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31P MRS magnetization transfer (31P‐MT) experiments allow the estimation of exchange rates of biochemical reactions, such as the creatine kinase equilibrium and adenosine triphosphate (ATP) synthesis. Although various 31P‐MT methods have been successfully used on isolated organs or animals, their application on humans in clinical scanners poses specific challenges. This study compared two major 31...
Frequency‐labeled exchange transfer is a promising MRI technique for labeling and detecting exchanging protons of low‐concentration solutes through the water signal. Early frequency‐labeled exchange studies have used off‐resonance excitation‐based labeling schemes that are well suited to study rapidly exchanging protons or molecules far from the water resonance (e.g., water in paramagnetic contrast...
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