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article

Roux‐en‐Y drainage of a pancreatic fistula for disconnected pancreatic duct syndrome after acute necrotizing pancreatitis

Erik G. Pearson, Courtney L. Scaife, Sean J. Mulvihill, Robert E. Glasgow

HPB > 14 > 1 > 26 - 31

Background: After acute necrotizing pancreatitis (ANP), a pancreatic fistula may occur from disconnected pancreatic duct syndrome (DPDS) where a segment of the pancreas is no longer in continuity with the main pancreatic duct. Aim: To study the outcome of patients treated using Roux‐Y pancreatic fistula tract‐jejunostomy for DPDS after ANP. Methods: Between 2002 and 2011, patients treated for DPDS...

article

Acute pancreatitis

Deanne Bell, Margaret G. Keane, Stephen P. Pereira, D. Bell, more

Medicine > 2015 > 43 > 3 > 174-181

Acute pancreatitis is an inflammatory condition with a variable clinical course. Diagnosis is based upon clinical presentation, laboratory indices and imaging studies, whilst illness severity can be assessed by clinical scoring systems, such as the Ranson, Glasgow or APACHE II criteria, or by radiological assessments such as the CT severity index. Most patients develop self-limiting disease but a...

article

Primary angiosarcoma of the pancreas mimicking severe acute pancreatitis – Case report

Adrienn Csiszkó, István László, Károly Palatka, Károly Gábor Szabó, more

Pancreatology > 2015 > 15 > 1 > 84-87

Primary angiosarcoma of the pancreas is an extremely rare neoplasm that often mimicks severe acute pancreatitis.A 58-year-old man was admitted with clinical and laboratory signs of severe acute pancreatitis. Contrast enhanced CT scan demonstrated haemorrhagic necrotizing inflammation of the pancreas involving the pancreatic tail, splenic hilum and small bowels with multiple peripancreatic and free...

article

All-trans-retinoic acid induced acute pancreatitis: a single or multifactorial association?

Rodrigo Lopes da Silva

International Journal of Hematology > 2011 > 93 > 4 > 561-562

article

The risk of recurrent pancreatitis after first episode of acute pancreatitis in relation to etiology and severity of disease: A systematic review, meta‐analysis and meta‐regression analysis

Shahab Hajibandeh, Rebecca Jurdon, Emily Heaton, Shahin Hajibandeh, more

Journal of Gastroenterology and Hepatology > 38 > 10 > 1718 - 1733

Background and Aim The study aims to determine and quantify the stratified risk of recurrent pancreatitis (RP) after the first episode of acute pancreatitis in relation to etiology and severity of disease. Methods A systematic review and meta‐analysis in compliance with PRISMA statement standards was conducted. A search of electronic information sources was conducted to identify all studies investigating...

article

Evaluation of red blood cell distribution width, neutrophil‐to‐lymphocyte ratio, and other hematologic parameters in canine acute pancreatitis

Meghan M. Johnson, John C. Gicking, Deborah A. Keys

Journal of Veterinary Emergency and Critical Care > 33 > 5 > 587 - 597

Objective To determine if RBC distribution width (RDW), neutrophil‐to‐lymphocyte ratio (NLR), and other hematological parameters are associated with increased odds of in‐hospital mortality, increased length of hospitalization (LOH), or disease severity as measured by the Canine Acute Pancreatitis Severity (CAPS) score in dogs with acute pancreatitis (AP). Design Retrospective, multicenter study...

article

Clinical characteristics and risk factors for tigecycline‐induced pancreatitis in a tertiary hospital: A retrospective study

Qinghai Tan, Yu Zhang, Mei Liu, De'an Tian, more

British Journal of Clinical Pharmacology > 89 > 9 > 2788 - 2797

Aims To analyse the clinical characteristics and risk factors for tigecycline‐induced pancreatitis (TIP) and evaluate the safety and efficiency of tigecycline use in non‐TIP. Methods A retrospective case‐control study was conducted on adult and juvenile patients administered tigecycline for >3 days. The adults were classified as TIP, non‐TIP (pancreatitis with other causes) and non‐pancreatitis...

article

Preoperative acute pancreatitis and hyperenzymemia are associated with poor prognosis in patients with nonfunctional pancreatic neuroendocrine tumors

Haiyu Song, Qingquan Tan, Yuan Yuan, Xubao Liu, more

Journal of Surgical Oncology > 127 > 7 > 1135 - 1142

Background We aimed to investigate the prevalence of acute pancreatitis (AP) and hyperenzymemia as well as their clinical impact on postoperative survival outcomes in patients with pancreatic neuroendocrine tumors (PNETs). Methods A retrospective cohort study of 218 patients who underwent radical surgical resection for nonfunctional PNETs (NF‐PNETs) was conducted. Multivariate survival analysis...

article

Revisiting the Ranson score in acute pancreatitis: Is the drop in hematocrit a worrisome sign?

Fatih Acehan, Mesut Tez, Cagdas Kalkan, Meral Akdogan, more

Journal of Hepato‐Biliary‐Pancreatic Sciences > 30 > 3 > 315 - 324

Background The Ranson score has 11 parameters that are complex and laborious to implement. In this study, we aimed to create a revised Ranson score by modifying the parameters in Ranson. Methods A total of 938 patients diagnosed with acute pancreatitis (AP) between 2014 and 2021 were included in the study. The parameters of the Ranson score were included in the univariate and multivariate analyses...

article

The association between smoking, changes in smoking behavior, and acute pancreatitis: A population‐based cohort study in Korea

Jae Min Lee, Kyung Do Han, Sang Hyub Lee, Jin Myung Park, more

Journal of Gastroenterology and Hepatology > 38 > 3 > 451 - 459

Background and Aims In the Asian population, existing studies regarding the association between smoking and acute pancreatitis are few in number. The aim of this study was to investigate the incidence of acute pancreatitis according to smoking habits and smoking habit changes of the Korean population. Methods We used clinical data from individuals (aged 20 years or older) who received health examinations...

article

Mechanisms linking hypertriglyceridemia to acute pancreatitis

Lóránd Kiss, Gabriella Fűr, Sailaja Pisipati, Prasad Rajalingamgari, more

Acta Physiologica > 237 > 3 > n/a - n/a

Hypertriglyceridemia (HTG) is a metabolic disorder, defined when serum or plasma triglyceride concentration (seTG) is >1.7 mM. HTG can be categorized as mild to very severe groups based on the seTG value. The risk of acute pancreatitis (AP), a serious disease with high mortality and without specific therapy, increases with the degree of HTG. Furthermore, even mild or moderate HTG aggravates AP...

article

Gut microbiota‐derived nicotinamide mononucleotide alleviates acute pancreatitis by activating pancreatic SIRT3 signalling

Li‐Wei Liu, Yu Xie, Guan‐Qun Li, Tao Zhang, more

British Journal of Pharmacology > 180 > 5 > 647 - 666

Background and Purpose Gut microbiota dysbiosis induced by acute pancreatitis (AP) exacerbates pancreatic injury and systemic inflammatory responses. The alleviation of gut microbiota dysbiosis through faecal microbiota transplantation (FMT) is considered a potential strategy to reduce tissue damage and inflammation in many clinical disorders. Here, we aim to investigate the effect of gut microbiota...

article

Plasmapheresis compared with conventional treatment for hypertriglyceridemia‐induced acute pancreatitis: A systematic review and meta‐analysis

Li‐Hong Yan, Xin‐Hui Hu, Ruo‐Xin Chen, Ming‐Ming Pan, more

Journal of Clinical Apheresis > 38 > 1 > 4 - 15

Background The treatment of acute pancreatitis (AP) induced by hypertriglyceridemia (HTG) remains controversial with regard to plasmapheresis vs conventional treatment. We reviewed relevant articles to explore the efficacy of plasmapheresis in the management of HTG‐induced AP. Methods We systematically reviewed studies that compared plasmapheresis with conventional treatment for HTG‐induced AP...

article

Development and validation of case‐finding algorithms to identify acute pancreatitis in the Veterans Health Administration

Louise L. Wang, Jane Dobkin, Sanjay Salgado, David E. Kaplan, more

Pharmacoepidemiology and Drug Safety > 31 > 12 > 1294 - 1299

Purpose Acute pancreatitis (AP) is a frequently encountered adverse drug reaction. However, the validity of diagnostic codes for AP is unknown. We aimed to determine the positive predictive value (PPV) of a diagnostic code‐based algorithm for identifying patients with AP within the US Veterans Health Administration and evaluate the value of adding readily available structured laboratory information...

article

The course of acute pancreatitis in children and potential simple laboratory markers of severity – A single Centre retrospective study

Kamila Kwiatek‐Średzińska, Martyna Kiryłowska, Mirosława Uścinowicz, Urszula Daniluk, more

Acta Paediatrica > 111 > 11 > 2229 - 2234

Aim To evaluate the usefulness of routinely measured biochemical and complete blood count parameters as potential markers of the severity of paediatric acute pancreatitis (AP). Methods The retrospective study included children with AP hospitalised over a 3 years period. Demographic, clinical and laboratory data were collected. Results In total, 55 patients were enrolled in the study. Mild AP...

article

Efficacy of endoscopic large balloon dilation extended for 2 minutes in bile duct stone removal: A multicenter retrospective study

Kazunari Nakahara, Yosuke Michikawa, Keigo Suetani, Junya Sato, more

Journal of Hepato‐Biliary‐Pancreatic Sciences > 29 > 8 > 932 - 940

Background/Purpose There is no evidence regarding the optimal balloon dilation time during endoscopic papillary large balloon dilation (EPLBD). The study aim was to evaluate the efficacy of 2‐minute extended balloon dilation for EPLBD. Methods Two hundred and five patients who underwent EPLBD during endoscopic retrograde cholangiopancreatography (ERCP) for bile duct stones at three tertiary centers...

article

Circ_0000284 Promoted Acute Pancreatitis Progression through the Regulation of miR‐10a‐5p/Wnt/β‐Catenin Pathway

Huali Huang, Wenjing Chen, Jiefu Lu, Shiyu Zhang, more

Chemistry & Biodiversity > 19 > 6 > n/a - n/a

Circular RNAs (circRNAs) have been found to be involved in the progression of acute pancreatitis (AP). The objective of our study was to investigate the effects of circ_0000284 on caerulein‐induced AR42J cell injury. To mimic AP in vitro, rat pancreatic acinar AR42J cells were treated with caerulein. The expression of circ_0000284 and miR‐10a‐5p was evaluated by quantitative real‐time polymerase chain...

article

Long‐term precautions after endoscopic ultrasound‐guided transmural drainage for pancreatic fluid collection

Ryosuke Tonozuka, Shuntaro Mukai, Takao Itoi

Journal of Hepato‐Biliary‐Pancreatic Sciences > 29 > 5 > e39 - e40

Highlight After treatment of walled‐off necrosis, a pigtail plastic stent was placed in the fistula to prevent recurrence. Two years later, barium used in routine upper gastrointestinal radiography leaked into the residual cavity of the walled‐off necrosis. Tonozuka and colleagues conclude that an indwelling pigtail plastic stent provides long‐term drainage, but requires precautions.

article

Influence of extracorporeal cytokine adsorption on hemodynamics in severe acute pancreatitis: Results of the matched cohort pancreatitis cytosorbents inflammatory cytokine removal (PACIFIC) study

Sebastian Rasch, Sengül Sancak, Johanna Erber, Johannes Wießner, more

Artificial Organs > 46 > 6 > 1019 - 1026

Background Outcome of severe acute pancreatitis (SAP) highly depends on the degree of systemic inflammation and organ failure. Although treatment approaches targeting the inflammatory cascade have failed in pancreatitis, recent studies suggest that extracorporeal cytokine adsorption effectively reduces concentrations of pro‐inflammatory cytokines and potentially improves the outcome of sepsis. ...

article

Predictive value of serum cholinesterase in the mortality of acute pancreatitis: A retrospective cohort study

Mei Wei, Xiaochun Xie, Xianqiang Yu, Yingying Lu, more

European Journal of Clinical Investigation > 52 > 6 > n/a - n/a

Background Severe acute pancreatitis has a high mortality of 20%–40%, but there is a lack of optimal prognostic biomarker for the severity of acute pancreatitis (AP) or mortality. This study is designed to investigate the relationship between serum cholinesterase (ChE) level and poor outcomes of AP. Methods A total of 1904 AP patients were screened in the study, and we finally got 692 patients...

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ACUTE PANCREATITIS (1,518)
CHRONIC PANCREATITIS (78)
PANCREAS (53)
SEVERITY (53)
INFLAMMATION (50)
RAT (48)
PANCREATIC NECROSIS (45)
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L-ARGININE (14)
TREATMENT (14)
ERCP (13)
GUIDELINES (13)
OUTCOME (13)
PARENTERAL NUTRITION (13)
WALLED-OFF PANCREATIC NECROSIS (13)
GHRELIN (12)
LUNG INJURY (12)
MAGNETIC RESONANCE IMAGING (12)
NUTRITION (12)
PANCREATIC ACINAR CELLS (12)
PANCREATIC PSEUDOCYST (12)
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TNF-Α (10)
ACUTE LUNG INJURY (9)
CFTR (9)
CT (9)
ENDOSCOPY (9)
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LEPTIN (9)
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Search results

Roux‐en‐Y drainage of a pancreatic fistula for disconnected pancreatic duct syndrome after acute necrotizing pancreatitis

Acute pancreatitis

Primary angiosarcoma of the pancreas mimicking severe acute pancreatitis – Case report

All-trans-retinoic acid induced acute pancreatitis: a single or multifactorial association?

The risk of recurrent pancreatitis after first episode of acute pancreatitis in relation to etiology and severity of disease: A systematic review, meta‐analysis and meta‐regression analysis

Evaluation of red blood cell distribution width, neutrophil‐to‐lymphocyte ratio, and other hematologic parameters in canine acute pancreatitis

Clinical characteristics and risk factors for tigecycline‐induced pancreatitis in a tertiary hospital: A retrospective study

Preoperative acute pancreatitis and hyperenzymemia are associated with poor prognosis in patients with nonfunctional pancreatic neuroendocrine tumors

Revisiting the Ranson score in acute pancreatitis: Is the drop in hematocrit a worrisome sign?

The association between smoking, changes in smoking behavior, and acute pancreatitis: A population‐based cohort study in Korea

Mechanisms linking hypertriglyceridemia to acute pancreatitis

Gut microbiota‐derived nicotinamide mononucleotide alleviates acute pancreatitis by activating pancreatic SIRT3 signalling

Plasmapheresis compared with conventional treatment for hypertriglyceridemia‐induced acute pancreatitis: A systematic review and meta‐analysis

Development and validation of case‐finding algorithms to identify acute pancreatitis in the Veterans Health Administration

The course of acute pancreatitis in children and potential simple laboratory markers of severity – A single Centre retrospective study

Efficacy of endoscopic large balloon dilation extended for 2 minutes in bile duct stone removal: A multicenter retrospective study

Circ_0000284 Promoted Acute Pancreatitis Progression through the Regulation of miR‐10a‐5p/Wnt/β‐Catenin Pathway

Long‐term precautions after endoscopic ultrasound‐guided transmural drainage for pancreatic fluid collection

Influence of extracorporeal cytokine adsorption on hemodynamics in severe acute pancreatitis: Results of the matched cohort pancreatitis cytosorbents inflammatory cytokine removal (PACIFIC) study

Predictive value of serum cholinesterase in the mortality of acute pancreatitis: A retrospective cohort study

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