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Electrical creation of aqueous pathways across the skin's outer layer [stratum corneum (SC)] provides an approach to transdermal delivery of medium-size water-soluble compounds. However, nerve stimulation should be avoided. Here, we show that a microstructured electrode array can significantly confine the electric field to the nerve-free SC. The prototype electrode-reservoir device (ERD) contains...
The water content of stratum corneum (SC) has been reported to vary depending on the anatomical sites. Each anatomical site respectively have their own proper water content of SC which reflects the status of skin health. Also, this anatomical region can be divided into relatively wet and dry area according to the degree of the water content of SC. In this study, we tried to investigate time series...
The water content of stratum corneum (SC) has been reported to vary depending on the anatomical sites. Each anatomical site respectively have their own proper water content of SC which reflects the status of skin health. Also, this anatomical region can be divided into relatively wet and dry area according to the degree of the water content of SC. In this study, we tried to investigate time series...
Regular electrical impedance tomography (EIT) is based on the surface electrodes which results in long application times, long stabilization times, and high ESEI. Clinically relevant information in electrical impedance tomography is diluted by the electrical properties of stratum corneum. Eliminating stratum corneum would improve the signals from the tissue. In this paper, a new concept and possible...
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