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Traditionally, the severity of chronic obstructive pulmonary disease (COPD) and effectiveness of interventions have been determined using measures of lung function. However, a relatively small reduction or change in lung function — such as those observed in mild to moderate COPD — may not always reflect the impact of the disease or intervention on patients’ physical and psychological well-being. This...
Clinical benefits have been shown to occur when using the long-acting β 2 -agonist formoterol 4.5μg for as-needed medication rather than terbutaline 500μg in patients with unstable asthma taking an inhaled corticosteroid. This study compared their effects on health-related quality of life and the relation with conventional clinical indices in the same population. 362 asthmatics were randomized...
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