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Items from 1 to 20 out of 92 results

article

Multifunctional Biomedical Materials Derived from Biological Membranes

Yuemin Wang, Xinyuan Xu, Xingyu Chen, Jianshu Li

Advanced Materials > 34 > 46 > n/a - n/a

The delicate structure and fantastic functions of biological membranes are the successful evolutionary results of a long‐term natural selection process. Their excellent biocompatibility and biofunctionality are widely utilized to construct multifunctional biomedical materials mainly by directly camouflaging materials with single or mixed biological membranes, decorating or incorporating materials...

article

Omega‐3 PUFA profoundly affect neural, physiological, and behavioural competences – implications for systemic changes in trophic interactions

Matthias Pilecky, Libor Závorka, Michael T. Arts, Martin J. Kainz

Biological Reviews > 96 > 5 > 2127 - 2145

In recent decades, much conceptual thinking in trophic ecology has been guided by theories of nutrient limitation and the flow of elements, such as carbon and nitrogen, within and among ecosystems. More recently, ecologists have also turned their attention to examining the value of specific dietary nutrients, in particular polyunsaturated fatty acids (PUFA), among which the omega‐3 PUFA, especially...

article

Membrane Creation in Polarizationless P Systems with Active Membranes

David Orellana-Martín, Luis Valencia-Cabrera, Agustín Riscos-Núñez, Mario J. Pérez-Jiménez

Fundamenta Informaticae > 2020 > Vol. 171, nr 1-4 > 297--311

Biological membranes play an active role in the evolution of cells over time. In the framework of Membrane Computing, P systems with active membranes capture this idea, and the possibility to increase the number of membranes during a computation. Classically, it has been considered, by using division rules, inspired in the mitosis process. Initially, the membranes in these models are supposed to have...

article

DSC studies on the interaction of lipophilic cytarabine prodrugs with DMPC multilamellar vesicles

Jhon Fernando Berrio Escobar, Diana Margarita Marquez Fernandez, Cristiano Giordani, Francesco Castelli, more

Journal of Thermal Analysis and Calorimetry > 2019 > 138 > 4 > 2759-2767

Cytarabine (1-β-d-arabinofuranosylcytosine, Ara-C), a pyrimidine nucleoside analogue, is used for the treatment of both acute and chronic myeloblastic leukemias and non-Hodgkin lymphoma. It has a very short plasma half-life and a very low oral bioavailability. To overcome these disadvantages, much effort has been focused on the design of cytarabine prodrugs. In this study, we have synthesized four...

article

Mathematical Description of the Diffusion Nature of Swelling and Shrinking of Erythrocytes at Radiation Injury

H. P. Sargsyan, A. H. Sargsyan, A. M. Danielyan

Journal of Contemporary Physics (Armenian Academy of Sciences) > 2019 > 54 > 3 > 326-332

The mathematical, formal-kinetic description of the diffusion nature of observed dimensional shifts in erythrocytes (the swelling and shrinkage) at early post-radiation period is proposed, and the quasi-chemical model of the diffusion diode is constructed for the transfer processes of micro-particles (including the water molecules) through biological membranes.

article

Imaging Proton Transport in Giant Vesicles through Cyclic Peptide–Polymer Conjugate Nanotube Transmembrane Ion Channels

Jason G. Binfield, Johannes C. Brendel, Neil R. Cameron, Ahmed M. Eissa, more

Macromolecular Rapid Communications > 39 > 19 > n/a - n/a

Since their discovery in 1993, interest in various aspects of cyclic peptides (CPs) has expanded rapidly. Of particular note is their potential to form artificial ion channels in lipid membranes, an attractive characteristic in supramolecular chemistry and biological research. The design and synthesis of cyclic peptide–polymer conjugates (CPPCs) that can self‐assemble within lipid bilayers into nanotubes,...

article

Hydrogel Membranes: Tough and Self‐Recoverable Thin Hydrogel Membranes for Biological Applications (Adv. Funct. Mater. 31/2018)

Ya Nan Ye, Martin Frauenlob, Lei Wang, Masumi Tsuda, more

Advanced Functional Materials > 28 > 31 > n/a - n/a

In article number 1801489, triblock copolymers are utilized in a non‐covalent double network strategy by Tasuku Nakajima, Jian Ping Gong, and co‐workers to yield 5–100 μm thin hydrogel membranes with ≈75% water content. Those semi‐permeable gel membranes are tough, fully self‐recoverable, and exhibit excellent biocompatibility and postoperative anti‐adhesive properties. This foreshadows their potential...

article

Tough and Self‐Recoverable Thin Hydrogel Membranes for Biological Applications

Ya Nan Ye, Martin Frauenlob, Lei Wang, Masumi Tsuda, more

Advanced Functional Materials > 28 > 31 > n/a - n/a

Tough and self‐recoverable hydrogel membranes with micrometer‐scale thickness are promising for biomedical applications, which, however, rarely be realized due to the intrinsic brittleness of hydrogels. In this work, for the first time, by combing noncovalent DN strategy and spin‐coating method, we successfully fabricated thin (thickness: 5–100 µm), yet tough (work of extension at fracture: 10⁵–10...

article

The Dynamic Behavior Possibilities of Raft-Like Domains in Biological Membranes

V. V. Ryazanov

Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology > 2018 > 12 > 2 > 160-169

A possible scenario of the behavior of a raft-like domain system oscillating near the phase transition point of the Verchulst transition type, when the form of the stationary distribution for the concentration of domains changes stepwise, has been considered. A stationary state of the system is also possible at the indicated phase transition point, as well as fluctuations in the state of the system...

article

Impact of external influences on characteristics of domains in biological membranes

V. V. Ryazanov

Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology > 2017 > 11 > 2 > 115-129

Living systems continually interact with the environment. External influences evoke complex processes in the entire system. In this work, the impact of external influences on the behavior of the domains in biological membranes is considered both in general and on special examples. A general approach of nonequilibrium statistical thermodynamics proposed by L.A. Stratonovich along with the same approach...

article

On the role of external force of actin filaments in the formation of tubular protrusions of closed membrane shapes with anisotropic membrane components

Luka Mesarec, Wojciech Góźdź, Samo Kralj, Miha Fošnarič, more

European Biophysics Journal > 2017 > 46 > 8 > 705-718

Biological membranes are composed of different components and there is no a priori reason to assume that all components are isotropic. It was previously shown that the anisotropic properties of membrane components may explain the stability of membrane tubular protrusions even without the application of external force. Our theoretical study focuses on the role of anisotropic membrane components in...

article

Lipid perturbation by membrane proteins and the lipophobic effect

Jean-Pierre Duneau, Jonathan Khao, James N. Sturgis

Biochimica et Biophysica Acta (BBA) - Biomembranes > 2017 > 1859 > 1 > 126-134

Understanding how membrane proteins interact with their environment is fundamental to the understanding of their structure, function and interactions. We have performed coarse-grained molecular dynamics simulations on a series of membrane proteins in a membrane environment to examine the perturbations of the lipids by the presence of protein. We analyze these perturbations in terms of elastic membrane...

article

Cholesterol oxidation products and their biological importance

Waldemar Kulig, Lukasz Cwiklik, Piotr Jurkiewicz, Tomasz Rog, more

Chemistry and Physics of Lipids > 2016 > 199 > C > 144-160

The main biological cause of oxysterols is the oxidation of cholesterol. They differ from cholesterol by the presence of additional polar groups that are typically hydroxyl, keto, hydroperoxy, epoxy, or carboxyl moieties. Under typical conditions, oxysterol concentration is maintained at a very low and precisely regulated level, with an excess of cholesterol. Like cholesterol, many oxysterols are...

article

Closed membrane shapes with attached BAR domains subject to external force of actin filaments

Luka Mesarec, Wojciech Góźdź, Veronika Kralj Iglič, Samo Kralj, more

Colloids and Surfaces B: Biointerfaces > 2016 > 141 > C > 132-140

Membrane deformations induced by attached BAR superfamily domains could trigger or facilitate the growth of plasma membrane protrusions. The BAR domain family consists of BAR, F-BAR and I-BAR domains, each enforcing a different local curvature when attached to the membrane surface. Our theoretical study mainly focuses on the role of I-BAR in the membrane tubular deformations generated or stabilised...

article

One-dimensional nonlinear elastodynamic models and their local conservation laws with applications to biological membranes

A.F. Cheviakov, J.-F. Ganghoffer

Journal of the Mechanical Behavior of Biomedical Materials > 2016 > 58 > C > 105-121

The framework of incompressible nonlinear hyperelasticity and viscoelasticity is applied to the derivation of one-dimensional models of nonlinear wave propagation in fiber-reinforced elastic solids. Equivalence transformations are used to simplify the resulting wave equations and to reduce the number of parameters. Local conservation laws and global conserved quantities of the models are systematically...

chapter

Adsorption of colloidal particles on mixed membranes

P. Schiller, M. Wahab, F. Bagusat, U. Reimer, more

Progress in Colloid and Polymer Science > Surface and Colloid Science > 143-145

The adsorption of polypeptides such as peripheral proteins disturbs the homogeneous distribution of the lipid components which form membranes. The lipid redistribution leads to an enhanced surface density of adsorbed polypeptides. For lipid mixtures with a tendency towards demixing this effect is more pronounced than for ideal mixtures. Then the adsorbate density strongly increases with increasing...

chapter

Adsorption of colloidal particles on mixed membranes

P. Schiller, M. Wahab, F. Bagusat, U. Reimer, more

Progress in Colloid and Polymer Science > Surface and Colloid Science > 143-145

article

Stochastic model of domain kinetics in biological membranes

V. V. Ryazanov

Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology > 2016 > 10 > 2 > 109-117

A stochastic storage model based on the behavior of macroscopic variables of the system is used to describe the kinetics of raft-like domains in biological membranes. For a simple output model, we examine the features of the system behavior corresponding to the noise-induced nonequilibrium phase transitions. Characteristics of the behavior of the statistical system are obtained: an explicit form of...

article

Continuous Modeling of Calcium Transport Through Biological Membranes

J. J. Jasielec, R. Filipek, K. Szyszkiewicz, T. Sokalski, more

Journal of Materials Engineering and Performance > 2016 > 25 > 8 > 3285-3290

In this work an approach to the modeling of the biological membranes where a membrane is treated as a continuous medium is presented. The Nernst-Planck-Poisson model including Poisson equation for electric potential is used to describe transport of ions in the mitochondrial membrane—the interface which joins mitochondrial matrix with cellular cytosis. The transport of calcium ions is considered. Concentration...

article

The orchestra of lipid-transfer proteins at the crossroads between metabolism and signaling

Antonella Chiapparino, Kenji Maeda, Denes Turei, Julio Saez-Rodriguez, more

Progress in Lipid Research > 2016 > 61 > C > 30-39

Within the eukaryotic cell, more than 1000 species of lipids define a series of membranes essential for cell function. Tightly controlled systems of lipid transport underlie the proper spatiotemporal distribution of membrane lipids, the coordination of spatially separated lipid metabolic pathways, and lipid signaling mediated by soluble proteins that may be localized some distance away from membranes...

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Search results

Multifunctional Biomedical Materials Derived from Biological Membranes

Omega‐3 PUFA profoundly affect neural, physiological, and behavioural competences – implications for systemic changes in trophic interactions

Membrane Creation in Polarizationless P Systems with Active Membranes

DSC studies on the interaction of lipophilic cytarabine prodrugs with DMPC multilamellar vesicles

Mathematical Description of the Diffusion Nature of Swelling and Shrinking of Erythrocytes at Radiation Injury

Imaging Proton Transport in Giant Vesicles through Cyclic Peptide–Polymer Conjugate Nanotube Transmembrane Ion Channels

Hydrogel Membranes: Tough and Self‐Recoverable Thin Hydrogel Membranes for Biological Applications (Adv. Funct. Mater. 31/2018)

Tough and Self‐Recoverable Thin Hydrogel Membranes for Biological Applications

The Dynamic Behavior Possibilities of Raft-Like Domains in Biological Membranes

Impact of external influences on characteristics of domains in biological membranes

On the role of external force of actin filaments in the formation of tubular protrusions of closed membrane shapes with anisotropic membrane components

Lipid perturbation by membrane proteins and the lipophobic effect

Cholesterol oxidation products and their biological importance

Closed membrane shapes with attached BAR domains subject to external force of actin filaments

One-dimensional nonlinear elastodynamic models and their local conservation laws with applications to biological membranes

Adsorption of colloidal particles on mixed membranes

Adsorption of colloidal particles on mixed membranes

Stochastic model of domain kinetics in biological membranes

Continuous Modeling of Calcium Transport Through Biological Membranes

The orchestra of lipid-transfer proteins at the crossroads between metabolism and signaling

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