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A novel drug delivery device (DDD) with complex structures for providing linear drug release profiles was designed and fabricated directly from the CAD models using three-dimensional printing technique (3DP) systems. The DDDs were in donut shape and had local concentration variations of the release-retarding polymer in their three regions. Environmental scanning electron microscopy clearly showed...
Thermal and chemical stability of pentoxifylline from modified release tablets were studied. This experimental study observed the influence of temperature and humidity on the stability of pentoxifylline from the proposed formulations. The paper describes the HPLC determination of pentoxifylline from new controlled release tablets with hydrophilic matrix (HPMC, HPC, HEC). A C18 column with a mobile...
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