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Items from 1 to 20 out of 1,533 results

article

Roux‐en‐Y drainage of a pancreatic fistula for disconnected pancreatic duct syndrome after acute necrotizing pancreatitis

Erik G. Pearson, Courtney L. Scaife, Sean J. Mulvihill, Robert E. Glasgow

HPB > 14 > 1 > 26 - 31

Background: After acute necrotizing pancreatitis (ANP), a pancreatic fistula may occur from disconnected pancreatic duct syndrome (DPDS) where a segment of the pancreas is no longer in continuity with the main pancreatic duct. Aim: To study the outcome of patients treated using Roux‐Y pancreatic fistula tract‐jejunostomy for DPDS after ANP. Methods: Between 2002 and 2011, patients treated for DPDS...

article

Acute pancreatitis

Deanne Bell, Margaret G. Keane, Stephen P. Pereira, D. Bell, more

Medicine > 2015 > 43 > 3 > 174-181

Acute pancreatitis is an inflammatory condition with a variable clinical course. Diagnosis is based upon clinical presentation, laboratory indices and imaging studies, whilst illness severity can be assessed by clinical scoring systems, such as the Ranson, Glasgow or APACHE II criteria, or by radiological assessments such as the CT severity index. Most patients develop self-limiting disease but a...

article

Primary angiosarcoma of the pancreas mimicking severe acute pancreatitis – Case report

Adrienn Csiszkó, István László, Károly Palatka, Károly Gábor Szabó, more

Pancreatology > 2015 > 15 > 1 > 84-87

Primary angiosarcoma of the pancreas is an extremely rare neoplasm that often mimicks severe acute pancreatitis.A 58-year-old man was admitted with clinical and laboratory signs of severe acute pancreatitis. Contrast enhanced CT scan demonstrated haemorrhagic necrotizing inflammation of the pancreas involving the pancreatic tail, splenic hilum and small bowels with multiple peripancreatic and free...

article

All-trans-retinoic acid induced acute pancreatitis: a single or multifactorial association?

Rodrigo Lopes da Silva

International Journal of Hematology > 2011 > 93 > 4 > 561-562

article

Effects of integrated traditional Chinese and Western medicine for acute pancreatitis: A real‐world study in a tertiary teaching hospital

Lihui Deng, Zhiyao Chen, Ping Zhu, Cheng Hu, more

Journal of Evidence‐Based Medicine > 17 > 3 > 575 - 587

Aim This study aimed to evaluate whether integrated traditional Chinese medicine (TCM) and Western medicine (WM) is more effective than WM for acute pancreatitis (AP). Methods Patients with AP were enrolled and divided into the TCM and WM (TCM&WM) and WM groups according to the therapeutic protocol in real clinical settings. We applied 1:3 propensity score matching, which was to adjust confounding...

article

Association between diabetic status and risk of acute pancreatitis: A nationwide population‐based study

Kwang Hyun Chung, In Rae Cho, Young Hoon Choi, Young Deok Cho, more

Journal of Evidence‐Based Medicine > 17 > 3 > 588 - 596

Objective There have been several epidemiologic studies on the association between diabetes mellitus and acute pancreatitis. However, there is no solid evidence, and the effect of diabetes mellitus severity on acute pancreatitis incidence is not well known. This study aimed to evaluate the association between diabetic status and the risk of acute pancreatitis in a nationwide population‐based cohort...

article

Association between gut microbiota and acute pancreatitis: a bidirectional Mendelian randomization study

Feng Zhou, Yang Liu, Yanqing Shi, Nanzhen Wu, more

Journal of Gastroenterology and Hepatology > 39 > 9 > 1895 - 1902

Background and Aim The dysbiosis of gut microbiota has been reported in acute pancreatitis. However, the direction and magnitude between host microbiota and pancreas remains to be established. This study investigated the association between gut microbiota and acute pancreatitis using Mendelian randomization (MR) methods. Methods Summary statistics of gut microbiota abundance and acute pancreatitis...

article

Precise Control of Metal Active Sites of Metal–Organic Framework Nanozymes for Achieving Excellent Enzyme‐Like Activity and Efficient Pancreatitis Therapy

Jie Zhang, Meilin Guo, Qikuan He, Zhisen Zhang, more

Small > 20 > 32 > n/a - n/a

Acute pancreatitis (AP) is a potentially life‐threatening inflammatory disease that can lead to the development of systemic inflammatory response syndrome and its progression to severe acute pancreatitis. Hence, there is an urgent need for the rational design of highly efficient antioxidants to treat AP. Herein, an optimized Cu‐based metal–organic framework (MOF) nanozyme with exceptional antioxidant...

article

Pancreatitis in cystic fibrosis: Presentation, medical and surgical management, and the impact of modulator therapies

Reza V. Milano, Kayla Morneault‐Gill, Hebat Y. Kamal, Jodie A. Barkin, more

Pediatric Pulmonology > 59 > S1 > S53 - S60

Patients with Cystic Fibrosis (CF) are at increased risk of acute (AP) and chronic (CP) pancreatitis, and their complications. The extent of remaining healthy pancreatic parenchyma determines the risk of developing future episodes of pancreatitis, as well as pancreatic exocrine or endocrine insufficiency. Pancreatitis may be the presenting symptom of CF, and genetic testing is especially important...

article

Prevalence, treatment efficacy, and risk factors of vascular complications in acute pancreatitis: A case–control study

Xu Guo, Huan Tong, Liu Xiang Chen, Meng Juan Wu, more

Journal of Digestive Diseases > 25 > 5 > 318 - 327

Objective We aimed to investigate the prevalence of vascular complications in acute pancreatitis (AP), to compare patient outcomes using various treatments, and to explore the related risk factors. Methods Consecutive AP patients admitted from January 2010 to July 2017 were retrospectively included. Demographics, vascular complications, laboratory indices, and imaging findings were collected. Univariate...

article

Saikosaponin d protects pancreatic acinar cells against cerulein‐induced pyroptosis through alleviating mitochondrial damage and inhibiting cGAS‐STING pathway

Hui Chen, Xirong Lu, Beiqi Xu, Gang Cheng, more

Journal of Applied Toxicology > 44 > 7 > 1005 - 1013

Acute pancreatitis represents an inflammatory disease featuring pancreatic necrosis and inflammation. Inflammatory injury of pancreatic acinar cells (PACs) is critically involved in the initiation and progression of acute pancreatitis. Pyroptosis, a new kind of programmed cell death concomitant with a low‐grade inflammatory reaction, plays a function in acute pancreatitis pathology. It is unclear...

article

Risk of acute pancreatitis among new users of empagliflozin compared to sulfonylureas in patients with type 2 diabetes: A post‐authorization safety study

Soulmaz Fazeli Farsani, Kristy Iglay, Ling Zhang, Christian Niyonkuru, more

Pharmacoepidemiology and Drug Safety > 33 > 5 > n/a - n/a

Purpose This study was undertaken to evaluate the potential risk of acute pancreatitis with empagliflozin in patients with type 2 diabetes (T2D) newly initiating empagliflozin. Methods Data from two large US claims databases were analyzed in an observational study of patients with T2D receiving metformin who were newly prescribed empagliflozin versus sulfonylurea (SU). Because dipeptidyl peptidase‐4...

article

Calcium administration appears not to benefit acute pancreatitis patients with hypocalcemia

Tianao Yan, Yifei Ma, Zheng Wang, Jun Lyu, more

Journal of Hepato‐Biliary‐Pancreatic Sciences > 31 > 4 > 273 - 283

Objective Hypocalcemia occurs commonly among patients with acute pancreatitis (AP) in the intensive care unit (ICU). Calcium therapy could be used to correct hypocalcemia and maintain calcium levels, but its impact on the prognosis has not been demonstrated. Our study aimed to determine whether calcium therapy could benefit the multiple outcomes of AP patients with hypocalcemia. Methods We extracted...

article

Development of pancreatic diseases during long‐term follow‐up after acute pancreatitis: a post‐hoc analysis of a prospective multicenter cohort

FEM Rijk, NJ Sissingh, TT Boel, HC Timmerhuis, more

Journal of Gastroenterology and Hepatology > 39 > 4 > 674 - 684

Background and Aim More insight into the incidence of and factors associated with progression following a first episode of acute pancreatitis (AP) would offer opportunities for improvements in disease management and patient counseling. Methods A long‐term post hoc analysis of a prospective cohort of patients with AP (2008–2015) was performed. Primary endpoints were recurrent acute pancreatitis...

article

The role of CFTR in diabetes‐induced pancreatic ductal dysfunction

Oleg V. Gerasimenko, Julia V. Gerasimenko

The Journal of Physiology > 602 > 6 > 993 - 994

article

Serum lipase in acute pancreatitis associated with hypertriglyceridaemia

Adam Morton

Internal Medicine Journal > 54 > 3 > 491 - 493

The incidence of hypertriglyceridaemic pancreatitis is increasing. Hypertriglyceridaemia may be associated with false lowering of serum amylase and lipase in vitro. A retrospective study of serum lipase levels in 26 individuals who had acute pancreatitis diagnosed based on clinical criteria together with changes on computer tomography in the setting of severe hypertriglyceridaemia over a 5‐year period...

article

Acute pancreatitis in childhood – a comparative international study and tale of two cities

Adeline Salim, Ampaipan Boonthai, Pornthep Tanpowpong, Paul D. Losty

ANZ Journal of Surgery > 94 > 1-2 > 215 - 221

Backgrounds To compare factor(s) contributing to aetiology, management and clinical outcome(s) of paediatric patients acquiring acute pancreatitis (AP) at two major university paediatric surgical centres in Liverpool and Bangkok. Methods All patients (<18 years) with an index diagnosis of AP (ICD 10 coding) during 2006–2016 were studied. Results 121 patients included n = 79 (65.3%) in Thailand...

article

Prognostic significance of organ failure and infected pancreatic necrosis in acute pancreatitis: An updated systematic review and meta‐analysis

Wen Mo Hu, Tian Rui Hua, Yue Lun Zhang, Guo Rong Chen, more

Journal of Digestive Diseases > 24 > 12 > 648 - 659

Objectives In patients with acute pancreatitis (AP), minimally invasive treatment and the step‐up approach have been widely used to deal with infected pancreatic necrosis (IPN) in the last decade. It is unclear whether IPN has become a less important determinant of mortality relative to organ failure (OF). We aimed to statistically aggregate recent evidence from published studies to determine the...

article

The risk of recurrent pancreatitis after first episode of acute pancreatitis in relation to etiology and severity of disease: A systematic review, meta‐analysis and meta‐regression analysis

Shahab Hajibandeh, Rebecca Jurdon, Emily Heaton, Shahin Hajibandeh, more

Journal of Gastroenterology and Hepatology > 38 > 10 > 1718 - 1733

Background and Aim The study aims to determine and quantify the stratified risk of recurrent pancreatitis (RP) after the first episode of acute pancreatitis in relation to etiology and severity of disease. Methods A systematic review and meta‐analysis in compliance with PRISMA statement standards was conducted. A search of electronic information sources was conducted to identify all studies investigating...

article

Evaluation of red blood cell distribution width, neutrophil‐to‐lymphocyte ratio, and other hematologic parameters in canine acute pancreatitis

Meghan M. Johnson, John C. Gicking, Deborah A. Keys

Journal of Veterinary Emergency and Critical Care > 33 > 5 > 587 - 597

Objective To determine if RBC distribution width (RDW), neutrophil‐to‐lymphocyte ratio (NLR), and other hematological parameters are associated with increased odds of in‐hospital mortality, increased length of hospitalization (LOH), or disease severity as measured by the Canine Acute Pancreatitis Severity (CAPS) score in dogs with acute pancreatitis (AP). Design Retrospective, multicenter study...

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ACUTE PANCREATITIS (1,533)
CHRONIC PANCREATITIS (79)
SEVERITY (54)
PANCREAS (53)
INFLAMMATION (50)
RAT (48)
PANCREATIC NECROSIS (45)
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ERCP (13)
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GHRELIN (12)
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PANCREATIC PSEUDOCYST (12)
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TNF-Α (10)
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CFTR (9)
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Search results

Roux‐en‐Y drainage of a pancreatic fistula for disconnected pancreatic duct syndrome after acute necrotizing pancreatitis

Acute pancreatitis

Primary angiosarcoma of the pancreas mimicking severe acute pancreatitis – Case report

All-trans-retinoic acid induced acute pancreatitis: a single or multifactorial association?

Effects of integrated traditional Chinese and Western medicine for acute pancreatitis: A real‐world study in a tertiary teaching hospital

Association between diabetic status and risk of acute pancreatitis: A nationwide population‐based study

Association between gut microbiota and acute pancreatitis: a bidirectional Mendelian randomization study

Precise Control of Metal Active Sites of Metal–Organic Framework Nanozymes for Achieving Excellent Enzyme‐Like Activity and Efficient Pancreatitis Therapy

Pancreatitis in cystic fibrosis: Presentation, medical and surgical management, and the impact of modulator therapies

Prevalence, treatment efficacy, and risk factors of vascular complications in acute pancreatitis: A case–control study

Saikosaponin d protects pancreatic acinar cells against cerulein‐induced pyroptosis through alleviating mitochondrial damage and inhibiting cGAS‐STING pathway

Risk of acute pancreatitis among new users of empagliflozin compared to sulfonylureas in patients with type 2 diabetes: A post‐authorization safety study

Calcium administration appears not to benefit acute pancreatitis patients with hypocalcemia

Development of pancreatic diseases during long‐term follow‐up after acute pancreatitis: a post‐hoc analysis of a prospective multicenter cohort

The role of CFTR in diabetes‐induced pancreatic ductal dysfunction

Serum lipase in acute pancreatitis associated with hypertriglyceridaemia

Acute pancreatitis in childhood – a comparative international study and tale of two cities

Prognostic significance of organ failure and infected pancreatic necrosis in acute pancreatitis: An updated systematic review and meta‐analysis

The risk of recurrent pancreatitis after first episode of acute pancreatitis in relation to etiology and severity of disease: A systematic review, meta‐analysis and meta‐regression analysis

Evaluation of red blood cell distribution width, neutrophil‐to‐lymphocyte ratio, and other hematologic parameters in canine acute pancreatitis

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