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Cell penetrating peptides (CPPs) are short peptides able to efficiently cross cellular membrane. The group includes great diversity of sequences and besides capability to enter various types of cells, their characteristic feature is lack of toxicity. CPPs can be divided according to their origin (natural and synthetic) or according to their physicochemical properties responsible for the cellpenetrating...
Transfers of cargoes into cells by means of carrier peptides are multi-steps biological phenomenon the mechanisms of which are unclear. We here discuss bases of realistic in silico molecular modeling approaches of the formation of non-covalent complexes considering CPPs and cargo diversities.
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