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article

Synthesis, spectroscopic and antimicrobial studies of La(III), Ce(III), Sm(III) and Y(III) Metformin HCl chelates

Moamen S. Refat, Fathi M. Al-Azab, Hussein M.A. Al-Maydama, Ragab R. Amin, more

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy > 2015 > 142 > Complete > 392-404

Metal complexes of Metformin hydrochloride were prepared using La(III), Ce(III), Sm(III) and Y(III). The resulting complexes were discussed and synthesized to serve as potential insulin-mimetic. Some physical properties and analytical data of the four complexes were checked. The elemental analysis shows that La(III), Ce(III) Sm(III) and Y(III) formed complexes with Metformin in 1:3 (metal:MF) molar...

article

Antibacterial cellulose membrane via one-step covalent immobilization of ammonium/amine groups

Jianqiang Meng, Xin Zhang, Lei Ni, Zhuo Tang, more

Desalination > 2015 > 359 > Complete > 156-166

This work describes a direct covalent linking of quaternary ammonium salts (QAS) and aminoalkyl groups onto regenerated cellulose (RC) membrane surface to prepare contact active antibacterial membrane materials. The membranes were prepared via alkoxysilane polycondensation reaction with three silane coupling agents, including trimethoxysilylpropyl trimethyl ammonium chloride (QAS _C0 ), trimethoxysilylpropyl...

article

Mechanistic approaches on the antibacterial activity of poly(acrylic acid) copolymers

Günther Gratzl, Sarah Walkner, Sabine Hild, Achim Walter Hassel, more

Colloids and Surfaces B: Biointerfaces > 2015 > 126 > Complete > 98-105

The availability of polymeric antimicrobially active surfaces, which are mainly based on cationic surface effects, is limited. We have previously reported the discovery that, in addition to cationic surfaces, anionic surfaces based on poly(acrylic acid) (PAA) copolymers have a bactericidal effect. In this study, poly(styrene)-poly(acrylic acid)-diblock copolymers (PS-b-PAA) are used to describe the...

article

Poly-guanidinoethylphenylethers organised around a benzene ring: Synthesis and evaluation of their antibacterial and cytotoxic properties

Hugues Massimba Dibama, Maxime Mourer, Raphaël E. Duval, Jean-Bernard Regnouf-de-Vains, more

Bioorganic & Medicinal Chemistry Letters > 2014 > 24 > 20 > 4791-4793

A new family of poly-guanidinium species with a benzene core as the organising agent has been developed. Their antibacterial properties have been evaluated against reference Gram positive and Gram negative bacteria, and their cytotoxicity against eukaryotic cells. Most of these compounds exhibited Minimum Inhibitory Concentrations in the micromolar range.

article

Biological nanosilver particles for the protection of archaeological stones against microbial colonization

Ashraf M.M. Essa, Mohamed K. Khallaf, A.M.M. Essa, M.K. Khallaf

International Biodeterioration & Biodegradation > 2014 > 94 > Complete > 31-37

The inhabitation of microorganisms and their subsequent interaction with mineral matrix of the stone substrate under varied environmental conditions encourages deterioration of stones leading to the loss of strength, durability and aesthetic. This study highlighted the synthesis of nanosilver particles (AgNPs) using the biogenic volatiles of the bacterial strain Nesterenkonia halobia. The antimicrobial...

article

Heavy metal contamination in South African medicinal plants: A cause for concern

A. Okem, C. Southway, W.A. Stirk, R.A. Street, more

South African Journal of Botany > 2014 > 93 > Complete > 125-130

The quality and safety of herbal medicines is becoming a major concern worldwide particularly due to contamination by heavy metals. The present study quantified the levels of heavy metals in frequently used South African medicinal plants and determined the variations in certain biological activities and phytochemical compositions. Eleven plant species were obtained from both muthi shops (MS) (commercial...

article

The triazine-based azo–azomethine dyes; spectroscopy, solvatochromism and biological properties of 2,2′-((2,2′-(6-methoxy-1,3,5-triazine-2,4-diyl) bis(oxy)bis(2,1-phenylene))bis(azan-1-yl-1-ylidene)bis(methan-1-yl-1-ylidene))bis(4-phenyldiazenyl)phenol

Motaleb Ghasemian, Ali Kakanejadifard, Farideh Azarbani, Abedin Zabardasti, more

Journal of Molecular Liquids > 2014 > 195 > Complete > 35-39

The macrocyclic azo–azomethine dyes 2,2′-((2,2′-(6-methoxy-1,3,5-triazine-2,4-diyl) bis(oxy)bis(2,1-phenylene))bis(azan-1-yl-1-ylidene)bis(methan-1-yl-1-ylidene))bis(4-phenyl diazenyl)phenol and its substituted derivatives were synthesized and characterized by elemental analysis, mass, FT-IR, UV, ¹ H and ¹³ С NMR spectroscopy. The solvatochromism of dyes was evaluated in various solvents...

article

Facile in situ synthesis of hydrophilic RGO–CD–Ag supramolecular hybrid and its enhanced antibacterial properties

Tie Li, Jianfeng Shen, Na Li, Mingxin Ye, more

Materials Science & Engineering C > 2014 > 39 > Complete > 352-358

In this study, a novel hydrophilic RGO–CD–Ag hybrid with the supramolecular β-cyclodextrin (CD) as a conjugation interface was fabricated successfully by a facile in situ synthesis process. The results of several characterizations confirmed that the in situ reaction provided a straightforward approach to deposit the CD wrapped Ag nanoparticles onto the CD chemical functionalized RGO sheets through...

article

Bifunctional ethyl 2-amino-4-methylthiazole-5-carboxylate derivatives: Synthesis and in vitro biological evaluation as antimicrobial and anticancer agents

Sherif A.F. Rostom, Hassan M. Faidallah, Mohammed F. Radwan, Mona H. Badr, more

European Journal of Medicinal Chemistry > 2014 > 76 > Complete > 170-181

Thirty thiazole compounds bearing chemotherapeutically-active pharmacophores were synthesized and evaluated for their preliminary in vitro antimicrobial and anticancer activities. Nineteen compounds displayed obvious antibacterial potential, with special bactericidal activity against Gram positive bacteria, whereas, nine analogs showed moderate to weak antifungal activity against Candida albicans...

article

Discovery and optimization of a new class of pyruvate kinase inhibitors as potential therapeutics for the treatment of methicillin-resistant Staphylococcus aureus infections

Nag S. Kumar, Edie M. Dullaghan, B. Brett Finlay, Huansheng Gong, more

Bioorganic & Medicinal Chemistry > 2014 > 22 > 5 > 1708-1725

A novel series of bis-indoles derived from naturally occurring marine alkaloid 4 were synthesized and evaluated as inhibitors of methicillin-resistant Staphylococcus aureus (MRSA) pyruvate kinase (PK). PK is not only critical for bacterial survival which would make it a target for development of novel antibiotics, but it is reported to be one of the most highly connected ‘hub proteins’ in MRSA, and...

article

Application of cross-linked soy protein isolate with resorcinol films for release studies of naturally occurring bioactive agent with antiproliferative activity

G. Siva Mohan Reddy, J. Jayaramudu, E.R. Sadiku, S. Sinha Ray, more

Journal of Drug Delivery Science and Technology > 2014 > 24 > 1 > 86-91

The potential of soy protein isolate films as a release system for naturally occurring antiproliferative agent was investigated. The soy protein isolates was cross linked with resorcinol and the resorcinol content was varied between 10-30 %. The release study was monitored over a period of 24 h at a pH of 7.4. Different kinetic release models were used to determine the mechanism of release of bioactive...

article

Nanotechnology as a therapeutic tool to combat microbial resistance

Robert Y. Pelgrift, Adam J. Friedman, R.Y. Pelgrift, A.J. Friedman

Advanced Drug Delivery Reviews > 2013 > 65 > 13-14 > 1803-1815

Use of nanoparticles is among the most promising strategies to overcome microbial drug resistance. This review article consists of three parts. The first part discusses the epidemiology of microbial drug resistance. The second part describes mechanisms of drug resistance used by microbes. The third part explains how nanoparticles can overcome this resistance, including the following: Nitric oxide-releasing...

article

Gloverins of the silkworm Bombyx mori: Structural and binding properties and activities

Hui-Yu Yi, Xiao-Juan Deng, Wan-Ying Yang, Cong-Zhao Zhou, more

Insect Biochemistry and Molecular Biology > 2013 > 43 > 7 > 612-625

Gloverins are basic, glycine-rich and heat-stable antibacterial proteins (∼14- kDa) in lepidopteran insects with activity against Escherichia coli, Gram-positive bacteria, fungi and a virus. Hyalophora gloveri gloverin adopts a random coil structure in aqueous solution but has α-helical structure in membrane-like environment, and it may interact with the lipid A moiety of lipopolysaccharide (LPS)...

article

Botany, traditional uses, phytochemistry and pharmacology of Waltheria indica L. (syn. Waltheria americana): A review

F. Zongo, C. Ribuot, A. Boumendjel, I. Guissou, more

Journal of Ethnopharmacology > 2013 > 148 > 1 > 14-26

Ethnopharmacological relevance: Waltheria indica L. (syn. Waltheria americana) is commonly used in traditional medicine in Africa, South America and Hawaii, mainly against pain, inflammation, conditions of inflammation, diarrhea, dysentery, conjunctivitis, wounds, abscess, epilepsy, convulsions, anemia, erectile dysfunctions, bladder ailments and asthma. Aim of the review to provide an up-to-date...

article

Evaluation of Antibacterial Activity and Phytochemical Screening of Wrightia tinctoria L.

S. Ravi Shankar, R. Rangarajan, D.V.L. Sarada, C. Sreenath Kumar, more

Pharmacognosy Journal > 2010 > 2 > 14 > 19-22

Wrightia tinctoria L. leaf hexane, methanol, chloroform, ethyl acetate and water extracts were screened against plant pathogenic bacteria by in vitro. The extracts were tested using disc diffusion method and minimum inhibitory concentration. Ethyl acetate and methanol extracts showed significant antibacterial activity against gram negative bacteria; the MIC was 50 μg/ml for Xanthomonas campestris...

article

Copper oxide–ferric oxide nanocomposite: Synthesis, characterization, and antibacterial and antifungal properties

Mohamed Elnouby, Marwa Nabil, Abdulaziz A. Al-Askar, Przemysław Kowalczewski, more

Materials Science Poland > 2024 > Vol. 42, No. 3 > 100--110

Recently, copper oxide–ferric oxide nanocomposites (CuO/Fe₂O₃-NCs) have gained popularity and are widely employed in various applications. However, their effectiveness against phytopathogens has not been studied yet. This study investigates the synthesis and characterization of CuO/Fe₂O₃-NCs using the hydrothermal technique. X-ray diffraction (XRD), transmission electron microscopy (TEM), energy-dispersive...

article

Coaxial 3D Printing Scaffolds with Sequential Antibacterial and Osteogenic Functions to Effectively Repair Infected Mandibular Defects

Hui Zhang, Huan Sun, Linli Zhang, Boqing Zhang, more

Advanced Functional Materials > 34 > 44 > n/a - n/a

Infected mandibular defects pose a formidable challenge without an entirely satisfactory repair strategy. Here, a coaxial 3D printing scaffold comprising a shell loaded is dveloped with the antibiotic minocycline hydrochloride and a core wrapped with traditional Chinese medicine antler powers. This study is conducted to evaluate the efficacy of the scaffold in facilitating the repair of infected mandibular...

article

Joint Exfoliation of MXene by Dimensional Mismatched SiC/ZIF‐67 Toward Multifunctional Flame Retardant Thermoplastic Polyurethane

Xue Bi, Kunpeng Song, Zeqi Zhang, Tao Lin, more

Small > 20 > 43 > n/a - n/a

The single‐layer MXene fully demonstrates the advantages of 2D materials, especially catalytic, conductive, and mechanical properties. However, the high energy consumption and low efficiency faced by MXene in the divestiture process are still challenges that need to be solved urgently. In this article, dimension mismatch and collaborative stripping strategies are skillfully combined to easily realize...

article

Dyeing and Performance Testing of Chitosan-Modified Cotton Fabrics with Tea Polyphenols

Lixue Zhao, Chunyan Zhu, Yanping Lin, Chen Yang

Fibres & Textiles in Eastern Europe > 2024 > Vol. 32, no. 4 > 22--30

Tea polyphenols are one of the primary components of tea leaves and possess various beneficial effects, including radiation resistance, detoxification, antioxidation, antibacterial properties, anti-aging effects, digestive support, anti-cancer properties, and immune system enhancement. This study focuses on utilizing tea polyphenols for the functional finishing of chitosan-modified cotton fabrics,...

article

A Sunlight‐Driven Self‐Cleaning CuCo‐MOF Composite Membrane for Highly Efficient Emulsion Separation and Water Purification

Xuanting He, Zixuan Wu, Jihan Lu, Jiaxiang Liu, more

Small > 20 > 42 > n/a - n/a

The fouling phenomenon of membranes has hindered the rapid development of separation technology in wastewater treatment. The integration of materials into membranes with both excellent separation performance and self‐cleaning properties still pose challenges. Here, a self‐assembled composite membrane with solar‐driven self‐cleaning performance is reported for the treatment of complex oil‐water emulsions...

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Search results

Synthesis, spectroscopic and antimicrobial studies of La(III), Ce(III), Sm(III) and Y(III) Metformin HCl chelates

Antibacterial cellulose membrane via one-step covalent immobilization of ammonium/amine groups

Mechanistic approaches on the antibacterial activity of poly(acrylic acid) copolymers

Poly-guanidinoethylphenylethers organised around a benzene ring: Synthesis and evaluation of their antibacterial and cytotoxic properties

Biological nanosilver particles for the protection of archaeological stones against microbial colonization

Heavy metal contamination in South African medicinal plants: A cause for concern

The triazine-based azo–azomethine dyes; spectroscopy, solvatochromism and biological properties of 2,2′-((2,2′-(6-methoxy-1,3,5-triazine-2,4-diyl) bis(oxy)bis(2,1-phenylene))bis(azan-1-yl-1-ylidene)bis(methan-1-yl-1-ylidene))bis(4-phenyldiazenyl)phenol

Facile in situ synthesis of hydrophilic RGO–CD–Ag supramolecular hybrid and its enhanced antibacterial properties

Bifunctional ethyl 2-amino-4-methylthiazole-5-carboxylate derivatives: Synthesis and in vitro biological evaluation as antimicrobial and anticancer agents

Discovery and optimization of a new class of pyruvate kinase inhibitors as potential therapeutics for the treatment of methicillin-resistant Staphylococcus aureus infections

Application of cross-linked soy protein isolate with resorcinol films for release studies of naturally occurring bioactive agent with antiproliferative activity

Nanotechnology as a therapeutic tool to combat microbial resistance

Gloverins of the silkworm Bombyx mori: Structural and binding properties and activities

Botany, traditional uses, phytochemistry and pharmacology of Waltheria indica L. (syn. Waltheria americana): A review

Evaluation of Antibacterial Activity and Phytochemical Screening of Wrightia tinctoria L.

Copper oxide–ferric oxide nanocomposite: Synthesis, characterization, and antibacterial and antifungal properties

Coaxial 3D Printing Scaffolds with Sequential Antibacterial and Osteogenic Functions to Effectively Repair Infected Mandibular Defects

Joint Exfoliation of MXene by Dimensional Mismatched SiC/ZIF‐67 Toward Multifunctional Flame Retardant Thermoplastic Polyurethane

Dyeing and Performance Testing of Chitosan-Modified Cotton Fabrics with Tea Polyphenols

A Sunlight‐Driven Self‐Cleaning CuCo‐MOF Composite Membrane for Highly Efficient Emulsion Separation and Water Purification

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