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This study is focused on changes in the brain function throughout the adulthood in healthy men and women performing task switching (TS) in the visual modality. One hundred and forty healthy subjects aged 20 to 65 years (69 men) participated in the experiments. In the fMRI study, the subjects performed a test that required switching attention between two objectives (classifying figures according to...
Several investigations have suggested that the orbitofrontal cortex (OFC) may be particularly vulnerable to the effects of age-related changes. We recently reported behavioral data indicating greater age differences in orbitofrontal tasks when directly compared to tasks tapping dorsolateral prefrontal functions. The present study was designed to investigate the neural underpinnings of age differences...
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