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This study analysed the physical effects of Cichorium Pumilum (CP), as a natural photosensitizer (PS), and Protoporphyrin IX (PpIX), as a synthetic PS, encapsulated with silica nanoparticles (SiNPs) in photodynamic therapy. The optimum concentrations of CP and PpIX, needed to destroy Red Blood Cells (RBC), were determined and the efficacy of encapsulated CP and PpIX were compared with naked CP and...
L-ascorbic acid and sodium carboxymethylcellulose were taken as raw material to synthesize polymer material L-ascorbic acid cellulose ester which had antioxidation effect. Antioxidation effect of o benzylgalloyl microcrystalline cellulose ester was appraised in vitro. The results showed that all the different concentrations L-ascorbic acid cellulose ester significantly improved GSH-Px activity of...
Pyridostigmine is a reversible inhibitor of acetylcholinesterase (AChE). The objective of the present analysis was to characterise the population pharmacokinetics / pharmacodynamics (PK/PD) of pyridostigmine given as pyridostigmine bromide. Fifty healthy Chinese males received 7 doses of 30 mg of pyridostigmine bromide each every 8 hours orally. Plasma concentrations of pyridostigmine and red blood...
In this study, the physiological parameters such as extracellular (SAGM+CPD+residual plasma) Na+, K+, Cl-, pH, 2,3-DPG and ATP together with the Cole-Cole parameters were measured using erythrocyte suspensions from 51 male donors (31 donors form the training set and 20 donors are used for testing), on the 0th, 10th, 21st, 35 th and 42nd days of storage. Accordingly, electrical parameters were all...
In this study, the physiological parameters such as extracellular (SAGM+CPD+residual plasma) Na+, K+, Cl-, pH, 2,3-DPG and ATP together with the Cole-Cole parameters were measured using erythrocyte suspensions from 51 male donors (31 donors form the training set and 20 donors are used for testing), on the 0th, 10th, 21st, 35 th and 42nd days of storage. Accordingly, electrical parameters were all...
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