Search results

article

A model explaining and predicting lamb flavour from the aroma-active chemical compounds released upon grilling light lamb loins

Mónica Bueno, M. Mar Campo, Juan Cacho, Vicente Ferreira, more

Meat Science > 2014 > 98 > 4 > 622-628

The objective of the work is to understand the role of the different aroma compounds in the perception of the local ''lamb flavour'' concept. For this, a set of 70 loins (Longissimus dorsi) from approximately seventy day-old Rasa Aragonesa male lambs were grilled and the aroma-active chemicals released during the grilling process were trapped and analyzed. Carbonyl compounds were derivatizated and...

article

Development of Iron‐Based Single Atom Materials for General and Efficient Synthesis of Amines

Zhuang Ma, Chakreshwara Kuloor, Carsten Kreyenschulte, Stephan Bartling, more

Angewandte Chemie > 136 > 37 > n/a - n/a

Earth abundant metal‐based heterogeneous catalysts with highly active and at the same time stable isolated metal sites constitute a key factor for the advancement of sustainable and cost‐effective chemical synthesis. In particular, the development of more practical, and durable iron‐based materials is of central interest for organic synthesis, especially for the preparation of chemical products related...

article

Development of Iron‐Based Single Atom Materials for General and Efficient Synthesis of Amines

Zhuang Ma, Chakreshwara Kuloor, Carsten Kreyenschulte, Stephan Bartling, more

Angewandte Chemie International Edition > 63 > 37 > n/a - n/a

Earth abundant metal‐based heterogeneous catalysts with highly active and at the same time stable isolated metal sites constitute a key factor for the advancement of sustainable and cost‐effective chemical synthesis. In particular, the development of more practical, and durable iron‐based materials is of central interest for organic synthesis, especially for the preparation of chemical products related...

article

g‐C₃N₄ Photocatalyzed Decarboxylative Oxidation of Carboxylic Acids and the Oxidation of Alkenes and Alkanes

Sangita Bishi, Bhabani Sankar Lenka, Peter Kreitmeier, Oliver Reiser, more

Advanced Synthesis & Catalysis > 366 > 15 > 3397 - 3403

The decarboxylative oxygenation of readily available carboxylic acids as well as the oxidation of alkenes and alkanes has been accomplished through visible light using g‐C₃N₄ as a robust and recyclable catalyst. The scalable protocol furnishes an array of aldehydes and ketones under mild reaction conditions, requiring only molecular oxygen as an oxidant. Notably, no addition of stochiometric amounts...

article

Electrochemical Synthesis of C(sp³)‐Rich Amines by Aminative Carbofunctionalization of Carbonyl Compounds

Wen‐Qiang Liu, Boon Chong Lee, NingXi Song, Zhenghao He, more

Angewandte Chemie > 136 > 26 > n/a - n/a

Alkylamines form the backbone of countless nitrogen‐containing small molecules possessing desirable biological properties. Despite advances in amine synthesis through transition metal catalysis and photoredox chemistry, multicomponent reactions that leverage inexpensive materials to transform abundant chemical feedstocks into three‐dimensional α‐substituted alkylamines bearing complex substitution...

article

Electrochemical Synthesis of C(sp³)‐Rich Amines by Aminative Carbofunctionalization of Carbonyl Compounds

Wen‐Qiang Liu, Boon Chong Lee, NingXi Song, Zhenghao He, more

Angewandte Chemie International Edition > 63 > 26 > n/a - n/a

Alkylamines form the backbone of countless nitrogen‐containing small molecules possessing desirable biological properties. Despite advances in amine synthesis through transition metal catalysis and photoredox chemistry, multicomponent reactions that leverage inexpensive materials to transform abundant chemical feedstocks into three‐dimensional α‐substituted alkylamines bearing complex substitution...

article

Rhodium(I) Catalyzed Hydroacylation Reactions of Alkenyl Compounds

Jun Zhao, Yuan‐Yi Lu, Rui Wang, Patience Peters, more

Advanced Synthesis & Catalysis > 366 > 8 > 1707 - 1718

Transition‐metal‐catalyzed hydroacylation of unsaturated substrates with aldehydes involving the formyl C(sp²)−H bond activation provides an expedient and efficient access to the carbonyl compounds such as ketones and esters, which are a class of important scaffolds in natural products and in drug development. Recently, extensive attention has been paid to the hydroacylation reactions of the components...

article

Bioinspired Functionalization of Carbonyl Compounds Enabled by Metal Chelated Bifunctional Ligands

Aniket Gupta, Ajijur Rahaman, Sukalyan Bhadra

Chemistry – A European Journal > 30 > 1 > n/a - n/a

In Nature, enzymatic reactions proceed through exceptionally ordered transition states giving rise to extraordinary levels of stereoselection. In those reactions, the active site of the enzyme plays crucial roles – through one position, it holds the substrate in the proximity to the reaction epicentre that facilitates both the reactivity and stereoselectivity of the chemical process. Inspired by this...

article

Wykorzystanie detekcji wychwytu elektronów do badania migracji związków karbonylowych z naczyń ekologicznych do żywności

Karolina Brończyk, Agata Dąbrowska, Adam Dąbrowski

Elektronika : konstrukcje, technologie, zastosowania > 2023 > Vol. 64, Nr 10 > 24--28

Przedstawione badania dotyczą migracji związków karbonylowych z naczyń ekologicznych do płynu modelowego A (woda destylowa na) oraz B (zakwaszona woda destylowana) pod wpływem różnych czynników czasowych i temperaturowych. Porównano oznaczone stężenia kancerogennego formaldehydu z ustalonym limitem mi gracji specyficznej (SML) dla tego związku. Dodatkowo zbadano wpływ naczyń ekologicznych na zmianę...

article

Metal‐ and Additive‐Free Electrochemical Oxidation of Benzylic C−X Bonds to Carbonyl Groups

Chengbo Sun, Boao Li, Xichao Peng, Ling Lin, more

European Journal of Organic Chemistry > 26 > 34 > n/a - n/a

A scalable electrochemical strategy for oxidation of various benzylic C−X bonds to carbonyl groups was achieved. The protocol runs under mild reaction conditions and air atmosphere in a simple undivided electrolysis cell, H₂O as oxygen source, and cheap graphite plates as both anode and cathode. In addition, the electrolysis strategy features good functional groups tolerance for selectively generating...

article

Regioselective Formal β‐Allylation of Carbonyl Compounds Enabled by Cooperative Nickel and Photoredox Catalysis

Kun Liu, Zhe Wang, Augustinus N. Künzel, Marcus Layh, more

Angewandte Chemie International Edition > 62 > 37 > n/a - n/a

The Tsuji–Trost reaction between carbonyl compounds and allylic precursors has been widely used in the synthesis of natural products and pharmaceutical compounds. As the α‐C−H bond is far more acidic than the β‐C−H bond, carbonyl compounds undergo highly regioselective allylation at the α‐position and their β‐allylation is therefore highly challenging. This innate α‐reactivity conversely hampers diversity,...

article

Regioselective Formal β‐Allylation of Carbonyl Compounds Enabled by Cooperative Nickel and Photoredox Catalysis

Kun Liu, Zhe Wang, Augustinus N. Künzel, Marcus Layh, more

Angewandte Chemie > 135 > 37 > n/a - n/a

The Tsuji–Trost reaction between carbonyl compounds and allylic precursors has been widely used in the synthesis of natural products and pharmaceutical compounds. As the α‐C−H bond is far more acidic than the β‐C−H bond, carbonyl compounds undergo highly regioselective allylation at the α‐position and their β‐allylation is therefore highly challenging. This innate α‐reactivity conversely hampers diversity,...

article

Photocatalyzed Direct α‐Alkylation of Esters Using Styrenes

Pengzhi Wang, Anna V. Bay, Emelia J. Farnam, Karl A. Scheidt

Advanced Synthesis & Catalysis > 365 > 14 > 2361 - 2366

A mild photocatalyzed approach to achieve the α‐alkylation of esters via formation of an α ‐radical is disclosed here. Cesium enolates of esters were generated in situ using Cs₂CO₃ as a base. A subsequent photocatalyzed oxidation at the α‐carbon of these enolates produced an α‐radical that was added into activated alkenes. This is the first example accessing the α‐carbon radical of esters in photoredox...

article

Alkali Chloride Adducts of Acyclic Acylaluminum: Synthesis, Structure, and Reactivity Studies

Genfeng Feng, Makoto Yamashita

Angewandte Chemie > 135 > 30 > n/a - n/a

Two acyclic acylaluminums and one cyclic acylaluminum dimer were synthesized by reaction of the recently reported Al‐anion with acyl chloride. The reaction of the acylaluminums with TMSOTf and DMAP gave a ring‐expanded iminium‐substituted aluminate and a 2‐C−H cleaved product. In the reaction of acylaluminums toward C=O and C=N bonds, acyclic acylaluminums reacted as an acyl nucleophile, while the...

article

Alkali Chloride Adducts of Acyclic Acylaluminum: Synthesis, Structure, and Reactivity Studies

Genfeng Feng, Makoto Yamashita

Angewandte Chemie International Edition > 62 > 30 > n/a - n/a

Two acyclic acylaluminums and one cyclic acylaluminum dimer were synthesized by reaction of the recently reported Al‐anion with acyl chloride. The reaction of the acylaluminums with TMSOTf and DMAP gave a ring‐expanded iminium‐substituted aluminate and a 2‐C−H cleaved product. In the reaction of acylaluminums toward C=O and C=N bonds, acyclic acylaluminums reacted as an acyl nucleophile, while the...

article

α‐Benzylation of Carbonyl Compounds Enabled by Synergistic Copper/Amine Catalyzed Decarboxylation of Arylacetic Acids

Kangmei Wen, Mengxia Feng, Qiwen Gao, Chen Chen, more

Advanced Synthesis & Catalysis > 365 > 8 > 1140 - 1146

Herein, we report synergistic copper/amine‐catalyzed reactions for directly α‐benzylating carbonyl compounds with arylacetic acids. These reactions represent the first examples of decarboxylative oxidative synergistic transition‐metal/enamine catalysis for α‐functionalizing carbonyl compounds. The process features starting‐material availability, good functional group tolerance, mild reaction conditions,...

article

Front Cover: Photocatalytic Synthesis of Acetals and Ketals from Aldehydes and Silylenolethers without the Use of Acids (Chem. Eur. J. 13/2023)

Desirée Steuernagel, Hans‐Achim Wagenknecht

Chemistry – A European Journal > 29 > 13 > n/a - n/a

The photoredox catalytic cycle with an electron‐deficient perylene bisimide (PBI) runs as long as green light is provided. The substrate silylenolethers and aldehydes enter the cycle, are oxidized to their radical cations and converted to acetals and ketals, which leave the cycle as products. Acid catalysts are not needed. Ketal and acetal groups protect the carbonyl compounds like helmets. More information...

article

Photocatalytic Synthesis of Acetals and Ketals from Aldehydes and Silylenolethers without the Use of Acids

Desirée Steuernagel, Hans‐Achim Wagenknecht

Chemistry – A European Journal > 29 > 13 > n/a - n/a

Acetals and ketals are among the most important protecting groups for carbonyl compounds. A new method for acetalization and ketalization by means of photoredox catalysis has been developed. A biscyanolated perylene bisimide is used as an electron‐poor photocatalyst, together with green light (525 nm LED). Silylenolethers derived from aldehydes react efficiently to give acetals in good to excellent...

article

Cover Feature: α‐Amination of Carbonyl Compounds by Using Hypervalent Iodine‐Based Aminating Reagents Containing a Transferable (Diarylmethylene)amino Group (Chem. Eur. J. 10/2023)

Daichi Okumatsu, Kazuki Kawanaka, Shunpei Kainuma, Kensuke Kiyokawa, more

Chemistry – A European Journal > 29 > 10 > n/a - n/a

Hypervalent iodine‐based aminating reagents containing a transferable (diarylmethylene)amino group can be used for the α‐amination of simple carbonyl compounds such as esters, amides, and ketones in the presence of a lithium base. A snapshot of the unique coupling of an α‐carbonyl radical with an iminyl radical in this amination is given by the motif of spacecraft docking with a space station. More...

article

α‐Amination of Carbonyl Compounds by Using Hypervalent Iodine‐Based Aminating Reagents Containing a Transferable (Diarylmethylene)amino Group

Daichi Okumatsu, Kazuki Kawanaka, Shunpei Kainuma, Kensuke Kiyokawa, more

Chemistry – A European Journal > 29 > 10 > n/a - n/a

Hypervalent iodine‐based aminating reagents containing a transferable (diarylmethylene)amino group can be used for the α‐amination of simple carbonyl compounds such as esters, amides, and ketones in the presence of a lithium base. The (diarylmethylene)amino groups of the products can be readily modified, thus providing access to primary amines and diarylmethylamines. The developed method features...

INFONA - science communication portal

Search results

A model explaining and predicting lamb flavour from the aroma-active chemical compounds released upon grilling light lamb loins

Development of Iron‐Based Single Atom Materials for General and Efficient Synthesis of Amines

Development of Iron‐Based Single Atom Materials for General and Efficient Synthesis of Amines

g‐C₃N₄ Photocatalyzed Decarboxylative Oxidation of Carboxylic Acids and the Oxidation of Alkenes and Alkanes

Electrochemical Synthesis of C(sp³)‐Rich Amines by Aminative Carbofunctionalization of Carbonyl Compounds

Electrochemical Synthesis of C(sp³)‐Rich Amines by Aminative Carbofunctionalization of Carbonyl Compounds

Rhodium(I) Catalyzed Hydroacylation Reactions of Alkenyl Compounds

Bioinspired Functionalization of Carbonyl Compounds Enabled by Metal Chelated Bifunctional Ligands

Wykorzystanie detekcji wychwytu elektronów do badania migracji związków karbonylowych z naczyń ekologicznych do żywności

Metal‐ and Additive‐Free Electrochemical Oxidation of Benzylic C−X Bonds to Carbonyl Groups

Regioselective Formal β‐Allylation of Carbonyl Compounds Enabled by Cooperative Nickel and Photoredox Catalysis

Regioselective Formal β‐Allylation of Carbonyl Compounds Enabled by Cooperative Nickel and Photoredox Catalysis

Photocatalyzed Direct α‐Alkylation of Esters Using Styrenes

Alkali Chloride Adducts of Acyclic Acylaluminum: Synthesis, Structure, and Reactivity Studies

Alkali Chloride Adducts of Acyclic Acylaluminum: Synthesis, Structure, and Reactivity Studies

α‐Benzylation of Carbonyl Compounds Enabled by Synergistic Copper/Amine Catalyzed Decarboxylation of Arylacetic Acids

Front Cover: Photocatalytic Synthesis of Acetals and Ketals from Aldehydes and Silylenolethers without the Use of Acids (Chem. Eur. J. 13/2023)

Photocatalytic Synthesis of Acetals and Ketals from Aldehydes and Silylenolethers without the Use of Acids

Cover Feature: α‐Amination of Carbonyl Compounds by Using Hypervalent Iodine‐Based Aminating Reagents Containing a Transferable (Diarylmethylene)amino Group (Chem. Eur. J. 10/2023)

α‐Amination of Carbonyl Compounds by Using Hypervalent Iodine‐Based Aminating Reagents Containing a Transferable (Diarylmethylene)amino Group

Filter options

Publication date

Content availability

Publication type

Publication language

Keywords

Data set

INFONA - science communication portal

Search results

Add recipient

Sending message cancelled

Are you sure you want to cancel sending this message?

Send message

Filter options

Publication date

Date range setting

Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.

Content availability

Publication type

Publication language

Keywords

Data set

Reporting an error / abuse

Sending the report failed

Accessibility options