Search results

Items from 121 to 140 out of 2,299,245 results

1 ...
4
5
6
7
8
9
10

article

A Hybrid Supramolecular Polymeric Nanomedicine for Cascade‐Amplified Synergetic Cancer Therapy

Kai Yang, Shaolong Qi, Xinyang Yu, Bing Bai, more

Angewandte Chemie > 134 > 27 > n/a - n/a

Supramolecular nanomedicines have shown great merits in cancer therapy, but their clinical translation is hampered by monotonous therapeutic modality and unsatisfactory antitumor performance. Herein, a hybrid supramolecular polymeric nanomedicine (SNPs) is developed based on β‐cyclodextrin/camptothecin (CPT) host−guest molecular recognition and iron‐carboxylate coordination. Iron ions stabilizing...

article

Inside Back Cover: Expeditious Access to Morphinans by Chemical Synthesis (Angew. Chem. Int. Ed. 27/2022)

Lorenzo V. White, Nan Hu, Yu‐Tao He, Martin G. Banwell, more

Angewandte Chemie International Edition > 61 > 27 > n/a - n/a

The morphinan alkaloids , especially codeine and morphine, are derived from the opium poppy and have been used for millennia for pain management. They remain vital medicines today, but climate change and geopolitical uncertainties threaten existing supply chains. In their Communication (e202203186), Martin G. Banwell, Ping Lan, and co‐workers detail by far the shortest synthesis of (−)‐codeine reported...

article

Triarylamine/Bithiophene Copolymer with Enhanced Quinoidal Character as Hole‐Transporting Material for Perovskite Solar Cells

Hao‐Sheng Lin, Takahiro Doba, Wataru Sato, Yutaka Matsuo, more

Angewandte Chemie International Edition > 61 > 27 > n/a - n/a

Polytriarylamine is a popular hole‐transporting materials (HTMs) despite its suboptimal conductivity and significant recombination at the interface in a solar cell setup. Having noted insufficient conjugation among the triarylamine units along the polymer backbone, we inserted a bithiophene unit between two triarylamine units through iron‐catalyzed C−H/C−H coupling of a triarylamine/thiophene monomer...

article

A Selenide Catalyst for the Activation of Alkenes through Se⋅⋅⋅π Bonding

Xinglong Yuan, Yao Wang

Angewandte Chemie > 134 > 27 > n/a - n/a

Chalcogen bonding catalysis with divalent chalcogenides required using heteroatoms as electron donors to give reactivity, while the activation of hydrocarbons such as alkenes by this concept remains an unresolved challenge. Herein, we discovered a powerful selenide catalyst that showed unprecedented capability in the activation of alkenes. The Se⋅⋅⋅π interactions were capable of catalyzing a broad...

article

Decorating Bacteria with Triple Immune Nanoactivators Generates Tumor‐Resident Living Immunotherapeutics

Juanjuan Li, Qing Xia, Haiyan Guo, Zhenzhen Fu, more

Angewandte Chemie > 134 > 27 > n/a - n/a

An approach of decorating bacteria with triple immune nanoactivators is reported to develop tumor‐resident living immunotherapeutics. Under cytocompatible conditions, tumor‐specific antigens and checkpoint blocking antibodies are simultaneously conjugated onto bacterial surface and then polydopamine nanoparticles are formed via in situ dopamine polymerization. In addition to serving as a linker, polydopamine...

article

Silver‐Templated γ‐Keggin Alkyltin‐Oxo Cluster: Electronic Structure and Optical Limiting Effect

Yu Zhu, Zirui Wang, Dejing Li, Yin‐Di Zhu, more

Angewandte Chemie > 134 > 27 > n/a - n/a

As one of the most representative polyoxometalate (POM) structures, Keggin clusters have attracted considerable attention. Nevertheless, the noble‐metal‐templated Keggin structure has not been reported to date. In this work, for the first time, a Ag atom was successfully incorporated to template the formation of a γ‐Keggin alkytin‐oxo cluster. Moreover, the central Ag atom has brought a significant...

article

Manganese‐Catalysed Deuterium Labelling of Anilines and Electron‐Rich (Hetero)Arenes

Florian Bourriquen, Nils Rockstroh, Stephan Bartling, Kathrin Junge, more

Angewandte Chemie > 134 > 27 > n/a - n/a

There is a constant need for deuterium‐labelled products for multiple applications in life sciences and beyond. Here, a new class of heterogeneous catalysts is reported for practical deuterium incorporation in anilines, phenols, and heterocyclic substrates. The optimal material can be conveniently synthesised and allows for high deuterium incorporation using deuterium oxide as isotope source. This...

article

Chirality of Perylene Diimides: Design Strategies and Applications

Jie Li, Pengyu Li, Mingyu Fan, Xian Zheng, more

Angewandte Chemie > 134 > 27 > n/a - n/a

Chirality is a particularly important concept in nature and exists at all length scales, ranging from the molecular level to the supramolecular level. Over the last two decades, various design strategies have been developed to construct chiral materials based on perylene diimides (PDIs) and to mimic the chiral assembly process in biological systems, but applications of these chiral aggregates are...

article

Miocene Crustal Anatexis of Paleozoic Orthogneiss in the Zhada Area, Western Himalaya

Han CHEN, Guyue HU, Lingsen ZENG, Xuhui YU, more

Acta Geologica Sinica ‐ English Edition > 96 > 3 > 954 - 971

Granitic gneiss (orthogneiss) and Himalayan leucogranite are widely distributed in the Himalayan orogen, but whether or not the granitic gneiss made a contribution to the Himalayan leucogranite remains unclear. In this study, we present the petrological, geochronological and geochemical results for orthogneisses and leucogranites from the Zhada area, Western Himalayas. Zhada orthogneiss is composed...

article

Enrichment Mechanism and Prospects of Deep Oil and Gas

Fang HAO

Acta Geologica Sinica ‐ English Edition > 96 > 3 > 742 - 756

With the deepening of oil and gas exploration, the importance of depth is increasingly highlighted. The risk of preservation of storage space in deep reservoirs is greater than that in shallow and medium layers. Deep layers mean older strata, more complex structural evolution and more complex hydrocarbon accumulation processes, and even adjustment and transformation of oil and gas reservoirs. This...

article

Discrete Element Modeling of a Subduction Zone with a Seafloor Irregularity and its Impact on the Seismic Cycle

Liqing JIAO, Chung‐Han CHAN, Luc SCHOLTÈS, Aurélia HUBERT‐FERRARI, more

Acta Geologica Sinica ‐ English Edition > 96 > 3 > 776 - 790

Seafloor irregularities influence rupture behavior along the subducting slab and in the overriding plate, thus affecting earthquake cycles. Whether seafloor irregularities increase the likelihood of large earthquakes in a subduction zone remains contested, partially due to focus put either on fault development or on rupture pattern. Here, we simulate a subducting slab with a seafloor irregularity...

article

Multisphere Tectonics of the Earth System

Jishun REN, Baogui NIU, Qinqin XU, Lei ZHAO, more

Acta Geologica Sinica ‐ English Edition > 96 > 3 > 727 - 741

The fundamental theoretical framework of the Multisphere Tectonics of the Earth System is as follows: (1) It intends to extend the geotectonic studies from the crustal and lithospheric tectonics to the multisphere tectonics of the Earth system as a whole. (2) The global dynamics driven by both the Earth system and the cosmic celestial system: solar energy, multispheric interactions of the Earth system...

article

A New Species of Septuconularia (Hexangulaconulariidae, Cnidaria) from Cambrian Stage 2, South China

Zuchen SONG, Junfeng GUO, Jian HAN, Heyo VAN ITEN, more

Acta Geologica Sinica ‐ English Edition > 96 > 3 > 757 - 765

Hexangulaconulariids, an extinct family of medusozoan small shelly fossils (SSFs), were a conspicuous component of early Cambrian, shallow marine platform communities in South China. Described herein is Septuconularia crassiformis sp. nov. from Bed 5 of the Yanjiahe Formation (Cambrian Stage 2) in the Three Gorges area of Hubei Province. The new species differs from the type and only other known species,...

article

Genesis of the Taishanmiao Au Deposit in the Ningshan–Zhenan Ore Field, South Qinling Orogen, China: Evidence from Geochemical, Geochronological and S‐Pb‐H‐O Isotopical Study

Zuoyu GAO, Yunhua LIU, Naiquan SUN, Yuntao LI, more

Acta Geologica Sinica ‐ English Edition > 96 > 3 > 993 - 1009

The Taishanmiao Au deposit is in the western part of the Ningshan–Zhenan ore field, in the South Qinling orogen. Based on geological and geochemical features, we propose that the Taishanmiao Au deposit is a magmatic‐hydrothermal type of deposit. All samples have high SiO₂, K₂O + Na₂O contents and differentiation index values, low CaO, MgO, P₂O₅, and TiO₂ contents, are enriched in high field‐strength...

article

Acta Geologica Sinica (English Edition) Calls for Submission of Review Papers

Acta Geologica Sinica ‐ English Edition > 96 > 3 > 1114 - 1114

article

Measuring thirst distress of patients in the intensive care unit

Marleen Flim, José Hofhuis, Peter Spronk, Tiny Jaarsma

Nursing in Critical Care > 27 > 4 > 576 - 582

Background Thirst is one of the most intense and distressing symptoms experienced by patients in the intensive care unit (ICU), and no validated measurement tools exist. Validating a thirst measurement tool for the ICU population could be a first step in gaining a better understanding of thirst in ICU patients and aid the development and implementation of strategies regarding the prevention and control...

article

What's the big IDEA? A novel framework to strategically build an integrated clinical academic career

Joseph C. Manning

Nursing in Critical Care > 27 > 4 > 480 - 482

article

Nursing care and prevalence of adverse events in prone position: Characteristics of mechanically ventilated patients with severe SARS‐CoV‐2 pulmonary infection

María Dolores Rodríguez‐Huerta, Ana Díez‐Fernández, María Jesús Rodríguez‐Alonso, María Robles‐González, more

Nursing in Critical Care > 27 > 4 > 493 - 500

Background Because of the coronavirus disease 2019 (COVID‐19) pandemic, the use of prone positioning has dramatically increased in the intensive care unit (ICU). Because this manoeuvre is related to several complications, it must be performed in a protocolized manner by the appropriate personnel. Aim To determine the prevalence of adverse events (AEs) in patients admitted to the ICU with a diagnosis...

article

Mechanistic modeling and simulation of a complex low and high loading elution behavior of a polypeptide in cation exchange chromatography

Jonas Koch, Daniel Scheps, Matthias Gunne, Oliver Boscheinen, more

Journal of Separation Science > 45 > 12 > 2008 - 2023

The mechanistic modeling of preparative liquid chromatography is still a challenging task. Nonideal thermodynamic conditions may require activity coefficients for the mechanistic description of preparative chromatography. In this work, a chromatographic cation exchange step with a polypeptide having a complex elution behavior in low and high loading situations is modeled. Model calibration in the...

article

Clinical grade lentiviral vector purification and quality control requirements

Ruina Shi, Shenghua Jia, Huwei Liu, Honggang Nie

Journal of Separation Science > 45 > 12 > 2093 - 2101

Lentiviral vectors have been proven to be a powerful tool in gene therapies that includes the ability to perform long‐term gene editing in both dividing and non‐dividing cells. In order to meet the rising demand for clinical‐grade lentiviral vectors for future clinical trials and requirements by regulatory agencies, new methods and technologies were developed, including the rapid optimization of production...

1 ...
4
5
6
7
8
9
10

Data set:
Wiley

Publication date

Last 3 months (46,630)
Last year (202,173)
Last 3 years (607,701)

Close

Date range setting

Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.

From:

To:
Set your own date range

Content availability

Available (2,285,057)
None (14,188)

Publication type

article (2,241,217)
book (58,028)

Publication language

English (2,283,457)
German (41,376)
Spanish (1,594)
Chinese (1,563)
French (1,253)
Italian (8)
Portuguese (3)
Guarani (2)
Afar (1)
Dutch (1)
Bhutani (1)
Japanese (1)
more

Keywords

CANCER (8,552)
CLIMATE CHANGE (8,044)
CHILDREN (7,985)
INFLAMMATION (7,480)
COVID‐19 (7,096)
EPIDEMIOLOGY (7,057)
NANOPARTICLES (6,452)
DEPRESSION (6,388)
OBESITY (6,257)
APOPTOSIS (6,237)
META‐ANALYSIS (5,912)
MECHANICAL PROPERTIES (5,775)
QUALITY OF LIFE (5,646)
OXIDATIVE STRESS (5,218)
PREGNANCY (5,087)
BREAST CANCER (5,055)
PROGNOSIS (4,866)
NURSING (4,863)
PALLADIUM (4,857)
SURVIVAL (4,553)
MORTALITY (4,536)
SELF‐ASSEMBLY (4,408)
MORPHOLOGY (4,215)
PROSTATE CANCER (4,119)
SYSTEMATIC REVIEW (4,074)
SYNTHETIC METHODS (4,056)
COPPER (4,001)
TREATMENT (3,918)
DENSITY FUNCTIONAL CALCULATIONS (3,910)
DIABETES (3,886)
MAGNETIC RESONANCE IMAGING (3,824)
COMPOSITES (3,781)
DIAGNOSIS (3,677)
PHARMACOKINETICS (3,677)
ANXIETY (3,614)
EDUCATION (3,539)
ELECTROCHEMISTRY (3,451)
CHINA (3,439)
MRI (3,356)
GRAPHENE (3,346)
DEVELOPMENT (3,318)
GENDER (3,318)
MENTAL HEALTH (3,292)
FLUORESCENCE (3,279)
STRESS (3,252)
ASTHMA (3,230)
PARKINSON'S DISEASE (3,219)
AGING (3,215)
RISK FACTORS (3,208)
DEMENTIA (3,135)
MIGRATION (3,053)
MASS SPECTROMETRY (3,035)
ADSORPTION (3,016)
STROKE (3,014)
GENE EXPRESSION (2,966)
FORENSIC SCIENCE (2,954)
ALCOHOL (2,945)
HORSE (2,936)
HOMOGENEOUS CATALYSIS (2,897)
ONCOLOGY (2,883)
GROWTH (2,852)
NATURAL PRODUCTS (2,850)
KINETICS (2,826)
GOLD (2,824)
ULTRASOUND (2,819)
SURGERY (2,818)
HETEROCYCLES (2,817)
OXIDATION (2,813)
HEPATOCELLULAR CARCINOMA (2,810)
ALZHEIMER'S DISEASE (2,798)
IMMUNOHISTOCHEMISTRY (2,776)
STABILITY (2,749)
BIOMARKER (2,742)
ATRIAL FIBRILLATION (2,737)
IRON (2,729)
PREVALENCE (2,721)
SUPRAMOLECULAR CHEMISTRY (2,713)
ASYMMETRIC CATALYSIS (2,707)
PAIN (2,684)
COLORECTAL CANCER (2,679)
TEMPERATURE (2,640)
ADOLESCENTS (2,631)
LUMINESCENCE (2,617)
CHEMOTHERAPY (2,614)
CHILD (2,562)
SCREENING (2,555)
TYPE 2 DIABETES (2,541)
PHOTOCATALYSIS (2,521)
MACHINE LEARNING (2,519)
EVOLUTION (2,509)
HIV (2,506)
NANOSTRUCTURES (2,500)
STRUCTURE ELUCIDATION (2,495)
EPILEPSY (2,479)
CRYSTAL STRUCTURE (2,453)
RUTHENIUM (2,440)
QUALITATIVE RESEARCH (2,419)
BIOMARKERS (2,402)
GENETICS (2,391)
BIODIVERSITY (2,380)
more

INFONA - science communication portal

Search results

A Hybrid Supramolecular Polymeric Nanomedicine for Cascade‐Amplified Synergetic Cancer Therapy

Inside Back Cover: Expeditious Access to Morphinans by Chemical Synthesis (Angew. Chem. Int. Ed. 27/2022)

Triarylamine/Bithiophene Copolymer with Enhanced Quinoidal Character as Hole‐Transporting Material for Perovskite Solar Cells

A Selenide Catalyst for the Activation of Alkenes through Se⋅⋅⋅π Bonding

Decorating Bacteria with Triple Immune Nanoactivators Generates Tumor‐Resident Living Immunotherapeutics

Silver‐Templated γ‐Keggin Alkyltin‐Oxo Cluster: Electronic Structure and Optical Limiting Effect

Manganese‐Catalysed Deuterium Labelling of Anilines and Electron‐Rich (Hetero)Arenes

Chirality of Perylene Diimides: Design Strategies and Applications

Miocene Crustal Anatexis of Paleozoic Orthogneiss in the Zhada Area, Western Himalaya

Enrichment Mechanism and Prospects of Deep Oil and Gas

Discrete Element Modeling of a Subduction Zone with a Seafloor Irregularity and its Impact on the Seismic Cycle

Multisphere Tectonics of the Earth System

A New Species of Septuconularia (Hexangulaconulariidae, Cnidaria) from Cambrian Stage 2, South China

Genesis of the Taishanmiao Au Deposit in the Ningshan–Zhenan Ore Field, South Qinling Orogen, China: Evidence from Geochemical, Geochronological and S‐Pb‐H‐O Isotopical Study

Acta Geologica Sinica (English Edition) Calls for Submission of Review Papers

Measuring thirst distress of patients in the intensive care unit

What's the big IDEA? A novel framework to strategically build an integrated clinical academic career

Nursing care and prevalence of adverse events in prone position: Characteristics of mechanically ventilated patients with severe SARS‐CoV‐2 pulmonary infection

Mechanistic modeling and simulation of a complex low and high loading elution behavior of a polypeptide in cation exchange chromatography

Clinical grade lentiviral vector purification and quality control requirements

Filter options

Publication date

Content availability

Publication type

Publication language

Keywords

INFONA - science communication portal

Search results

Add recipient

Sending message cancelled

Are you sure you want to cancel sending this message?

Send message

Filter options

Publication date

Date range setting

Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.

Content availability

Publication type

Publication language

Keywords

Reporting an error / abuse

Sending the report failed

Accessibility options