Background: After acute necrotizing pancreatitis (ANP), a pancreatic fistula may occur from disconnected pancreatic duct syndrome (DPDS) where a segment of the pancreas is no longer in continuity with the main pancreatic duct.
Aim: To study the outcome of patients treated using Roux‐Y pancreatic fistula tract‐jejunostomy for DPDS after ANP.
Methods: Between 2002 and 2011, patients treated for DPDS...
Acute pancreatitis is an inflammatory condition with a variable clinical course. Diagnosis is based upon clinical presentation, laboratory indices and imaging studies, whilst illness severity can be assessed by clinical scoring systems, such as the Ranson, Glasgow or APACHE II criteria, or by radiological assessments such as the CT severity index. Most patients develop self-limiting disease but a...
Primary angiosarcoma of the pancreas is an extremely rare neoplasm that often mimicks severe acute pancreatitis.A 58-year-old man was admitted with clinical and laboratory signs of severe acute pancreatitis. Contrast enhanced CT scan demonstrated haemorrhagic necrotizing inflammation of the pancreas involving the pancreatic tail, splenic hilum and small bowels with multiple peripancreatic and free...
Background and Aim
The study aims to determine and quantify the stratified risk of recurrent pancreatitis (RP) after the first episode of acute pancreatitis in relation to etiology and severity of disease.
A systematic review and meta‐analysis in compliance with PRISMA statement standards was conducted. A search of electronic information sources was conducted to identify all studies investigating...
To determine if RBC distribution width (RDW), neutrophil‐to‐lymphocyte ratio (NLR), and other hematological parameters are associated with increased odds of in‐hospital mortality, increased length of hospitalization (LOH), or disease severity as measured by the Canine Acute Pancreatitis Severity (CAPS) score in dogs with acute pancreatitis (AP).
Retrospective, multicenter study...
To analyse the clinical characteristics and risk factors for tigecycline‐induced pancreatitis (TIP) and evaluate the safety and efficiency of tigecycline use in non‐TIP.
A retrospective case‐control study was conducted on adult and juvenile patients administered tigecycline for >3 days. The adults were classified as TIP, non‐TIP (pancreatitis with other causes) and non‐pancreatitis...
We aimed to investigate the prevalence of acute pancreatitis (AP) and hyperenzymemia as well as their clinical impact on postoperative survival outcomes in patients with pancreatic neuroendocrine tumors (PNETs).
A retrospective cohort study of 218 patients who underwent radical surgical resection for nonfunctional PNETs (NF‐PNETs) was conducted. Multivariate survival analysis...
The Ranson score has 11 parameters that are complex and laborious to implement. In this study, we aimed to create a revised Ranson score by modifying the parameters in Ranson.
A total of 938 patients diagnosed with acute pancreatitis (AP) between 2014 and 2021 were included in the study. The parameters of the Ranson score were included in the univariate and multivariate analyses...
Background and Aims
In the Asian population, existing studies regarding the association between smoking and acute pancreatitis are few in number. The aim of this study was to investigate the incidence of acute pancreatitis according to smoking habits and smoking habit changes of the Korean population.
We used clinical data from individuals (aged 20 years or older) who received health examinations...
Hypertriglyceridemia (HTG) is a metabolic disorder, defined when serum or plasma triglyceride concentration (seTG) is >1.7 mM. HTG can be categorized as mild to very severe groups based on the seTG value. The risk of acute pancreatitis (AP), a serious disease with high mortality and without specific therapy, increases with the degree of HTG. Furthermore, even mild or moderate HTG aggravates AP...
Background and Purpose
Gut microbiota dysbiosis induced by acute pancreatitis (AP) exacerbates pancreatic injury and systemic inflammatory responses. The alleviation of gut microbiota dysbiosis through faecal microbiota transplantation (FMT) is considered a potential strategy to reduce tissue damage and inflammation in many clinical disorders. Here, we aim to investigate the effect of gut microbiota...
The treatment of acute pancreatitis (AP) induced by hypertriglyceridemia (HTG) remains controversial with regard to plasmapheresis vs conventional treatment. We reviewed relevant articles to explore the efficacy of plasmapheresis in the management of HTG‐induced AP.
We systematically reviewed studies that compared plasmapheresis with conventional treatment for HTG‐induced AP...
Acute pancreatitis (AP) is a frequently encountered adverse drug reaction. However, the validity of diagnostic codes for AP is unknown. We aimed to determine the positive predictive value (PPV) of a diagnostic code‐based algorithm for identifying patients with AP within the US Veterans Health Administration and evaluate the value of adding readily available structured laboratory information...
To evaluate the usefulness of routinely measured biochemical and complete blood count parameters as potential markers of the severity of paediatric acute pancreatitis (AP).
The retrospective study included children with AP hospitalised over a 3 years period. Demographic, clinical and laboratory data were collected.
In total, 55 patients were enrolled in the study. Mild AP...
There is no evidence regarding the optimal balloon dilation time during endoscopic papillary large balloon dilation (EPLBD). The study aim was to evaluate the efficacy of 2‐minute extended balloon dilation for EPLBD.
Two hundred and five patients who underwent EPLBD during endoscopic retrograde cholangiopancreatography (ERCP) for bile duct stones at three tertiary centers...
Circular RNAs (circRNAs) have been found to be involved in the progression of acute pancreatitis (AP). The objective of our study was to investigate the effects of circ_0000284 on caerulein‐induced AR42J cell injury. To mimic AP in vitro, rat pancreatic acinar AR42J cells were treated with caerulein. The expression of circ_0000284 and miR‐10a‐5p was evaluated by quantitative real‐time polymerase chain...
After treatment of walled‐off necrosis, a pigtail plastic stent was placed in the fistula to prevent recurrence. Two years later, barium used in routine upper gastrointestinal radiography leaked into the residual cavity of the walled‐off necrosis. Tonozuka and colleagues conclude that an indwelling pigtail plastic stent provides long‐term drainage, but requires precautions.
Outcome of severe acute pancreatitis (SAP) highly depends on the degree of systemic inflammation and organ failure. Although treatment approaches targeting the inflammatory cascade have failed in pancreatitis, recent studies suggest that extracorporeal cytokine adsorption effectively reduces concentrations of pro‐inflammatory cytokines and potentially improves the outcome of sepsis.
Severe acute pancreatitis has a high mortality of 20%–40%, but there is a lack of optimal prognostic biomarker for the severity of acute pancreatitis (AP) or mortality. This study is designed to investigate the relationship between serum cholinesterase (ChE) level and poor outcomes of AP.
A total of 1904 AP patients were screened in the study, and we finally got 692 patients...
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