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The causes for the sporadic form of Alzheimer's disease (AD) arestill poorly understood, except from the fact that age is animportant risk factor. The main component of the characteristicamyloid plaques in brains of AD patients are Aβ peptides,derivatives of the amyloid precursor protein APP. Oxidativestress may contribute to the aetiology of AD by dysregulation ofAPP metabolism. Overexpression of...
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