The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Conventional chemotherapy shows moderate efficiency against metastatic cancer since it targets only part of the mechanisms regulating tumor growth and metastasis. Here, gold nanorod (GNR)‐based host‐guest nanoplatforms loaded with docetaxel (DTX) and small interfering RNA (siRNA)‐p65 (referred to as DTX‐loaded GNR (GDTX)/p65) for chemo‐, RNA interference (RNAi), and photothermal ablation (PTA) cooperative...
A multifunctional nanoparticle based on gold nanorod (GNR), utilizing mRNA triggered chemo‐drug release and near‐infrared photoacoustic effect, is developed for a combined chemo‐photoacoustic therapy. The constructed nanoparticle (GNR‐DNA/FA:DOX) comprises three functional components: (i) GNR as the drug delivery platform and photoacoustic effect enhancer; (ii) toehold‐possessed DNA dressed on the...
A novel enzyme‐induced metallization colorimetric assay is developed to monitor and measure beta‐galactosidase (β‐gal) activity, and is further employed for colorimetric bacteriophage (phage)‐enabled detection of Escherichia coli (E. coli). This assay relies on enzymatic reaction‐induced silver deposition on the surface of gold nanorods (AuNRs). In the presence of β‐gal, the substrate p‐aminophenyl...
Surface modifications of plasmonic nanoparticles with metal adsorbates are essential in applications such as plasmonic sensing, plasmon‐enhanced photocatalysis, etc., where spectral broadening is usually observed. A single particle study is presented on plasmon damping by adsorption of platinum (Pt) clusters. Single particle dark‐field spectroscopy is employed to measure exactly the same gold nanorod...
Encapsulation of gold nanorods together with Nd‐doped fluorescent nanoparticles in a biocompatible polymer creates multifunctional nanostructures, whose infrared fluorescence allows their subcutaneous localization in biological tissues while also adding the ability to measure the temperature from the emitted light in order to better monitor the light‐to‐heat conversion of the gold nanorods during...
Binary 1D nanowires consisting of both SnO2 nanoparticles and Au nanorods are fabricated through a “substrate–particle solution template” assembling method, which shows highly enhanced gas sensitivity toward acetone under ambient conditions.
The synthesis and surface modification of gold nanorods (GNRs) is one of the most important and basic issues in nanoscience. Most of the widely investigated GNRs are coated with a cetyltrimethylammonium bromide(CTAB) bilayer. Here, a highly efficient method is proposed to replace CTAB from the surface of GNRs with a bifunctional 11‐mercaptoundecanoic acid in order to decrease the possible toxicity...
A one‐step soft lithography based pathway to manufacture aligned gold nanorod@poly‐(N‐isopropylacrylamide) (GNR@pNIPAM) hybrid chains with hexagonal arrangement of the nanorods and with an anisotropic optical response is presented. After demonstration of an efficient synthesis protocol, yielding uniform composite microgels in high concentration, a micromolding procedure using wrinkled polydimethylsiloxane...
Biorecognition is central to various biological processes and finds numerous applications in virtually all areas of chemistry, biology, and medicine. Artificial antibodies, produced by imprinting synthetic polymers, are designed to mimic the biological recognition capability of natural antibodies, while exhibiting superior thermal, chemical, and environmental stability compared to their natural counterparts...
Directed assemblies of anisotropic metal nanoparticles exhibit attractive physical and chemical properties. However, an effective methodology to prepare differently directed assemblies from the same anisotropic nanoparticles is not yet available. Gold nanorods (AuNRs) region‐selectively modified with different DNA strands can form side‐by‐side (SBS) and end‐to‐end (ETE) assemblies in a non‐crosslinking...
In article number 1702137, by Tohru Takarada and co‐workers, directed assembly of gold nanoroads, whose surface is densely modified with short DNA duplexes is achieved. Side‐by‐side and end‐to‐end assemblies are readily afforded due to the simultaneous stacking interaction between terminal base pairs of the DNA duplexes and repulsive steric forces induced by fraying motion of terminal‐mismatched nucleobases...
As a characteristic trait of most tumor types, metastasis is the major cause of the death of patients. In this study, a photothermal agent based on gold nanorod is coated with metal (Gd3+)‐organic (polyphenol) network to realize combination therapy for metastatic tumors. This nanotheranostic system significantly enhances antitumor therapeutic effects in vitro and in vivo with the combination of photothermal...
In article number 1704230, Hideyuki Mitomo, Kuniharu Ijiro, and co‐workers introduce a thermoresponsive two‐step assembly of rod‐shaped gold nanoparticles (GNRs) by a simple surface modification with a single kind of ligand. As dehydration temperature of the surface ligand varies depending on the degree of curvature, GNRs form side‐by‐side assemblies first, and then form assembled‐assemblies on heating,...
Gold nanorods (GNRs) coated with a single kind of ligand show thermoreponsive two‐step assembly to provide a hierarchical structure. The GNRs (33 nm in length × 14 nm in diameter) coated with a hexa(ethylene glycol) (HEG) derivative form side‐by‐side assemblies at 30 °C (TA1) as a steady state through dehydration. By further heating to over 40 °C (TA2), larger assemblies, which are composed of the...
Seed‐mediated methods employing cetyltrimethylammonium bromide (CTAB) as a surfactant, and silver salts as additives, are the most common synthetic strategies for high‐yield productions of quality Au nanorods. However, the mechanism of these reactions is not yet fully understood and, importantly, significant lab‐to‐lab reproducibility issues still affect these protocols. In this study, the direct...
Gold nanorods (AuNRs), with their unique physicochemical properties, are recognized as promising materials for biomedical applications. Chemical modification of their surfaces is attracting increasing attention with regard to cytotoxicity and cellular uptake. Herein, the toxicological effects of three types of polymer‐coated AuNRs, which are cetyltrimethylammonium bromide‐coated AuNRs, polystyrene...
A new class of solvent free, lyotropic liquid crystal nanocomposites based on gold nanorods (AuNRs) with high nanorod content is reported. Application of shear results in switchable, highly ordered alignment of the nanorods over several centimeters with excellent storage stability for months. For the synthesis, AuNRs are surface functionalized with a charged, covalently tethered corona, which induces...
Gold nanorods (Au NRs) have attracted great attention owing to their significant role in catalysis, imaging, and photothermal therapy. The internal atomic structure control of metallic NRs has long been a challenge. In article number 2001101, Jianfeng Yan and co‐workers demonstrate the concept of internal atomic structures tailored with light, and Au NRs with various internal atomic structure are...
Laser processing of gold nanorods (Au NRs) relying on light–matter interaction provides great opportunities in various potential applications. Unveiling the light‐induced structure change is a crucial goal in order to control the shape and related properties for practical application. However, the internal atomic structure control of metallic NRs has long been a challenge. Here, the concept of internal...
Photothermal therapy (PTT) has attracted tremendous attention due to its noninvasiveness and localized treatment advantages. However, heat shock proteins (HSPs) associated self‐preservation mechanisms bestow cancer cells thermoresistance to protect them from the damage of PTT. To minimize the thermoresistance of cancer cells and improve the efficacy of PTT, an integrated on‐demand nanoplatform composed...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.