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Data reported until today suggested a pivotal role of nuclear DNA mutations in the process of carcinogenesis. Recently more and more authors claim that disruption of mitochondrial DNA should not be excluded from this analysis. mtDNA have been reported in many cancers of head and neck region. Mitochondrial D-loop has been proven to be mutation hot – spot with majority of mutations in the positions...
Oxidative stress, as a result of increased reactive oxygen species (ROS) production, is present in asthma. Glutathione peroxidase (GPx), a key antioxidative enzyme, inactivates ROS.of the study was to assess the activity of erythrocytes’ GPx in children with asthma.91 children were included in the study (36 female, 55 male) (mean age 9,41 yrs; SD = 3,12) with asthma diagnosed according to NHLBI/WHO...
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