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Following epidemiological observations that suggested links between low vitamin D exposure and increased risk of prostate cancer, interest in clarifying a potential role of this steroid hormone in prostate cancer has grown. While the results have been mixed, epidemiologic studies have suggested that severe vitamin D deficiency may increase the risk of clinically important prostate cancer. Laboratory...
It is well known that UV exposure is essential for subcutaneous vitamin D synthesis, which is important in maintaining mineral and bone homeostasis. In this chapter, we discuss findings in recent epidemiologic, in vitro and in vivo studies that suggest vitamin D has an additional role, skin cancer prevention. With accumulating evidence on the neoplastic effects of vitamin D, studies on vitamin D analogs...
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