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Hyper-synchronous neural oscillations are the character of several neurological diseases such as epilepsy. On the other hand, glial cells and particularly astrocytes can influence neural synchronization. Therefore, based on the recent researches, a new bio-inspired stimulator is proposed which basically is a dynamical model of the astrocyte biophysical model. The performance of the new stimulator...
The substantia nigra pars reticulata (SNr) is a major output nucleus of the basal ganglia circuitry particularly sensitive to pathological dopamine depletion. Indeed, hyperactivity of SNr neurons is known to be responsible for some motor disorders characteristic of Parkinson's disease. The neuronal processing of basal ganglia dysfunction is well understood but, paradoxically, the role of astrocytes...
Pathophysiologic neural synchronization is a sign of several neurological disorders such as parkinson and epilepsy. In addition, based on established neurophysiologic findings, astrocytes (more type of glial cells) regulate dynamically the synaptic transmission and have key roles in stabilizing neural synchronization. Therefore, in the present study, a new model for digital astrocyte-inspired stimulator...
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