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ObjectivesLipid‐based nutrient supplements (LNSs) are increasingly used in HIV programmes in resource‐limited settings. However, the possible effects of LNSs on the plasma concentrations of antiretroviral drugs have not been assessed. Here, we aimed to assess the effects of LNSs on plasma efavirenz and nevirapine trough concentrations in Ethiopian adult HIV‐infected patients.
MethodsThe effects of...
ObjectiveThe aim of this study was to assess the incidence of hepatotoxicity in patients who had used nonnucleoside reverse transcriptase inhibitors (NNRTIs) for at least 3 years.
MethodsThe study group consisted of HIV‐infected patients under follow‐up at our clinic, who had continuously used an NNRTI‐containing regimen (efavirenz or nevirapine) for at least 3 years. Patients who had used protease...
ObjectivesDyslipidaemic effects of antiretrovirals (ARVs) may contribute to increased cardiovascular risk (CR) in HIV‐1‐infected patients. The ARTEN (atazanavir/ritonavir on a background of tenofovir and emtricitabine vs. nevirapine on the same background, in naïve HIV‐1‐infected patients) study compared prospectively ritonavir‐boosted atazanavir (ATZ/r) 300 mg/100 mg once daily (qd) with immediate...
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