The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Summary. The design of experiments for generalized non‐linear models is investigated and applied to an optical process for characterizing interfaces which is widely used in the physical and natural sciences. Design strategies for overcoming the dependence of a D‐optimal design on the values of the model parameters are explored, including the use of Bayesian designs. Designs for the accurate estimation...
Summary. Data from experiments in steady state enzyme kinetic studies and radioligand binding assays are usually analysed by fitting non‐linear models developed from biochemical theory. Designing experiments for fitting non‐linear models is complicated by the fact that the variances of parameter estimates depend on the unknown values of these parameters and Bayesian optimal exact design for non‐linear...
Summary. One attractive feature of optimum design criteria, such as D‐ and A‐optimality, is that they are directly related to statistically interpretable properties of the designs that are obtained, such as minimizing the volume of a joint confidence region for the parameters. However, the assumed relationships with inferential procedures are valid only if the variance of experimental units is assumed...
Many chemical and biological experiments involve multiple treatment factors and often it is convenient to fit a non‐linear model in these factors. This non‐linear model can be mechanistic, empirical or a hybrid of the two. Motivated by experiments in chemical engineering, we focus on D‐optimal designs for multifactor non‐linear response surfaces in general. To find and study optimal designs, we first...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.