Ewing tumors are the most frequent malignant tumors of the chest wall in children and young adults. Surgical management of these tumors can be challenging. Optimal local control remains controversial. The aim of this study was to analyze treatment, outcome, and surgical procedures in patients with thoracic tumors of the Ewing sarcoma family (TES) treated within four Cooperative Soft‐Tissue...
The availability of robust, equivalent data regarding outcomes for upfront or delayed surgery for renal tumors in children leads to a dilemma in selecting the initial treatment. Imaging criteria associated with the probability of rupture or incomplete resection may provide a more objective assessment for customization for the timing of surgery.
Eighty‐three children with unilateral,...
We present the preliminary results of robotic‐assisted laparoscopic (RAL) total and partial nephrectomy for renal malignant tumors in children.
This is a prospective study of patients operated with RAL between December 2016 and September 2018. Patients with Wilms tumors were treated according to the SIOP‐2001 protocol. Patient and tumor characteristics, type of surgery, surgical‐related...
Prognosis of dumbbell neuroblastoma (NBL) is mainly determined by the sequelae induced by the tumor itself and the neurosurgical approach. However, after primary chemotherapy, surgical management of the residual tumor, especially the spinal canal component, remains controversial.
We conducted a single‐center retrospective cohort study over the last 15 years (2002–2017) including...
Wilms tumor (WT) is the most common renal tumor in children. We describe the outcomes for patients with WT that metastasized to bone (WTBM) to assist in decision making for these uncommon patients.
We retrospectively reviewed the research records of patients identified with WTBM from the National Wilms Tumor Study (NWTS 1–5) database. We then related overall survival (OS) to...
Sickle cell disease (SCD) is the most common genetic disease in France. In developing countries, it is associated with a high incidence of hearing loss. The aim of this study was to determine the prevalence of hearing loss in French children with SCD in order to determine if they need a close audiological follow‐up.
We performed a single‐center prospective cross‐sectional study...
Providing evidence‐based supportive care for children with cancer has the potential to optimize treatment outcomes and improve quality of life. The Children's Oncology Group (COG) Supportive Care Guidelines Subcommittee conducted a systematic review to identify current supportive care clinical practice guidelines (CPGs) relevant to childhood cancer or pediatric hematopoietic stem cell transplant....
This study evaluates the outcome of Wilms tumor (WT) following introduction of multidisciplinary team management and patient treatment stratification by tumor histology in two referral centers in southeastern Nigeria.
We analyzed histologically confirmed WT cases managed from January 2008 to June 2017.
There were 45 patients, peak age incidence of 2 to 5 years...
Improvements during 1978 to 2006 in the 5‐year survival rate of adolescents and young adults (AYAs, age 15–39) and children with cancers common to both age groups were evaluated for 1978 to 2006 in Europe and the USA. AYAs had absolute survival increases of 25% and 15% in Europe and the USA, respectively, but in both cases, AYA 5‐year survival was, as of 2006, 4% lower than those in children. Acute...
Adaptive behavior, i.e., the performance on daily activities required for personal and social independence, is essential to estimate in children with low‐grade glioma (LGG) since most of them are long‐term survivors. Our aim was to investigate adaptive behavior in children with LGG.
In a cross‐sectional study, adaptive behavior was assessed using the paper pencil version of the...
Outcome for patients with metastatic or recurrent/refractory osteosarcoma remains poor. Responses to sorafenib, a multikinase inhibitor, have been seen in recurrent/refractory osteosarcoma, although specific biomarkers of response have not been described. We report a partial response in a 7‐year‐old with refractory osteosarcoma treated with sorafenib 200 mg twice daily. Toxicities included Common...
Financed by the National Centre for Research and Development under grant No. SP/I/1/77065/10 by the strategic scientific research and experimental development program:
SYNAT - “Interdisciplinary System for Interactive Scientific and Scientific-Technical Information”.