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Bis 2018 gab es noch keine allgemein anerkannte spezifische Therapie für Patienten mit nichtfernmetastasiertem kastrationsresistenten Prostatakarzinom (nmCRPC/M0CRPC). Dies führte zu individuellen Therapieentscheidungen ohne fundierte Datengrundlage. In der folgenden Übersichtsarbeit geben wir einen Überblick über die unterschiedlichen Entitäten des nmCRPC und diskutieren neue Therapiemodalitäten,...
Prostate cancer is one of the most common cancers diagnosed in men in the USA and 20–30% of men treated for localised prostate cancer will fail therapy and develop advanced prostate cancer. More drugs have been approved for the treatment of advanced prostate cancer in the past 3 years than in the past three decades, and each drug has its own mechanism of action and, often, unique monitoring requirements...
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