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Impact of the grasping test on women’s cardiovascular systems, and the possibility of replacing the orthostatic tolerance test with it

Karolina Zaluska, Tomasz Sawicki, Bartlomiej Kulesza, Adam Nogalski

Current Issues in Pharmacy and Medical Sciences > 2014 > 27 > 4 > 217-219

The aim of this study was to test the impact of the Grasping Test (GT) on the female cardiovascular system and to ascertain the possibility of using this to replace the Orthostatic Tolerance Test (OT). In this study, 15 volunteer female students were examined, and their physiological parameters - their systolic (SBP) and diastolic blood pressures (DBP), and their heart rates (HR) - were compared....

article

Functional and morphometric differences between the early and delayed use of phototherapy in crushed median nerves of rats

Ana Paula Santos, Carla Adelino Suaid, Murilo Xavier, Fernanda Yamane

Lasers in Medical Science > 2012 > 27 > 2 > 479-486

This study evaluated the functional and quantitative differences between the early and delayed use of phototherapy in crushed median nerves. After a crush injury, low-level laser therapy (GaAs) was applied transcutaneously at the injury site, 3 min daily, with a frequency of five treatments per week for 2 weeks. In the early group, the first laser treatment started immediately after surgery, and in...

article

Mesenchymal stem cells in a polycaprolactone conduit enhance median-nerve regeneration, prevent decrease of creatine phosphokinase levels in muscle, and improve functional recovery in mice

J.T. Oliveira, F.M. Almeida, A. Biancalana, A.F. Baptista, more

Neuroscience > 2010 > 170 > 4 > 1295-1303

Although the majority of peripheral-nerve regeneration studies are carried out on the sciatic nerve, lesions of the upper extremities are more common in humans and usually lead to significant physical disabilities. The present study was driven by the hypothesis that a combination of strategies, namely grafts of mesenchymal stem cells (MSC) and resorbable polycaprolactone (PCL) conduits would improve...

article

Standardized crush injury of the mouse median nerve

G. Ronchi, S. Raimondo, A.S.P. Varejão, P. Tos, more

Journal of Neuroscience Methods > 2010 > 188 > 1 > 71-75

The employment of transgenic mouse models for peripheral nerve regeneration studies is continuously increasing. In this paper, we describe a standardized method for inducing a crush lesion in mouse median nerve using a non-serrated clamp exerting a crush compression force of 20.43MPa for a duration of 30s. Quantitative assessment of posttraumatic functional recovery by grasping test showed that recovery...

article

Functional and morphological assessment of a standardized crush injury of the rat median nerve

G. Ronchi, S. Nicolino, S. Raimondo, P. Tos, more

Journal of Neuroscience Methods > 2009 > 179 > 1 > 51-57

The availability of effective experimental models for investigating nerve regeneration and designing new strategies for promoting this unique repair process is important. The aim of this study was to standardize a rat median nerve crush injury model using a non-serrated clamp exerting a compression force of 17.02MPa for a duration of 30s. Results showed that functional recovery, evaluated by grasping...

article

Employment of the mouse median nerve model for the experimental assessment of peripheral nerve regeneration

P. Tos, G. Ronchi, S. Nicolino, C. Audisio, more

Journal of Neuroscience Methods > 2008 > 169 > 1 > 119-127

The experimental investigation of nerve regeneration after microsurgical repair is usually carried out in rats, rather than mice, because of the larger sized peripheral nerves. Today however, the availability of genetically modified mice makes the use of this laboratory animal very intriguing for investigating nerve regeneration at a molecular level. In this study we aimed to provide a standardization...

article

Functional recovery improvement is related to aberrant reinnervation trimming. A comparative study using fresh or predegenerated nerve grafts

Jayme Augusto Bertelli, Madjid Taleb, Jean Claude Mira, Marcos Flávio Ghizoni

Acta Neuropathologica > 2006 > 111 > 6 > 601-609

Experimentally predegenerated nerve grafts have been demonstrated to improve recovery. In a 12 month-long study, we compared the degree of recovery of conventional and predegenerated grafts in rat median nerve repair. To induce predegeneration the ulnar donor nerve was crushed and grafting to the median nerve was performed 2 weeks later. The day of recovery and the improvement of finger flexion strength...

article

On the use of the grasping test in the rat median nerve model: a re-appraisal of its efficacy for quantitative assessment of motor function recovery

Igor Papalia, Pierluigi Tos, Francesco Stagno d'Alcontres, Bruno Battiston, more

Journal of Neuroscience Methods > 2003 > 127 > 1 > 43 - 47

The quantitative assessment of motor function is an important requirement for studies on peripheral nerve injury and repair. So far, most studies on peripheral nerves have been performed on the sciatic nerve model using walking track analysis for assessing motor function. Alternatively, the employment of the median nerve model, which allows motor function evaluation by means of a simple behavioural...

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Search results

Impact of the grasping test on women’s cardiovascular systems, and the possibility of replacing the orthostatic tolerance test with it

Functional and morphometric differences between the early and delayed use of phototherapy in crushed median nerves of rats

Mesenchymal stem cells in a polycaprolactone conduit enhance median-nerve regeneration, prevent decrease of creatine phosphokinase levels in muscle, and improve functional recovery in mice

Standardized crush injury of the mouse median nerve

Functional and morphological assessment of a standardized crush injury of the rat median nerve

Employment of the mouse median nerve model for the experimental assessment of peripheral nerve regeneration

Functional recovery improvement is related to aberrant reinnervation trimming. A comparative study using fresh or predegenerated nerve grafts

On the use of the grasping test in the rat median nerve model: a re-appraisal of its efficacy for quantitative assessment of motor function recovery

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