endoscopy is the gold standard to diagnose and treat gastrointestinal bleeding but clinical characteristics and outcomes of patients with malignancy‐related bleeding are not well understood. This study aims to look at clinical characteristics, endoscopic findings, safety and...

article

Modified N score is helpful for identifying patients who need endoscopic intervention among those with black stools without hematemesis

Nobuhito Ito, Kohei Funasaka, Toshihisa Fujiyoshi, Kazuhiro Furukawa, more

Digestive Endoscopy > 34 > 6 > 1157 - 1165

Objectives Although black stools are one of the signs of upper gastrointestinal bleeding, not all patients without hematemesis need endoscopic intervention. There is no apparent indicator to select who needs treatment thus far. The aim of this study was to establish a novel score that predicts the need for endoscopic intervention in patients with black stools without hematemesis. Methods We retrospectively...

article

Efficacy of intravenous propranolol for life‐threatening diffuse neonatal hemangiomatosis

Takamichi Ishikawa, Keigo Seki, Hiroki Uchiyama

Pediatric Dermatology > 39 > 4 > 613 - 615

Oral propranolol is recommended as the first‐line agent for infantile hemangioma requiring systemic treatment. Life‐threatening complications such as obstructive infantile hemangioma of the airway or infantile hepatic hemangioma associated with high‐output congestive heart failure are major indications for the consideration of early treatment. We present the case of an infant with life‐threatening...

article

Prior oral proton‐pump inhibitor use is associated with reduced severity of aspirin‐related upper gastrointestinal bleeding in older people

Oyekoya T. Ayonrinde, Natasha Walldorf, Nicholas Chan, Nathanael Y. Foo, more

Internal Medicine Journal > 52 > 4 > 663 - 666

Low‐dose aspirin is commonly used for primary or secondary prophylaxis against cardiovascular disease in older people. However, the potential risk of upper gastrointestinal (UGI) ulceration and bleeding associated with low‐dose aspirin use is often not appreciated by prescribers and older consumers. Among 133 serial patients with UGI bleeding, aspirin‐users aged ≥70 years had a ninefold increased...

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GASTROINTESTINAL BLEEDING (607)
ENDOSCOPY (44)
ANGIODYSPLASIA (24)
CAPSULE ENDOSCOPY (20)
EMBOLIZATION (19)
GASTROINTESTINALE BLUTUNG (17)
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HAEMORRHAGE (5)
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Search results

Rendu-Osler-Weber disease: a gastroenterologist’s perspective

Retrospective chart review of GI bleeding in people with von Willebrand disease

Inhibition of angiogenesis in the management of refractory gastrointestinal bleeding in patients with LVAD support

Reduced gastrointestinal‐related hospitalisation costs following rescheduling of over‐the‐counter codeine‐containing compound analgesics in Australia: results of a single hospital audit in South Australia

Nonprocedural bleeding after left atrial appendage closure versus direct oral anticoagulants: A subanalysis of the randomized PRAGUE‐17 trial

A novel self‐assembling peptide hemostatic gel as rescue therapy for fistula bleeding after endoscopic ultrasound‐guided hepaticogastrostomy

Hemorrhagic duodenal ulcer as a rare complication prior to antiplatelet therapy for Kawasaki disease

Risk of hospitalization for upper gastrointestinal bleeding in Helicobacter pylori eradicated patients newly started on warfarin or direct oral anticoagulants: A population‐based cohort study

EUS‐guided coil and glue injection versus endoscopic glue injection for gastric varices: International multicentre propensity‐matched analysis

Role of rifaximin in the management of alcohol‐associated hepatitis: A systematic review and meta‐analysis

Clinical outcomes of left atrial appendage occlusion in patients with previous intracranial or gastrointestinal bleeding: Insights from the LOGIC (Left atrial appendage Occlusion in patients with Gastrointestinal or IntraCranial bleeding) International Multicenter Registry

Development and validation of a nomogram for esophagogastric variceal bleeding in liver cirrhosis: A cohort study in 1099 cases

Retrospective review of secondary prevention strategies for gastrointestinal bleeding and associated clinical outcomes in left ventricular assist device patients

Octa‐nonagenarians can perform video capsule endoscopy safely and with a higher diagnostic yield than 65–79‐year‐old patients

Protective effect of proton‐pump inhibitor against gastrointestinal bleeding in patients receiving oral anticoagulants: A systematic review and meta‐analysis

Neutrophil‐to‐Lymphocyte ratio on admission predicts gastrointestinal bleeding in acute basal ganglia hemorrhage

Endoscopy for the diagnosis and treatment of gastrointestinal bleeding caused by malignancy

Modified N score is helpful for identifying patients who need endoscopic intervention among those with black stools without hematemesis

Efficacy of intravenous propranolol for life‐threatening diffuse neonatal hemangiomatosis

Prior oral proton‐pump inhibitor use is associated with reduced severity of aspirin‐related upper gastrointestinal bleeding in older people

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