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Environment, customs and health status in northwest minority areas have been studied. We found the critical factors to prevent cerebral infraction. First rough sets theory had been used to reduce the attributes, secondly association rules had been used, finally logistic regression model had been used. The model solved the shortcomings of too many rules that caused by attribute redundancy and reliability...
Complex diseases may be caused by interactions or combined effects between multiple genetic and environmental factors. One of the main limitations of testing for interaction between genetic loci in large whole genome studies is the high computational cost of performing such analyses. In this study a new methodology for interaction testing (commonly referred to in genetics as the epistatic effect)...
The number of people that develop Alzheimer's Disease (AD) is rapidly rising, while the initial diagnosis and care of AD patients typically falls on non-specialist and still taking up to 3-5 years before being referred to specialists. An urgent need thus exists to develop methods to extract accurate and robust biomarkers from low-cost and non intrusive modalities such as electroencephalograms (EEGs)...
It remains a challenge to identify the different types of dementia and separate these from various subtypes from the normal effects of ageing. In this paper the potential of parametric images from FDG-PET studies to aid the classification of dementia using data mining techniques was investigated. Scalar, joint, histogram and voxel-level features were used in the investigation with principal component...
Ten to fifteen percent of individual with the hereditary long-QT syndrome (LQTS) involving the human ether-a-go-go related gene (HERG) do not have an abnormal QT prolongation but are at risk of lethal arrhythmic event. We investigated the phenotypic T-wave morphology for the identification of patients with HERG mutations. The standard 12-lead ECGs from carrier and non-carrier LQT2 patients were digitized...
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