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Background
Extracorporeal photopheresis (ECP) is one of the most widely used and effective cell‐based therapies for the treatment of T‐cell–mediated diseases. The patients' white blood cells (WBCs) are collected by apheresis and exposed to the photosensitizer 8‐methoxypsoralen (8‐MOP) and ultraviolet A (UVA) light before retransfusion. The UVA/8‐MOP combination has been in use in ECP for more than...
Background
United States healthcare spending continues to outpace other developed nations although efforts are being made to increase cost‐transparency. Recent legislation requires hospitals to publish a chargemaster, a list of all billable procedure codes together with prices. Chargemaster prices have been shown to be highly variable, if available, and are not typically paid, but contribute to negotiated...
Background
Extracorporeal photopheresis (ECP), an apheresis‐based therapy for various immunological diseases, works mainly by inducing apoptosis in lymphocytes. Several factors influence the efficacy of ECP with the photosensitizer 8‐methoxypsoralen (8‐MOP) and ultraviolet light A (UVA). This study aimed to optimize treatment by varying the 8‐MOP starting concentration and the cell suspension medium...
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