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An efficient and convenient copper‐mediated tandem C(sp2)‐H amination and annulation of arenes with 2‐aminopyridines to provide 11H‐pyrido[2,1‐b]quinazolin‐11‐ones has been developed. A variety of benzamides and 2‐aminopyridines bearing different substituents are compatible with this transformation
A novel tandem approach has been demonstrated for the direct synthesis of bioactive 3-aroylimidazo[1,2-a]pyridines from chalcones and 2-aminopyridines. The reported tandem reaction is atom-economical and expected to proceed via 1,4-Michael addition followed by copper catalyzed oxidative C–N bonding. Catalytic amount of copper was found to be crucial for the success of tandem reaction and it altered...
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