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Bisphenol A (BPA) is an environmental pollutant to which humans are universally exposed, evident as low BPA concentrations present in biological samples in the majority of individuals in developed countries. Although BPA is widely detected in blood, the main source of human exposure is through ingestion, as BPA is broadly used in the plastic industry and therefore present in food containers. In this...
The purpose of this article was to observe interaction between drug and cancer cell with fluorescence probes and molecular imaging technology. In order to study the effect of cell growth and apoptosis morphology of Human gastric adenocarcinoma SGC-7901 induced by n-butanol extract from Capparis spionosa L. (CSBE), laser scanning microscopy was employed to observe apoptosis imaging. In addition, the...
We use analogies between chemistry and subthreshold electronics to develop fast, scalable, digitally programmable hardware models of stochastic genetic networks. We also present experimental results from a prototype 0.18 ??m CMOS chip that was designed for rapid simulations of gene activation, transcription and translation.
Gene regulatory networks often occur at such small scales that their dynamics are controlled by individual molecular events. This discrete behavior causes significant quantities of intrinsic noise. In some cases, mechanisms exist in the system to repress this noise. With different parameters, the same mechanisms may amplify the noise. By examining the properties of how noise is transmitted through...
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