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In the UK, the incidence of lung cancer is falling slowly. In 1999, there were 39,000 new registrations of lung cancer, second only to breast cancer. Because of its poor prognosis, it is the number one killer among cancers in the UK, and kills more females than breast cancer (about 13,000 per annum). The incidence is about 80 per 100,000 males and about 40 per 100,000 females. It is estimated that...
Lung cancer is the leading cause of cancer death in the industrialised world and is becoming a significant cause of mortality in developing countries. The vast majority of cases are a result of cigarette smoking. A number of genetic alterations are found in lung cancer, especially those effecting p53, a tumour suppressor gene that appears particularly sensitive to damage by tobacco carcinogens. Not...
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