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The immune system can be the target of many chemicals, with potentially severe adverse effects on the host’s health. In the literature, carbamate (CM) pesticides have been implicated in the increasing prevalence of diseases associated with alterations of the immune response, such as hypersensitivity reactions, some autoimmune diseases and cancers. CMs may initiate, facilitate, or exacerbate pathological...
We have shown the fetal liver cell engraftments into multiple tissues of adult healthy mice, achieved without suppressing the animals’ immune systems. Fetal cells from the livers of male C57Bl/6J Black lineage mice at day 13 to 15 of gestation were injected intravenously into female adult CC57W/MY White mice. The grafting was evaluated by Y-chromosome-specific PCR, cytometric analysis of fluorescently...
Experimental data obtained so far suggest that an efficacious anti-parasitic vaccine must either be completely effective against infective stage of a parasite or it must induce multi-stage, multi-immune response. Recently developed technology of DNA vaccination appears to offer the best prospect for the development of multivalent vaccines that will effectively activate both the humoral and cell mediated...
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