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article

Robotic Adrenalectomy

Orhan Agcaoglu, Ozer Makay

Current Surgery Reports > 2019 > 7 > 9 > 1-7

Purpose Even though laparoscopy is still the gold standard technique of adrenal surgery, many of the recent reports noted the safety and efficacy of robotics. However, there are still scant data and debates regarding outcomes of robotics in adrenal surgery. The aim of this review was to discuss recent literature and provide institutional experience on robotic adrenalectomy. Recent Findings Due to...

article

Retrospective analysis of variant venous anatomy in 303 laparoscopic adrenalectomies and its clinical implications

Fukang Sun, Ran Zhuo, Wenming Ma, Hongchao He, more

Journal of Surgical Oncology > 119 > 6 > 801 - 806

Background and objectives To clarify the correlation of variant venous anatomy with adrenal tumor phenotype and surgical outcomes. Patients and methods This retrospective study included 303 consecutive minimally invasive adrenalectomies from 301 patients. All adrenal veins were identified. We compared the preoperative, intraoperative, and postoperative data between patients with and without variant...

article

A rare case of pure testosterone-secreting adrenal adenoma in a postmenopausal elderly woman

Wei-bin Zhou, Nan Chen, Cheng-jiang Li

BMC Endocrine Disorders > 2019 > 19 > 1 > 1-5

Background Hyperandrogenemia is more common in puberty and reproductive age, but relatively rare in postmenopausal women. Postmenopausal virilization may result from androgen-producing tumors. Androgen-secreting adrenal tumors are rare in clinical practice and are diagnosed as adrenocortical carcinoma, most of which can co-secrete androgen and cortisol. Highly elevated serum testosterone level with...

article

An update on adrenal endocrinology: significant discoveries in the last 10 years and where the field is heading in the next decade

Crystal D. C. Kamilaris, Constantine A. Stratakis

Hormones > 2018 > 17 > 4 > 479-490

The last 10 years have produced an amazing number of significant discoveries in the field of adrenal endocrinology. The development of the adrenal gland was linked to specific molecules. Cortisol-producing lesions were associated mostly with defects of the cyclic AMP (cAMP) signaling pathway, whereas aldosterone-producing lesions were found to be the result of defects in aldosterone biosynthesis or...

article

Giant nonfunctioning adrenal tumors: two case reports and review of the literature

George Chatzoulis, Ioannis Passos, Dimitra-Rafailia Bakaloudi, Dimitrios Giannakidis, more

Journal of Medical Case Reports > 2018 > 12 > 1 > 1-6

Background There are an estimated 1–2 cases per million per year of adrenocortical carcinoma in the USA. It represents a rare and aggressive malignancy; it is the second most aggressive endocrine malignant disease after anaplastic thyroid carcinoma. Non-secretory adrenal masses are diagnosed late due to a mass effect or metastatic disease or found incidentally (adrenal incidentalomas). Case presentation...

article

The role of microRNAs in the pathophysiology of adrenal tumors

Nunki Hassan, Jing Ting Zhao, Stan B. Sidhu

Molecular and Cellular Endocrinology > 2017 > 456 > C > 36-43

MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression in a sequence-specific manner. Due to its association with an assortment of diseases, miRNAs have been extensively studied in the last decade. In this review, the current understanding of the role of miRNAs in the pathophysiology of adrenal tumors is discussed. The recent contributions of high-throughput miRNA profiling studies...

article

Diagnostic and prognostic role of SF1, IGF2, Ki67, p53, adiponectin, and leptin receptors in human adrenal cortical tumors

Anna Babińska, Rafał Pęksa, Piotr Wiśniewski, Renata Świątkowska‐Stodulska, more

Journal of Surgical Oncology > 116 > 3 > 427 - 433

Background The authors have examined the immunohistochemical expression of several proteins and their relationship with adrenal cortical carcinoma (ACC) diagnosis and progression. Materials and Methods A total of 83 patients with benign and malignant adrenal cortex tumors operated on in a single center were included in the study. Expression of the following proteins was examined: steroidogenic...

article

Additional value of hybrid SPECT/CT systems in neuroendocrine tumors, adrenal tumors, pheochromocytomas and paragangliomas

K.K. Wong, S. Chondrogiannis, D. Fuster, C. Ruiz, more

Revista Espa�ola de Medicina Nuclear e Imagen Molecular (English Edition) > 2017 > 36 > 2 > 103-109

The aim of this review was to evaluate the potential advantages of SPECT/CT hybrid imaging in the management of neuroendocrine tumors, adrenal tumors, pheochromocytomas and paragangliomas. From the collected data, the superiority of fused images was observed as providing both functional/molecular and morphological imaging compared to planar imaging. This provided an improvement in diagnostic imaging,...

article

Imaging findings of adrenal primitive neuroectodermal tumors: a series of seven cases

Y. Zhang, P. Cai, M. Chen, X. Yi, more

Clinical and Translational Oncology > 2017 > 19 > 5 > 641-649

Objective To explore the imaging features of adrenal primitive neuroectodermal tumors (PNETs). Materials and methods This retrospective study included seven patients with surgically and pathologically confirmed adrenal PNETs. Among them, six underwent computed tomography (CT) scans, and one underwent magnetic resonance imaging. The imaging findings, including size, shape, margin, hemorrhage, calcification,...

article

Pediatric adrenal cortical carcinomas: Histopathological criteria and clinical trials. A systematic review

Xia Xu, Consolato Sergi

Contemporary Clinical Trials > 2016 > 50 > C > 37-44

Adrenal tumors are quite rare in infancy and childhood with the exception of neuroblastoma. In fact, adrenocortical tumors (ACT) account for only 0.2% of all malignant cancers in children and adolescents. According to a multicenter registry investigation, the median interval between first endocrine symptoms and the diagnosis of ACT is 5months, and death is seen in 38% of patients, who suffer from...

article

Adrenal tumors in children – Clinicopathological experience

Gite Vandana, Dhakane Maruti

Apollo Medicine > 2016 > 13 > 2 > 118-122

To document general baseline data on the patterns of childhood adrenal tumors.This is a retrospective analysis of 10 cases of pediatric adrenal tumors (age group 0–12 years) in surgical pathology encountered over a period of 5 years.In the adrenal gland, adrenal medullary tumors were more common than adrenal cortex with neuroblastoma as common individual tumor. Two were tumors of adrenal cortex and...

article

Management of adrenal incidentaloma by laparoscopic transperitoneal anterior and submesocolic approach

Alessandro M. Paganini, Mario Guerrieri, Andrea Balla, Silvia Quaresima, more

Langenbeck's Archives of Surgery > 2016 > 401 > 1 > 71-79

Purpose Laparoscopic adrenalectomy (LA) is becoming the main approach for incidentally discovered adrenal masses (adrenal incidentaloma (AI)). The aim of this study was to evaluate the results of LA with a transperitoneal anterior approach for right adrenal lesions and either a transperitoneal anterior or transperitoneal anterior submesocolic approach for the left-sided lesions. Methods The study...

article

Cystic adrenal lesions: Clinical and surgical management. The experience of a referral centre

Giuseppe Cavallaro, Daniele Crocetti, Annalisa Paliotta, Antonietta De Gori, more

International Journal of Surgery > 2015 > 13 > Complete > 23-26

Background: Cystic adrenal lesions (CALs) represent a rare entity having heterogeneity in etiology and clinical manifestations. Due to their very low incidence and heterogeneity in clinical aspects, many controversials still exist about their management. Methods: From 1984 to 2012, 21 patients (7 M, 14 F, mean age 48.2 years) underwent adrenalectomy for CALs. 9 patients suffered from hypertension,...

article

Posterior retroperitoneoscopic versus laparoscopic adrenalectomy in sporadic and MENIIA pheochromocytomas

Andreas Kiriakopoulos, Athanassios Petralias, Dimitrios Linos

Surgical Endoscopy > 2015 > 29 > 8 > 2164-2170

Introduction Retroperitoneal adrenalectomy (PRA) comprises an alternative approach in the management of adrenal tumors that has been set as the treatment of choice in our Institution. We assess the impact of PRA the management of hereditary and sporadic pheochromocytomas comparing its outcomes to the laparoscopic technique, in a case–controlled setting. Patients and methods From May 2008 to January...

article

Laparoscopic transperitoneal anterior adrenalectomy in pheochromocytoma: experience in 62 patients

Alessandro M. Paganini, Andrea Balla, Mario Guerrieri, Giovanni Lezoche, more

Surgical Endoscopy > 2014 > 28 > 9 > 2683-2689

Background Aim was to evaluate the results in 62 patients undergoing laparoscopic adrenalectomy (LA) for the treatment of pheochromocytoma (PHE), with a transperitoneal anterior approach for lesions on the right side, and with a transperitoneal anterior submesocolic approach in case of left-sided lesions. Methods Sixty-two patients underwent LA for the treatment of PHE at two centers in Rome and...

article

Imaging features of adrenal ganglioneuroma: a case report

Anass Mohammed Majbar, Sanae Elmouhadi, Mouna Elaloui, Mohamed Raiss, more

BMC Research Notes > 2014 > 7 > 1 > 1-4

Background Adrenal ganglioneuroma is a rare tumor constituting 20–30% of all ganglioneuromas. It is a benign tumor and can present diagnostic problems when confused with other adrenal solid tumors. Case presentation We herein report a case of adrenal ganglioneuroma in a 28-year-old Arabic patient and emphasize the diagnostic role of cross-sectional imaging modalities (computed tomography and magnetic...

article

Simultaneous pheochromocytoma and third‐degree atrioventricular block in 2 dogs

Genevieve Mak, Justin Allen

Journal of Veterinary Emergency and Critical Care > 23 > 6 > 610 - 614

ObjectiveTo describe the occurrence of pheochromocytoma with third‐degree atrioventricular (AV) block in 2 dogs. Case Series SummaryTwo dogs were referred for echocardiograms and further diagnostic and therapeutic treatment for third‐degree AV block. Abdominal ultrasound of 1 dog revealed an adrenal mass, while that of the other dog revealed bilateral adrenal masses. While undergoing treatment, 1...

article

Minimally invasive surgery for malignant adrenal tumors

Antonio Toniato

The Surgeon > 2013 > 11 > 5 > 253-257

The increasingly widespread use of minimally invasive surgery has allowed surgeons to exploit this approach for malignant adrenal tumors, though its actual role remains debated. The purpose of this study was to ascertain whether minimally-invasive surgery is a safe and effective treatment for adrenal carcinoma and metastases.Demographic and clinical data were prospectively entered in a computerized...

article

The utility of cortical-sparing adrenalectomy in pheochromocytomas associated with genetic syndromes

Sara C. Fallon, Daniel Feig, Monica E. Lopez, Mary L. Brandt

Journal of Pediatric Surgery > 2013 > 48 > 6 > 1422-1425

Management of pediatric patients with pheochromocytomas associated with genetic syndromes, such as Von Hippel-Lindau (VHL) disease, is complex owing to the need for continuous surveillance, high rates of recurrence, multiple operations during childhood, and the possibility of lifelong exogenous steroid replacement. We report the successful treatment of two siblings with VHL who underwent a total of...

article

Laparoscopic Adrenalectomy: The Transperitoneal Approach

Julian C. Y. Ip, James C. Lee, Stanley B. Sidhu

Current Surgery Reports > 2013 > 1 > 1 > 26-33

Laparoscopic adrenalectomy (LA) has become the gold standard in the operative approach to tumors of the adrenal gland. It has been 20 years since it was first described in the literature and the technique has afforded improved operative and perioperative outcomes compared to the open approach to the adrenal gland. These include improved cosmesis, less post-operative pain, and reduced morbidity, and...

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Search results

Robotic Adrenalectomy

Retrospective analysis of variant venous anatomy in 303 laparoscopic adrenalectomies and its clinical implications

A rare case of pure testosterone-secreting adrenal adenoma in a postmenopausal elderly woman

An update on adrenal endocrinology: significant discoveries in the last 10 years and where the field is heading in the next decade

Giant nonfunctioning adrenal tumors: two case reports and review of the literature

The role of microRNAs in the pathophysiology of adrenal tumors

Diagnostic and prognostic role of SF1, IGF2, Ki67, p53, adiponectin, and leptin receptors in human adrenal cortical tumors

Additional value of hybrid SPECT/CT systems in neuroendocrine tumors, adrenal tumors, pheochromocytomas and paragangliomas

Imaging findings of adrenal primitive neuroectodermal tumors: a series of seven cases

Pediatric adrenal cortical carcinomas: Histopathological criteria and clinical trials. A systematic review

Adrenal tumors in children – Clinicopathological experience

Management of adrenal incidentaloma by laparoscopic transperitoneal anterior and submesocolic approach

Cystic adrenal lesions: Clinical and surgical management. The experience of a referral centre

Posterior retroperitoneoscopic versus laparoscopic adrenalectomy in sporadic and MENIIA pheochromocytomas

Laparoscopic transperitoneal anterior adrenalectomy in pheochromocytoma: experience in 62 patients

Imaging features of adrenal ganglioneuroma: a case report

Simultaneous pheochromocytoma and third‐degree atrioventricular block in 2 dogs

Minimally invasive surgery for malignant adrenal tumors

The utility of cortical-sparing adrenalectomy in pheochromocytomas associated with genetic syndromes

Laparoscopic Adrenalectomy: The Transperitoneal Approach

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